The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

metaxalone
Synonyms

C12H15NO3

5-(3,5-dimethylphenoxymethyl)-1,3-oxazolidin-2-one
ID

http://purl.obolibrary.org/obo/dinto_DB00660
CASRN

1665-48-1
DBBrand

zorane

skelaxin
DBSynonym

metazolone

metaxalon

metaxalonum [inn-latin]

metaxalonum [latin]

metaxalona [inn-spanish]

metassalone [dcit]

methaxalonum

metazalone

methoxolone
Definition

Metaxalone (marketed by King Pharmaceuticals under the brand name Skelaxin?) is a muscle relaxant used to relax muscles and relieve pain caused by strains, sprains, and other musculoskeletal conditions. Its exact mechanism of action is not known, but it may be due to general central nervous system depression. It is considered to be a moderately strong muscle relaxant, with relatively low incidence of side effects. Skelaxin comes in an 800 mg scored tablet. It previously came in both 400 mg and 800 mg tablets. The 400 mg tablet has been discontinued. Possible side effects include nausea, vomiting, drowsiness and CNS side effects such as dizziness, headache, and irritability.
InChI

InChI=1S/C12H15NO3/c1-8-3-9(2)5-10(4-8)15-7-11-6-13-12(14)16-11/h3-5,11H,6-7H2,1-2H3,(H,13,14)
InChIKey

InChIKey=IMWZZHHPURKASS-UHFFFAOYSA-N
label

metaxalone
may interact with

http://purl.obolibrary.org/obo/dinto_DB00427
prefixIRI

obo2:dinto_DB00660
prefLabel

metaxalone
SMILES

CC1=CC(OCC2CNC(=O)O2)=CC(C)=C1
Synonym

C12H15NO3

5-(3,5-dimethylphenoxymethyl)-1,3-oxazolidin-2-one
xref

PubChem Compound:15459

ChemSpider:14709

PharmGKB:PA164747189

PubChem Substance:46506253

Drugs.com:http://www.drugs.com/cdi/metaxalone.html

Wikipedia:http://en.wikipedia.org/wiki/Metaxalone

RxList:http://www.rxlist.com/cgi/generic/metax.htm

National Drug Code Directory:0185-0448-01
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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