The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

mecamylamine
Synonyms

C11H21N

N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine

ID

http://purl.obolibrary.org/obo/dinto_DB00657

ATCCode

C02BB01

binds

http://purl.obolibrary.org/obo/dinto_2747

CASRN

60-40-2

DBBrand

mecamine

versamine

inversine

mevasin hydrochloride

mekamin hydrochloride

mevasine

inversine hydrochloride

revertina

mecamine hydrochloride

mekamine

DBSynonym

3-methylaminoisocamphane hydrochloride

2-methylamino-2,3,3-trimethylnorbornane

3-methylaminoisocamphane

mecamilamina

2-methylaminoisocamphane

mecamylamine hydrochloride

Definition

A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool. [PubChem]

has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000589

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0001068

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000306

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0001345

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2747

InChI

InChI=1S/C11H21N/c1-10(2)8-5-6-9(7-8)11(10,3)12-4/h8-9,12H,5-7H2,1-4H3

InChIKey

InChIKey=IMYZQPCYWPFTAG-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2747

label

mecamylamine

prefixIRI

obo2:dinto_DB00657

prefLabel

mecamylamine

SMILES

CNC1(C)C2CCC(C2)C1(C)C

Synonym

C11H21N

N,2,3,3-tetramethylbicyclo[2.2.1]heptan-2-amine

xref

ChemSpider:3892

RxList:http://www.rxlist.com/cgi/generic2/mecamylamine.htm

BindingDB:50061565

Guide To Pharmacology:3990

National Drug Code Directory:17205-0626-1

Wikipedia:http://en.wikipedia.org/wiki/Mecamylamine

PubChem Compound:4032

PubChem Substance:46508607

PharmGKB:PA450334

IUPHAR:3990

Drugs.com:http://www.drugs.com/cdi/mecamylamine.html

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_6706 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6706 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6706 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6706 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_6706 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6706 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6706 DDSS LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Mecamylamine APAONTO LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66063 NCIT LOOM
http://id.nlm.nih.gov/mesh/D008464 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008464 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00657 MDM LOOM
http://purl.jp/bio/4/id/200906067218506333 IOBC LOOM
http://purl.bioontology.org/ontology/RXNORM/6673 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.849.575.781.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/NCIT_C66063 BERO LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147896 NDFRT LOOM
http://purl.obolibrary.org/obo/XCO_0000843 XCO LOOM
http://purl.obolibrary.org/obo/OMIT_0009530 OMIT LOOM
http://purl.bioontology.org/ontology/VANDF/4019807 VANDF LOOM
http://stirdf.jst.go.jp/id/200907016841388724 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372828008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/CSP/2088-1493 CRISP LOOM
http://purl.obolibrary.org/obo/MESH_D008464 BERO LOOM
http://purl.bioontology.org/ontology/SNMI/C-811A0 SNMI LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017098 PMAPP-PMO LOOM
http://www.drugbank.ca/drugs/DB00657 FTC LOOM
http://purl.bioontology.org/ontology/ATC/C02BB01 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D008464 MESH LOOM