loading...| Preferred Name | mitotane | |
| Synonyms |
1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene C14H10Cl4 |
|
| ID |
http://purl.obolibrary.org/obo/dinto_DB00648 |
|
| AHFScode |
10:00.00 |
|
| ATCCode |
L01XX23 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_2146 http://purl.obolibrary.org/obo/dinto_3535 |
|
| CASRN |
53-19-0 |
|
| DBBrand |
mitotanum [inn-latin] chlodithan lysodren chlodithane mitotan chloditan khlodithan |
|
| Definition |
A derivative of the insecticide dichlorodiphenyldichloroethane that specifically inhibits cells of the adrenal cortex and their production of hormones. It is used to treat adrenocortical tumors and causes CNS damage, but no bone marrow depression. [PubChem] |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000642 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000460 |
|
| has pharmacological target | ||
| InChI |
InChI=1S/C14H10Cl4/c15-10-7-5-9(6-8-10)13(14(17)18)11-3-1-2-4-12(11)16/h1-8,13-14H |
|
| InChIKey |
InChIKey=JWBOIMRXGHLCPP-UHFFFAOYSA-N |
|
| induces | ||
| label |
mitotane |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_9241 |
|
| prefixIRI |
obo2:dinto_DB00648 |
|
| prefLabel |
mitotane |
|
| related with |
http://purl.obolibrary.org/obo/dinto_2146 |
|
| SMILES |
ClC(Cl)C(C1=CC=C(Cl)C=C1)C1=CC=CC=C1Cl |
|
| Synonym |
1-chloro-4-[2,2-dichloro-1-(2-chlorophenyl)ethyl]benzene C14H10Cl4 |
|
| xref |
PubChem Substance:46508319 National Drug Code Directory:0015-3080-60 ChemSpider:4066 Drugs.com:http://www.drugs.com/cdi/mitotane.html Wikipedia:http://en.wikipedia.org/wiki/Mitotane Drugs Product Database (DPD):463221 RxList:http://www.rxlist.com/cgi/generic2/mitotane.htm PubChem Compound:4211 PharmGKB:PA164746157 |
|
| subClassOf |