The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

piperazine
Synonyms

C4H10N2

piperazine

ID

http://purl.obolibrary.org/obo/dinto_DB00592

activates

http://purl.obolibrary.org/obo/dinto_1457

AHFScode

92:02.00*

08:08.00

ATCCode

R03DA09

P02CB01

binds

http://purl.obolibrary.org/obo/dinto_1457

http://purl.obolibrary.org/obo/dinto_2993

CASRN

110-85-0

DBBrand

pipersol

multifuge

asca-trol no. 3

tensofin

tasnon

lumbrical

vermizine

moditen

antepar

pacinol

dispermine

permitil

omca

upixon

worm-away

worm-a-ton

dapotum

uvilon

anatensol

wurmirazin

vermidol

vermex

piperazidine

eraverm

antiren

DBSynonym

piperazin

piperazin [germany]

diethyleneimine

piperazine hexahydrate

hexahydropyrazine

diethylenediamine

piperazine hydrate

fluphenazine dihydrochloride

Definition

Piperazine is an organic compound that consists of a six-membered ring containing two opposing nitrogen atoms. Piperazine exists as small alkaline deliquescent crystals with a saline taste. Piperazine was introduced to medicine as a solvent for uric acid. When taken into the body the drug is partly oxidized and partly eliminated unchanged. Outside the body, piperazine has a remarkable power to dissolve uric acid and producing a soluble urate, but in clinical experience it has not proved equally successful. Piperazine was first introduced as an anthelmintic in 1953. A large number of piperazine compounds have anthelmintic action. Their mode of action is generally by paralysing parasites, which allows the host body to easily remove or expel the invading organism.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1457

InChI

InChI=1S/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H2

InChIKey

InChIKey=GLUUGHFHXGJENI-UHFFFAOYSA-N

is metabolised by

http://purl.obolibrary.org/obo/dinto_2993

is substrate of

http://purl.obolibrary.org/obo/dinto_2993

label

piperazine

modulates

http://purl.obolibrary.org/obo/dinto_1457

prefixIRI

obo2:dinto_DB00592

prefLabel

piperazine

SMILES

C1CNCCN1

Synonym

C4H10N2

piperazine

xref

Wikipedia:http://en.wikipedia.org/wiki/Piperazine

PubChem Substance:46507642

PubChem Compound:4837

PharmGKB:PA450977

Drugs Product Database (DPD):97128

ChEBI:28568

PDB:169

ChemSpider:13835459

Drugs.com:http://www.drugs.com/cons/piperazine.html

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Delete Mapping To Ontology Source
http://sbmi.uth.tmc.edu/ontology/ochv#C0031957 OCHV LOOM
http://www.drugbank.ca/drugs/DB00592 FTC LOOM
http://purl.jp/bio/4/id/200906098212553740 IOBC LOOM
http://purl.obolibrary.org/obo/NCIT_C61892 BERO LOOM
https://go.drugbank.com/drugs/DB00592 MDM LOOM
http://purl.bioontology.org/ontology/RCD/eq2.. RCD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/428714003 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61892 NCIT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9746 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147982 NDFRT LOOM
http://purl.bioontology.org/ontology/CSP/2332-0723 CRISP LOOM
http://www.co-ode.org/ontologies/galen#Piperazine GALEN LOOM
http://purl.obolibrary.org/obo/CHEBI_26144 GSSO LOOM
http://purl.bioontology.org/ontology/VANDF/4019897 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D000077489 MESH LOOM
http://purl.bioontology.org/ontology/ATC/P02CB01 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/8340 RXNORM LOOM
http://stirdf.jst.go.jp/id/200907089013174548 IOBC LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_28568 DRON LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026666 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C034930 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDDF/002977 NDDF LOOM