The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	mazindol
Synonyms	5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol C16H13ClN2O
ID	http://purl.obolibrary.org/obo/dinto_DB00579
ATCCode	A08AA05
binds	http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_3343 http://purl.obolibrary.org/obo/dinto_0068
CASRN	22232-71-9
DBBrand	dea no. 1605 mazanor mazindol [usan:ban:inn] mazildene terenac sanorex dimagrir mazindolum [inn-latin] magrilon teronac
Definition	Tricyclic anorexigenic agent unrelated to and less toxic than amphetamine, but with some similar side effects. It inhibits uptake of catecholamines and blocks the binding of cocaine to the dopamine uptake transporter. [PubChem]
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_3343 http://purl.obolibrary.org/obo/dinto_0068
InChI	InChI=1S/C16H13ClN2O/c17-12-7-5-11(6-8-12)16(20)14-4-2-1-3-13(14)15-18-9-10-19(15)16/h1-8,20H,9-10H2
InChIKey	InChIKey=ZPXSCAKFGYXMGA-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_2714 http://purl.obolibrary.org/obo/dinto_3343 http://purl.obolibrary.org/obo/dinto_0068
label	mazindol
may interact with	http://purl.obolibrary.org/obo/CHEBI_9943 http://purl.obolibrary.org/obo/CHEBI_31981 http://purl.obolibrary.org/obo/dinto_DB00902 http://purl.obolibrary.org/obo/CHEBI_6838 http://purl.obolibrary.org/obo/CHEBI_8028 http://purl.obolibrary.org/obo/CHEBI_7936 http://purl.obolibrary.org/obo/CHEBI_3647 http://purl.obolibrary.org/obo/CHEBI_8491 http://purl.obolibrary.org/obo/CHEBI_9711 http://purl.obolibrary.org/obo/dinto_DB01246 http://purl.obolibrary.org/obo/CHEBI_45951 http://purl.obolibrary.org/obo/CHEBI_6780 http://purl.obolibrary.org/obo/CHEBI_9566 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_8459 http://purl.obolibrary.org/obo/CHEBI_5123 http://purl.obolibrary.org/obo/CHEBI_2401 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/CHEBI_8461 http://purl.obolibrary.org/obo/CHEBI_8435 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/dinto_DB00752 http://purl.obolibrary.org/obo/CHEBI_5557 http://purl.obolibrary.org/obo/CHEBI_63620 http://purl.obolibrary.org/obo/CHEBI_313639 http://purl.obolibrary.org/obo/CHEBI_9544 http://purl.obolibrary.org/obo/CHEBI_5118
prefixIRI	obo2:dinto_DB00579
prefLabel	mazindol
SMILES	OC1(N2CCN=C2C2=CC=CC=C12)C1=CC=C(Cl)C=C1
Synonym	5-(4-chlorophenyl)-2H,3H,5H-imidazo[2,1-a]isoindol-5-ol C16H13ClN2O
xref	Wikipedia:http://en.wikipedia.org/wiki/Mazindol PharmGKB:PA450326 PubChem Substance:46509094 Drugs Product Database (DPD):432407 BindingDB:50005536 ChemSpider:3880 Drugs.com:http://www.drugs.com/mtm/mazindol.html PubChem Compound:4020
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008454	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_6702	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_6702	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6702	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_6702	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_6702	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_6702	DRON	LOOM
http://purl.bioontology.org/ontology/CSP/4001-0076	CRISP	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387232005	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/LNC/LP18071-8	LOINC	LOOM
http://www.co-ode.org/ontologies/galen#Mazindol	GALEN	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU003335	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.513.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/MESH/D008454	MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/6664	RXNORM	LOOM
http://purl.bioontology.org/ontology/RCD/df3..	RCD	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146368	NDFRT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#7818	OCHV	LOOM
http://stirdf.jst.go.jp/id/200907080855172821	IOBC	LOOM
https://go.drugbank.com/drugs/DB00579	MDM	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017942	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0024977	OCHV	LOOM
http://purl.bioontology.org/ontology/VANDF/4018025	VANDF	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Mazindol	STMSO	LOOM
http://purl.bioontology.org/ontology/NDDF/001874	NDDF	LOOM
http://www.drugbank.ca/drugs/DB00579	FTC	LOOM
http://purl.obolibrary.org/obo/NCIT_C66057	BERO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66057	NCIT	LOOM
http://purl.obolibrary.org/obo/OMIT_0009520	OMIT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-65510	SNMI	LOOM
http://purl.obolibrary.org/obo/MESH_D008454	BERO	LOOM
http://purl.jp/bio/4/id/200906061657867816	IOBC	LOOM
http://purl.bioontology.org/ontology/ATC/A08AA05	ATC	LOOM