The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

nelfinavir
Synonyms

C32H45N3O4S

(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide
ID

http://purl.obolibrary.org/obo/dinto_DB00220
AHFScode

08:18.08.08
ATCCode

J05AE04
binds

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_3326

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_0465
CASRN

159989-64-7
DBBrand

viracept
DBSynonym

nelfinavir mesylate

nlf

nfv

ag1343

1un
Definition

A potent HIV-1 protease inhibitor. It is used in combination with other antiviral drugs in the treatment of HIV in both adults and children. [PubChem]
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000479

http://purl.obolibrary.org/obo/OAE_0000492

http://purl.obolibrary.org/obo/OAE_0000596

http://purl.obolibrary.org/obo/OAE_0000443

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000195

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000210

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0001053

http://purl.obolibrary.org/obo/OAE_0000770

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001057

http://purl.obolibrary.org/obo/OAE_0001190

http://purl.obolibrary.org/obo/OAE_0000086

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000525

http://purl.obolibrary.org/obo/OAE_0000495

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000401

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0001403

http://purl.obolibrary.org/obo/OAE_0000405

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000468

http://purl.obolibrary.org/obo/OAE_0001217

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000211

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target

http://purl.obolibrary.org/obo/dinto_3326
InChI

InChI=1S/C32H45N3O4S/c1-21-25(15-10-16-28(21)36)30(38)33-26(20-40-24-13-6-5-7-14-24)29(37)19-35-18-23-12-9-8-11-22(23)17-27(35)31(39)34-32(2,3)4/h5-7,10,13-16,22-23,26-27,29,36-37H,8-9,11-12,17-20H2,1-4H3,(H,33,38)(H,34,39)/t22-,23+,26-,27-,29+/m0/s1
InChIKey

InChIKey=QAGYKUNXZHXKMR-HKWSIXNMSA-N
induces

http://purl.obolibrary.org/obo/dinto_1440
inhibits

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_1970

http://purl.obolibrary.org/obo/dinto_0883

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_3326

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_0465
is metabolised by

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1956
is substrate of

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1956

http://purl.obolibrary.org/obo/dinto_1440
is transported by

http://purl.obolibrary.org/obo/dinto_1440
label

nelfinavir
may interact with

http://purl.obolibrary.org/obo/dinto_DB00906

http://purl.obolibrary.org/obo/dinto_DB00683

http://purl.obolibrary.org/obo/CHEBI_8212

http://purl.obolibrary.org/obo/CHEBI_32250

http://purl.obolibrary.org/obo/CHEBI_391960

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/dinto_DB00801

http://purl.obolibrary.org/obo/CHEBI_585948

http://purl.obolibrary.org/obo/CHEBI_4317

http://purl.obolibrary.org/obo/CHEBI_71940

http://purl.obolibrary.org/obo/CHEBI_68642

http://purl.obolibrary.org/obo/CHEBI_41774

http://purl.obolibrary.org/obo/dinto_DB00541

http://purl.obolibrary.org/obo/dinto_DB00243

http://purl.obolibrary.org/obo/CHEBI_499361

http://purl.obolibrary.org/obo/CHEBI_10127

http://purl.obolibrary.org/obo/dinto_DB01591

http://purl.obolibrary.org/obo/CHEBI_31547

http://purl.obolibrary.org/obo/CHEBI_4858

http://purl.obolibrary.org/obo/CHEBI_4031

http://purl.obolibrary.org/obo/CHEBI_61049

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_9150

http://purl.obolibrary.org/obo/CHEBI_3756

http://purl.obolibrary.org/obo/dinto_DB06287

http://purl.obolibrary.org/obo/dinto_DB00342

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_63632

http://purl.obolibrary.org/obo/CHEBI_3611

http://purl.obolibrary.org/obo/CHEBI_68595

http://purl.obolibrary.org/obo/CHEBI_40303

http://purl.obolibrary.org/obo/dinto_DB01410

http://purl.obolibrary.org/obo/CHEBI_133809

http://purl.obolibrary.org/obo/dinto_DB01323

http://purl.obolibrary.org/obo/dinto_DB00570

http://purl.obolibrary.org/obo/dinto_DB01357

http://purl.obolibrary.org/obo/CHEBI_3761

http://purl.obolibrary.org/obo/CHEBI_10125

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/dinto_DB01558

http://purl.obolibrary.org/obo/CHEBI_2611

http://purl.obolibrary.org/obo/CHEBI_75988

http://purl.obolibrary.org/obo/CHEBI_63637

http://purl.obolibrary.org/obo/dinto_DB08901

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/dinto_DB01588

http://purl.obolibrary.org/obo/CHEBI_39548

http://purl.obolibrary.org/obo/CHEBI_480999

http://purl.obolibrary.org/obo/CHEBI_9622

http://purl.obolibrary.org/obo/CHEBI_6807

http://purl.obolibrary.org/obo/CHEBI_9398

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_32315

http://purl.obolibrary.org/obo/CHEBI_421707

http://purl.obolibrary.org/obo/CHEBI_28593

http://purl.obolibrary.org/obo/dinto_DB01118

http://purl.obolibrary.org/obo/CHEBI_9139

http://purl.obolibrary.org/obo/dinto_DB00977

http://purl.obolibrary.org/obo/CHEBI_4513

http://purl.obolibrary.org/obo/CHEBI_49575

http://purl.obolibrary.org/obo/dinto_DB00690

http://purl.obolibrary.org/obo/CHEBI_63584

http://purl.obolibrary.org/obo/CHEBI_2896

http://purl.obolibrary.org/obo/CHEBI_119915

http://purl.obolibrary.org/obo/CHEBI_50922

http://purl.obolibrary.org/obo/CHEBI_114785

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB02703

http://purl.obolibrary.org/obo/dinto_DB01589

http://purl.obolibrary.org/obo/dinto_DB01346

http://purl.obolibrary.org/obo/CHEBI_63613

http://purl.obolibrary.org/obo/CHEBI_9674

http://purl.obolibrary.org/obo/CHEBI_71272

http://purl.obolibrary.org/obo/CHEBI_38940

http://purl.obolibrary.org/obo/dinto_DB01341

http://purl.obolibrary.org/obo/CHEBI_64318

http://purl.obolibrary.org/obo/CHEBI_46295

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/CHEBI_4562
prefixIRI

obo2:dinto_DB00220
prefLabel

nelfinavir
SMILES

[H][C@@]12CCCC[C@]1([H])CN(C[C@@H](O)[C@H](CSC1=CC=CC=C1)NC(=O)C1=C(C)C(O)=CC=C1)[C@@H](C2)C(=O)NC(C)(C)C
Synonym

C32H45N3O4S

(3S,4aS,8aS)-N-tert-butyl-2-[(2R,3R)-2-hydroxy-3-[(3-hydroxy-2-methylphenyl)formamido]-4-(phenylsulfanyl)butyl]-decahydroisoquinoline-3-carboxamide
xref

RxList:http://www.rxlist.com/cgi/generic2/nelfin.htm

National Drug Code Directory:63010-010-30

ChemSpider:57718

Drugs.com:http://www.drugs.com/cdi/nelfinavir.html

BindingDB:518

PubChem Substance:46507719

Drugs Product Database (DPD):2248761

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/vir1483.shtml

PubChem Compound:64143

Wikipedia:http://en.wikipedia.org/wiki/Nelfinavir

PharmGKB:PA450606
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Delete Mapping To Ontology Source
http://purl.bioontology.org/ontology/NDDF/006408 NDDF LOOM
http://purl.obolibrary.org/obo/DRON_00013466 INBANCIDO LOOM
http://purl.obolibrary.org/obo/DRON_00013466 CIDO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.531.520 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/134527 RXNORM LOOM
http://purl.obolibrary.org/obo/OMIT_0019859 OMIT LOOM
http://purl.bioontology.org/ontology/CSP/5000-0054 CRISP LOOM
http://stirdf.jst.go.jp/id/200907015344690488 IOBC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373445001 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Nelfinavir GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#38385 OCHV LOOM
http://purl.obolibrary.org/obo/NCIT_C29285 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 INBANCIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 HOIP LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 TXPO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 CIDO LOOM
http://purl.obolibrary.org/obo/CHEBI_7496 CHEBI LOOM
https://go.drugbank.com/drugs/DB00220 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D019888 RH-MESH LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017750 PMAPP-PMO LOOM
http://purl.jp/bio/4/id/200906027838035622 IOBC LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000022055 INBANCIDO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000022055 CIDO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0525005 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/MTHU013848 LOINC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022055 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/J05AE04 ATC LOOM
http://purl.bioontology.org/ontology/LNC/LP21313-9 LOINC LOOM
http://www.semanticweb.org/zchero/ontologies/2023/11/SepsisOntology#Nelfinavir SEPON LOOM
http://scai.fraunhofer.de/HuPSON#SCAIVPH_00001130 HUPSON LOOM
http://purl.bioontology.org/ontology/RCD/eiL.. RCD LOOM
http://purl.bioontology.org/ontology/VANDF/4024050 VANDF LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29285 NCIT LOOM
http://purl.obolibrary.org/obo/MESH_D019888 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D019888 MESH LOOM