The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

insulin lispro
Synonyms
ID

http://purl.obolibrary.org/obo/dinto_DB00046

activates

http://purl.obolibrary.org/obo/dinto_0892

AHFScode

68:20.08

ATCCode

A10AC04

A10AB04

A10AD04

binds

http://purl.obolibrary.org/obo/dinto_2264

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_0892

CASRN

133107-64-9

DBBrand

humalog pen

humalog kwikpen

humalog

DBSynonym

insulin lispro recombinant

Definition

Insulin lispro is a recombinant human insulin analogue produced in a specialized laboratory strain of Escherischia coli. Plasmid DNA transfected into the bacteria encodes for an analogue of human insulin that has a lysine at residuce B28 and proline at B29; these residues are reversed in endogenous human insulin. Reversal of these amino acid residues produces a rapid-acting insulin analogue. FDA approved on 1996.

has effect

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000418

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0001057

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350

has pharmacological target

http://purl.obolibrary.org/obo/dinto_0892

induces

http://purl.obolibrary.org/obo/dinto_2651

label

insulin lispro

may interact with

http://purl.obolibrary.org/obo/CHEBI_5001

http://purl.obolibrary.org/obo/CHEBI_28918

http://purl.obolibrary.org/obo/CHEBI_8497

http://purl.obolibrary.org/obo/CHEBI_6541

http://purl.obolibrary.org/obo/dinto_DB00806

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/dinto_DB01278

http://purl.obolibrary.org/obo/dinto_DB00104

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/CHEBI_8774

http://purl.obolibrary.org/obo/CHEBI_8382

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/dinto_DB00999

http://purl.obolibrary.org/obo/CHEBI_4657

http://purl.obolibrary.org/obo/CHEBI_4784

http://purl.obolibrary.org/obo/CHEBI_5118

modulates

http://purl.obolibrary.org/obo/dinto_0892

prefixIRI

obo2:dinto_DB00046

prefLabel

insulin lispro

related with

http://purl.obolibrary.org/obo/dinto_2264

xref

Drugs.com:http://www.drugs.com/mtm/insulin-lispro.html

RxList:http://www.rxlist.com/cgi/generic/insulinlispro.htm

PharmGKB:PA164747059

National Drug Code Directory:0002-7510-01

Drugs Product Database (DPD):2241283

Wikipedia:http://en.wikipedia.org/wiki/Insulin_lispro

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_232799 CHEBI LOOM
http://purl.obolibrary.org/obo/DRON_00017625 DRON LOOM
http://purl.bioontology.org/ontology/NDDF/006061 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C29123 BERO LOOM
http://purl.obolibrary.org/obo/DRON_00017625 PDRO LOOM
http://purl.obolibrary.org/obo/DRON_00017625 DDSS LOOM
https://go.drugbank.com/drugs/DB00046 MDM LOOM
http://purl.obolibrary.org/obo/MESH_D061268 BERO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D06.472.699.587.200.400.500 RH-MESH LOOM
http://www.semanticweb.org/khaled/ontologies/2024/7/CDMOnto#Insulin-Lispro CDMONTO LOOM
http://purl.bioontology.org/ontology/ATC/A10AD04 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D061268 RH-MESH LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000752177 PDQ LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/412210000 SNOMEDCT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D12.644.548.586.200.400.500 RH-MESH LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C29123 NCIT LOOM
http://purl.bioontology.org/ontology/ATC/A10AB04 ATC LOOM
http://purl.bioontology.org/ontology/RXNORM/86009 RXNORM LOOM
http://purl.jp/bio/4/id/200906051482068464 IOBC LOOM
http://www.drugbank.ca/drugs/DB00046 FTC LOOM
http://purl.bioontology.org/ontology/RCD/f13.. RCD LOOM
http://www.co-ode.org/ontologies/galen#InsulinLispro GALEN LOOM
http://purl.bioontology.org/ontology/ATC/A10AC04 ATC LOOM
http://purl.bioontology.org/ontology/MESH/D061268 MESH LOOM
http://purl.obolibrary.org/obo/OMIT_0027940 OMIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00019147 PMAPP-PMO LOOM