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The Drug-Drug Interactions Ontology
Preferred Name | etanercept | |
Synonyms |
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ID |
http://purl.obolibrary.org/obo/dinto_DB00005 |
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AHFScode |
92:00.00
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ATCCode |
L04AB01
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binds |
http://purl.obolibrary.org/obo/dinto_2116 http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3181 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_3490 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_0795 http://purl.obolibrary.org/obo/dinto_3709 |
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CASRN |
185243-69-0
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DBBrand |
enbrel sureclick enbrel enbrel (immunex corp)
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DBSynonym |
tumor necrosis factor receptor 2 p75 cd120b tumor necrosis factor receptor type ii p80 tnf-alpha receptor tnf-r2 tumor necrosis factor receptor superfamily member 1b precursor
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Definition |
Dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. The Fc component of etanercept contains the CH2 domain, the CH3 domain and hinge region, but not the CH1 domain of IgG1. Etanercept is produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian cell expression system. It consists of 934 amino acids
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has pharmacological target | ||
inhibits | ||
label |
etanercept
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may interact with | ||
prefixIRI |
obo2:dinto_DB00005
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prefLabel |
etanercept
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related with |
http://purl.obolibrary.org/obo/dinto_3109 http://purl.obolibrary.org/obo/dinto_3105 http://purl.obolibrary.org/obo/dinto_3106 http://purl.obolibrary.org/obo/dinto_3107 http://purl.obolibrary.org/obo/dinto_3181 http://purl.obolibrary.org/obo/dinto_3078 http://purl.obolibrary.org/obo/dinto_3490 http://purl.obolibrary.org/obo/dinto_3084 http://purl.obolibrary.org/obo/dinto_3112 http://purl.obolibrary.org/obo/dinto_3111 http://purl.obolibrary.org/obo/dinto_0795 http://purl.obolibrary.org/obo/dinto_3709 |
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xref |
RxList:http://www.rxlist.com/cgi/generic/etanercept.htm Drugs.com:http://www.drugs.com/cdi/etanercept.html Drugs Product Database (DPD):2242903 National Drug Code Directory:58406-455-04 PharmGKB:PA449515 GenBank:M32315 UniProtKB:P20333 Wikipedia:http://en.wikipedia.org/wiki/Etanercept
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subClassOf |
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