The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

tubocurarine
Synonyms

d-tubocurarine

C37H41N2O6

7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium

7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium

Tubocurarin

Tubocurarine

(1S,16R)-9,21-dihydroxy-10,25-dimethoxy-15,15,30-trimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6}.1^{8,12}.1^{18,22}.0^{27,31}.0^{16,34}]hexatriaconta-3,5,8,10,12(34),18(33),19,21,24(32),25,27(31),35-dodecaen-15-ium

(+)-tubocurarine

ID

http://purl.obolibrary.org/obo/CHEBI_9774

AHFScode

12:20.00

ATCCode

M03AA04

M03AA02

binds

http://purl.obolibrary.org/obo/dinto_1021

http://purl.obolibrary.org/obo/dinto_1979

http://purl.obolibrary.org/obo/dinto_2747

http://purl.obolibrary.org/obo/dinto_1123

http://purl.obolibrary.org/obo/dinto_1970

blocks

http://purl.obolibrary.org/obo/dinto_2747

http://purl.obolibrary.org/obo/dinto_1123

CASRN

6989-98-6

DBBrand

jexin

tubarine

curare

delacurarine

DBname

tubocurarine

DBSynonym

d-tubocurarine

d-tubocurarine chloride

tubocurarin

tubocurarinum

tubocurarine chloride

isoquinoline alkaloid

Definition

A benzylisoquinoline alkaloid muscle relaxant which constitutes the active component of curare.

has pharmacological target

http://purl.obolibrary.org/obo/dinto_2747

http://purl.obolibrary.org/obo/dinto_1123

has role

http://purl.obolibrary.org/obo/CHEBI_51371

http://purl.obolibrary.org/obo/CHEBI_48878

InChI

InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-37-35-25(20-34(43-5)36(37)41)13-15-39(2,3)29(35)17-23-8-11-30(40)31(18-23)45-33/h6-11,18-21,28-29H,12-17H2,1-5H3,(H-,40,41)/p+1/t28-,29+/m0/s1

InChIKey

InChIKey=JFJZZMVDLULRGK-URLMMPGGSA-O

inhibits

http://purl.obolibrary.org/obo/dinto_1021

is substrate of

http://purl.obolibrary.org/obo/dinto_1970

is transported by

http://purl.obolibrary.org/obo/dinto_1970

label

tubocurarine

may interact with

http://purl.obolibrary.org/obo/dinto_DB01303

http://purl.obolibrary.org/obo/CHEBI_2948

http://purl.obolibrary.org/obo/CHEBI_8107

http://purl.obolibrary.org/obo/dinto_DB01223

http://purl.obolibrary.org/obo/dinto_DB01627

http://purl.obolibrary.org/obo/dinto_DB01190

http://purl.obolibrary.org/obo/dinto_DB00798

http://purl.obolibrary.org/obo/CHEBI_3387

http://purl.obolibrary.org/obo/dinto_DB00955

http://purl.obolibrary.org/obo/dinto_DB00684

http://purl.obolibrary.org/obo/CHEBI_50667

http://purl.obolibrary.org/obo/CHEBI_2637

http://purl.obolibrary.org/obo/dinto_DB01320

http://purl.obolibrary.org/obo/CHEBI_28177

http://purl.obolibrary.org/obo/CHEBI_8232

modulates

http://purl.obolibrary.org/obo/dinto_2747

http://purl.obolibrary.org/obo/dinto_1123

prefixIRI

obo2:CHEBI_9774

prefLabel

tubocurarine

related with

http://purl.obolibrary.org/obo/dinto_1979

SMILES

[H][C@@]12CC3=CC=C(OC4=C5C(CC[N+](C)(C)[C@]5([H])CC5=CC(OC6=C(OC)C=C(CCN1C)C2=C6)=C(O)C=C5)=CC(OC)=C4O)C=C3

[H][C@]12Cc3ccc(Oc4c(O)c(OC)cc5CC[N+](C)(C)[C@]([H])(Cc6ccc(O)c(Oc7cc1c(CCN2C)cc7OC)c6)c45)cc3

Synonym

d-tubocurarine

C37H41N2O6

7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraran-2'-ium

7',12'-dihydroxy-6,6'-dimethoxy-2,2',2'-trimethyltubocuraranium

Tubocurarin

Tubocurarine

(1S,16R)-9,21-dihydroxy-10,25-dimethoxy-15,15,30-trimethyl-7,23-dioxa-15,30-diazaheptacyclo[22.6.2.2^{3,6}.1^{8,12}.1^{18,22}.0^{27,31}.0^{16,34}]hexatriaconta-3,5,8,10,12(34),18(33),19,21,24(32),25,27(31),35-dodecaen-15-ium

(+)-tubocurarine

xref

Beilstein:3898737

Wikipedia:http://en.wikipedia.org/wiki/Tubocurarine

ChemSpider:5778

Drugs Product Database (DPD):640786

CiteXplore:2215478

Wikipedia:Tubocurarine_chloride

PubChem Compound:6000

ChEMBL:303627

ChEBI:9774

CiteXplore:6196640

PharmGKB:PA451811

DrugBank:DB01199

CASRN:57-95-4

KEGG COMPOUND:C07547

PubChem Substance:46505279

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

Delete Subject Author Type Created
No notes to display
Create mapping

Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_9774 DOID SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 HHEAR SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_9774 DOID LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 DRON LOOM
http://purl.obolibrary.org/obo/OMIT_0015239 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.092.877.922 RH-MESH LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Tubocurarine APAONTO LOOM
http://www.drugbank.ca/drugs/DB01199 FTC LOOM
http://www.co-ode.org/ontologies/galen#Tubocurarine GALEN LOOM
http://purl.bioontology.org/ontology/CSP/2530-4485 CRISP LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D014403 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373486008 SNOMEDCT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0041345 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.098.916 RH-MESH LOOM
http://purl.jp/bio/4/id/200906082456168488 IOBC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016046 PMAPP-PMO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.531.085.944 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 HHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9774 NIFSTD LOOM
https://go.drugbank.com/drugs/DB01199 MDM LOOM
http://purl.bioontology.org/ontology/RCD/x01G0 RCD LOOM
http://purl.obolibrary.org/obo/MESH_D014403 BERO LOOM
http://purl.bioontology.org/ontology/RXNORM/10917 RXNORM LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#12652 OCHV LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148050 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.531.820.875 RH-MESH LOOM
http://purl.bioontology.org/ontology/ATC/M03AA02 ATC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.675.276.922 RH-MESH LOOM
http://purl.bioontology.org/ontology/VANDF/4019965 VANDF LOOM
http://purl.bioontology.org/ontology/MESH/D014403 MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-68760 SNMI LOOM