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The Drug-Drug Interactions Ontology
| Preferred Name | sotalol hydrochloride | |
| Synonyms |
N-isopropyl-beta-(4-methanesulfonamidophenyl)ethanolamine hydrochloride C12H20N2O3S 4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide hydrochloride sotalol HCl Betapace AF sotalol monohydrochloride 4-(2-Isopropylamino-1-hydroxyaethyl)methanesulfonailid hydrochlorid N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide isopropylaminohydroxyethylmethanesulfonanilide hydrochloride N-(2-hydroxy-2-{4-[(methylsulfonyl)amino]phenyl}ethyl)propan-2-aminium chloride C12H21ClN2O3S Betapace |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_9207 |
|
| AHFScode |
24:24.00
|
|
| ATCCode |
C07AA57 C07AA07
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|
| binds |
http://purl.obolibrary.org/obo/dinto_3187 |
|
| blocks | ||
| CASRN |
3930-20-9
|
|
| DBBrand |
betapace betapace af sorine
|
|
| DBname |
sotalol
|
|
| DBSynonym |
sotalol hcl
|
|
| Definition |
A hydrochloride salt that is the monohydrochloride of sotalol. It has both beta-adrenoreceptor blocking (Vaughan Williams Class II) and cardiac action potential duration prolongation (Vaughan Williams Class III) antiarrhythmic properties. It is used (usually as the hydrochloride salt) for the management of ventricular and supraventricular arrhythmias.
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|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000497 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001437 http://purl.obolibrary.org/obo/OAE_0001045 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000493 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0001319 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0000643 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0001403 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001465 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000358 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_2907 |
|
| has role | ||
| InChI |
InChI=1S/C12H20N2O3S/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17/h4-7,9,12-15H,8H2,1-3H3 InChI=1S/C12H20N2O3S.ClH/c1-9(2)13-8-12(15)10-4-6-11(7-5-10)14-18(3,16)17;/h4-7,9,12-15H,8H2,1-3H3;1H
|
|
| InChIKey |
InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N InChIKey=VIDRYROWYFWGSY-UHFFFAOYSA-N
|
|
| inhibits | ||
| label |
sotalol hydrochloride
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|
| modulates | ||
| prefixIRI |
obo2:CHEBI_9207
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|
| prefLabel |
sotalol hydrochloride
|
|
| SMILES |
CC(C)NCC(O)C1=CC=C(NS(C)(=O)=O)C=C1 Cl.CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1
|
|
| Synonym |
N-isopropyl-beta-(4-methanesulfonamidophenyl)ethanolamine hydrochloride C12H20N2O3S 4'-(1-hydroxy-2-(isopropylamino)ethyl)methanesulfonanilide monohydrochloride N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide hydrochloride sotalol HCl Betapace AF sotalol monohydrochloride 4-(2-Isopropylamino-1-hydroxyaethyl)methanesulfonailid hydrochlorid N-(4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}phenyl)methanesulfonamide isopropylaminohydroxyethylmethanesulfonanilide hydrochloride N-(2-hydroxy-2-{4-[(methylsulfonyl)amino]phenyl}ethyl)propan-2-aminium chloride C12H21ClN2O3S Betapace
|
|
| xref |
KEGG DRUG:D01026 PubChem Substance:46505012 National Drug Code Directory:0245-0012-11 Reaxys:4279514 RxList:http://www.rxlist.com/cgi/generic/betapaceaf.htm Drugs.com:http://www.drugs.com/cdi/sotalol.html Drugs Product Database (DPD):2257858 PharmGKB:PA451457 Wikipedia:http://en.wikipedia.org/wiki/Sotalol KEGG COMPOUND:C08229 ChEMBL:646564 DrugBank:DB00489 CASRN:959-24-0 BindingDB:25762 PubChem Compound:5253 ChemSpider:5063
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| subClassOf |
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