| Synonyms |
cis-(+)-sertraline
(1S,4S)-sertraline
sertraline
sertralinum
(1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
sertralina
Sertraline
C17H17Cl2N
CP 51974
(1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
(+)-sertraline
|
|
| Definition |
A member of the class of tetralins that is tetralin which is substituted at positions 1 and 4 by a methylamino and a 3,4-dichlorophenyl group, respectively (the S,S diastereoisomer). A selective serotonin-reuptake inhibitor (SSRI), it is administered orally as the hydrochloride salt as an antidepressant for the treatment of depression, obsessive-compulsive disorder, panic disorder and post-traumatic stress disorder.
|
|
| InChI |
InChI=1S/C17H17Cl2N/c1-20-17-9-7-12(13-4-2-3-5-14(13)17)11-6-8-15(18)16(19)10-11/h2-6,8,10,12,17,20H,7,9H2,1H3/t12-,17-/m0/s1
|
|
| Synonym |
cis-(+)-sertraline (1S,4S)-sertraline sertraline sertralinum (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine sertralina Sertraline C17H17Cl2N CP 51974 (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine (+)-sertraline
|
|
| xref |
CASRN:79617-96-2 CiteXplore:19502000 HMDB:HMDB05010 PharmGKB:PA451333 KEGG COMPOUND:C07246 Patent:US4536518 ChEBI:9123 RxList:http://www.rxlist.com/cgi/generic/sertral.htm Reaxys:5753709 DrugBank:DB01104 ChemSpider:61881 National Drug Code Directory:0049-4960-30 KEGG DRUG:D02360 Drugs Product Database (DPD):2245749 CiteXplore:21823671 CASRN:5753709 Drugs.com:http://www.drugs.com/sertraline.html NIST Chemistry WebBook:79617-96-2 PubChem Substance:46505341 ChEMBL:153616 Wikipedia:http://en.wikipedia.org/wiki/Sertraline Wikipedia:Sertraline PubChem Compound:68617
|
|