The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	prazosin
Synonyms	2-[4-(2-furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine prazosine prazosinum prazosin 2-{4-[(furan-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline prazosina 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine C19H21N5O4
ID	http://purl.obolibrary.org/obo/CHEBI_8364
AHFScode	24:20.00
ATCCode	C02CA01
blocks	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_0234
CASRN	19216-56-9
DBBrand	lentopres minipress vasoflex minipress xl furazosin
DBname	prazosin
DBSynonym	prazocin prazosina [inn-spanish] prazosin hydrochloride prazosin hcl prazosinum [inn-latin] prazosine [inn-french]
Definition	A piperazine that has formula C19H21N5O4.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000473 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000242 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_4020 http://purl.obolibrary.org/obo/dinto_3475 http://purl.obolibrary.org/obo/dinto_0234
has role	http://purl.obolibrary.org/obo/CHEBI_37890 http://purl.obolibrary.org/obo/CHEBI_35674
InChI	InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)
InChIKey	InChIKey=IENZQIKPVFGBNW-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1972 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_0140 http://purl.obolibrary.org/obo/dinto_3187 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_3483
is metabolised by	http://purl.obolibrary.org/obo/dinto_0269
is transported by	http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_0883 http://purl.obolibrary.org/obo/dinto_1440
label	prazosin
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/CHEBI_9948 http://purl.obolibrary.org/obo/CHEBI_4551 http://purl.obolibrary.org/obo/CHEBI_71940 http://purl.obolibrary.org/obo/CHEBI_3437 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/CHEBI_70746 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/CHEBI_63622 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/CHEBI_238698 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/dinto_DB01359 http://purl.obolibrary.org/obo/CHEBI_6904 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/CHEBI_9398 http://purl.obolibrary.org/obo/CHEBI_2379 http://purl.obolibrary.org/obo/CHEBI_3082 http://purl.obolibrary.org/obo/dinto_DB01580 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/CHEBI_6343 http://purl.obolibrary.org/obo/CHEBI_258351 http://purl.obolibrary.org/obo/CHEBI_46295
prefixIRI	obo2:CHEBI_8364
prefLabel	prazosin
related with	http://purl.obolibrary.org/obo/dinto_3582
SMILES	COC1=C(OC)C=C2C(N)=NC(=NC2=C1)N1CCN(CC1)C(=O)C1=CC=CO1 COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1
Synonym	2-[4-(2-furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-amine prazosine prazosinum prazosin 2-{4-[(furan-2-yl)carbonyl]piperazin-1-yl}-6,7-dimethoxyquinazolin-4-amine 2-(4-(2-Furoyl)piperazin-1-yl)-4-amino-6,7-dimethoxyquinazoline prazosina 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylcarbonyl)piperazine C19H21N5O4
xref	Guide To Pharmacology:503 RxList:http://www.rxlist.com/cgi/generic3/prazosin.htm Patent:NL7206067 ChemSpider:4724 KEGG COMPOUND:C07368 Beilstein:768345 Wikipedia:Prazosin PubChem Substance:46508594 ChEMBL:100097 Patent:GB1156973 PharmGKB:PA451093 BindingDB:29568 ChEBI:8364 Drugs Product Database (DPD):1910302 CASRN:19216-56-9 Wikipedia:http://en.wikipedia.org/wiki/Prazosin PubChem Compound:4893 IUPHAR:503 National Drug Code Directory:0069-4310-71 Patent:US3511836 DrugBank:DB00457 Drugs.com:http://www.drugs.com/cdi/prazosin.html
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_8364	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8364	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	CHEBI	LOOM
http://purl.bioontology.org/ontology/RXNORM/8629	RXNORM	LOOM
https://bioportal.bioontology.org/ontologies/STMSO#Prazosin	STMSO	LOOM
http://www.co-ode.org/ontologies/galen#Prazosin	GALEN	LOOM
http://purl.bioontology.org/ontology/LNC/LP18588-1	LOINC	LOOM
http://purl.obolibrary.org/obo/MESH_D011224	BERO	LOOM
https://go.drugbank.com/drugs/DB00457	MDM	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147986	OCVDAE	LOOM
http://purl.bioontology.org/ontology/CSP/2332-2455	CRISP	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#10030	OCHV	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387433003	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/RCD/x01CR	RCD	LOOM
http://purl.obolibrary.org/obo/OMIT_0012188	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.786.750	RH-MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017876	PMAPP-PMO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C767	NCIT	LOOM
http://purl.bioontology.org/ontology/MESH/D011224	MESH	LOOM
http://www.drugbank.ca/drugs/DB00457	FTC	LOOM
http://purl.bioontology.org/ontology/VANDF/4019901	VANDF	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D011224	RH-MESH	LOOM
http://purl.bioontology.org/ontology/SNMI/C-81635	SNMI	LOOM
http://purl.obolibrary.org/obo/NCIT_C767	BERO	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147986	NDFRT	LOOM
http://stirdf.jst.go.jp/id/200907077485472331	IOBC	LOOM
http://purl.jp/bio/4/id/200906075301182275	IOBC	LOOM
http://bmi.utah.edu/ontologies/hfontology/C0032912	HFO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0032912	OCHV	LOOM
http://purl.bioontology.org/ontology/NDDF/004491	NDDF	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_8364	NIFSTD	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004704	LOINC	LOOM
http://purl.bioontology.org/ontology/ATC/C02CA01	ATC	LOOM