The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	piroxicam
Synonyms	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1$l^{6},2-benzothiazine-3-carboxamide C15H13N3O4S Piroxicam piroxicam piroxicamum 4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide Pyroxycam FELDENE Feldene
ID	http://purl.obolibrary.org/obo/CHEBI_8249
AHFScode	28:08.04.92
ATCCode	M01AC01 S01BC06 M02AA07
binds	http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_2116 http://purl.obolibrary.org/obo/dinto_0217
CASRN	36322-90-4
DBBrand	akten riacen feldene flogobene bruxicam larapam improntal geldene piroxicam usp baxo roxicam artroxicam erazon caliment pipoxicam sasulen pirkam roxiden zunden apo-piroxicam solocalm reudene piroflex
DBname	piroxicam
DBSynonym	ak1015
Definition	A benzothiazine that has formula C15H13N3O4S.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0001238 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000687 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000438 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0001209 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2116
has role	http://purl.obolibrary.org/obo/CHEBI_35544 http://purl.obolibrary.org/obo/CHEBI_35480 http://purl.obolibrary.org/obo/CHEBI_35475 http://purl.obolibrary.org/obo/CHEBI_50630
InChI	InChI=1S/C15H13N3O4S/c1-18-13(15(20)17-12-8-4-5-9-16-12)14(19)10-6-2-3-7-11(10)23(18,21)22/h2-9,19H,1H3,(H,16,17,20)
InChIKey	InChIKey=QYSPLQLAKJAUJT-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_1221 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_2116
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_1221
is substrate of	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_1221
label	piroxicam
may interact with	http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/dinto_DB08814 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_9434 http://purl.obolibrary.org/obo/CHEBI_3437 http://purl.obolibrary.org/obo/CHEBI_44185 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/CHEBI_4856 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_63622 http://purl.obolibrary.org/obo/dinto_DB00214 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_3127 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_238698 http://purl.obolibrary.org/obo/CHEBI_3441 http://purl.obolibrary.org/obo/CHEBI_59594 http://purl.obolibrary.org/obo/dinto_DB00582 http://purl.obolibrary.org/obo/CHEBI_2904 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/dinto_DB01359 http://purl.obolibrary.org/obo/CHEBI_6904 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/dinto_DB00440 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_2379 http://purl.obolibrary.org/obo/CHEBI_3082 http://purl.obolibrary.org/obo/dinto_DB01580 http://purl.obolibrary.org/obo/CHEBI_70707 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/CHEBI_71223 http://purl.obolibrary.org/obo/CHEBI_4513 http://purl.obolibrary.org/obo/dinto_DB00503 http://purl.obolibrary.org/obo/CHEBI_68845 http://purl.obolibrary.org/obo/CHEBI_6343 http://purl.obolibrary.org/obo/CHEBI_27999 http://purl.obolibrary.org/obo/dinto_DB01381 http://purl.obolibrary.org/obo/CHEBI_258351 http://purl.obolibrary.org/obo/CHEBI_2567
prefixIRI	obo2:CHEBI_8249
prefLabel	piroxicam
related with	http://purl.obolibrary.org/obo/dinto_0217
SMILES	CN1C(C(=O)NC2=NC=CC=C2)=C(O)C2=C(C=CC=C2)S1(=O)=O CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O
Synonym	4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazin-3-caboxyamid-1,1-dioxid 4-hydroxy-2-methyl-1,1-dioxo-N-(pyridin-2-yl)-2H-1$l^{6},2-benzothiazine-3-carboxamide C15H13N3O4S Piroxicam piroxicam piroxicamum 4-hydroxy-2-methyl-N-pyridin-2-yl-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide Pyroxycam FELDENE Feldene
xref	KEGG COMPOUND:C01608 Beilstein:627692 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/fel1173.shtml CASRN:36322-90-4 Drugs.com:http://www.drugs.com/cdi/piroxicam.html Patent:US3591584 Wikipedia:Piroxicam ChEMBL:111968 RxList:http://www.rxlist.com/cgi/generic/piroxicam.htm DrugBank:DB00554 National Drug Code Directory:0378-1010-01 Reaxys:627692 Wikipedia:http://en.wikipedia.org/wiki/Piroxicam ChEBI:8249 NIST Chemistry WebBook:36322-90-4 KEGG DRUG:D00127 PharmGKB:PA450985 Patent:DE1943265 Drugs Product Database (DPD):658839
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_8249	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_8249	DRON	SAME_URI
http://purl.jp/bio/4/id/200906034077203182	IOBC	LOOM
http://www.drugbank.ca/drugs/DB00554	FTC	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C751	NCIT	LOOM
http://purl.obolibrary.org/obo/OMIT_0011868	OMIT	LOOM
http://bmi.utah.edu/ontologies/peontology/C0031990	RAO	LOOM
http://purl.bioontology.org/ontology/RCD/j2e..	RCD	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017457	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#9755	OCHV	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_8249	DRON	LOOM
http://purl.bioontology.org/ontology/RXNORM/8356	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.665.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP15181-8	LOINC	LOOM
http://www.co-ode.org/ontologies/galen#Piroxicam	GALEN	LOOM
http://purl.bioontology.org/ontology/ATC/S01BC06	ATC	LOOM
http://purl.obolibrary.org/obo/MESH_D010894	BERO	LOOM
http://purl.bioontology.org/ontology/ATC/M01AC01	ATC	LOOM
http://purl.bioontology.org/ontology/CSP/4001-0107	CRISP	LOOM
http://purl.bioontology.org/ontology/VANDF/4018626	VANDF	LOOM
http://purl.bioontology.org/ontology/ATC/M02AA07	ATC	LOOM
http://stirdf.jst.go.jp/id/200907093354635265	IOBC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0031990	OCHV	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387153005	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/MESH/D010894	MESH	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146939	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-60430	SNMI	LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000039761	PDQ	LOOM
https://go.drugbank.com/drugs/DB00554	MDM	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU001848	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.855.500	RH-MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C751	BERO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D010894	RH-MESH	LOOM