loading...| Preferred Name | tolmetin | |
| Synonyms |
[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid 1-Methyl-5-p-toluoylpyrrole-2-acetic acid tolmetina tolmetino 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid tolmetine tolmetinum tolmetin 2-{1-methyl-5-[(4-methylphenyl)carbonyl]-1H-pyrrol-2-yl}acetic acid C15H15NO3 |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_71941 |
|
| altId |
CHEBI:9618 |
|
| ATCCode |
M02AA21 M01AB03 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_0297 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0520 |
|
| CASRN |
26171-23-3 |
|
| DBBrand |
tolectin tolectin ds |
|
| DBname |
tolmetin |
|
| DBSynonym |
tolmetine [inn-french] tolmetina [dcit] tolmetinum [inn-latin] tolmetin sodium tolmetino [inn-spanish] |
|
| Definition |
A monocarboxylic acid that is (1-methylpyrrol-2-yl)acetic acid substituted at position 5 on the pyrrole ring by a 4-methylbenzoyl group. Used in the form of its sodium salt dihydrate as a nonselective nonsteroidal anti-inflammatory drug. |
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C15H15NO3/c1-10-3-5-11(6-4-10)15(19)13-8-7-12(16(13)2)9-14(17)18/h3-8H,9H2,1-2H3,(H,17,18) |
|
| InChIKey |
InChIKey=UPSPUYADGBWSHF-UHFFFAOYSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_0297 http://purl.obolibrary.org/obo/dinto_0938 http://purl.obolibrary.org/obo/dinto_0520 |
|
| label |
tolmetin |
|
| prefixIRI |
obo2:CHEBI_71941 |
|
| prefLabel |
tolmetin |
|
| SMILES |
CN1C(CC(O)=O)=CC=C1C(=O)C1=CC=C(C)C=C1 Cc1ccc(cc1)C(=O)c1ccc(CC(O)=O)n1C |
|
| Synonym |
[1-methyl-5-(4-methylbenzoyl)-1H-pyrrol-2-yl]acetic acid 5-(p-Toluoyl)-1-methylpyrrole-2-acetic acid 1-Methyl-5-p-toluoylpyrrole-2-acetic acid tolmetina tolmetino 1-Methyl-5-(4-methylbenzoyl)-pyrrole-2-acetic acid tolmetine tolmetinum tolmetin 2-{1-methyl-5-[(4-methylphenyl)carbonyl]-1H-pyrrol-2-yl}acetic acid C15H15NO3 |
|
| xref |
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/tol1449.shtml CiteXplore:1206489 CiteXplore:19181568 RxList:http://www.rxlist.com/cgi/generic2/tolmetin.htm CiteXplore:8472518 CiteXplore:22005020 KEGG COMPOUND:C07149 Patent:WO2008017903 DrugBank:DB00500 HMDB:HMDB14643 Wikipedia:Tolmetin CiteXplore:20529813 CiteXplore:22943177 Patent:WO2004069782 ChemSpider:5308 PDBeChem:TLT PubChem Substance:46507060 ChEMBL:218617 Patent:DE2836902 PharmGKB:PA451721 CiteXplore:21936545 PubChem Compound:5509 NIST Chemistry WebBook:26171-23-3 CiteXplore:23333829 CiteXplore:19505209 CiteXplore:20853464 Drugs.com:http://www.drugs.com/cdi/tolmetin.html Drugs Product Database (DPD):632740 CiteXplore:20582193 National Drug Code Directory:0093-8815-01 Reaxys:485305 Wikipedia:http://en.wikipedia.org/wiki/Tolmetin CiteXplore:6686452 CiteXplore:445955 CASRN:26171-23-3 Patent:MX2010012712 Patent:WO2009072139 KEGG DRUG:D02355 CiteXplore:3390998 |
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| subClassOf |