The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

pitavastatin calcium
Synonyms

C50H46CaF2N2O8

Pitavastatin hemicalcium

calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate}

Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate) monocalcium salt
ID

http://purl.obolibrary.org/obo/CHEBI_71258
Definition

The calcium salt of pitavastatin. Used for treatment of hypercholesterolemia (elevated levels of cholesterol in the blood) on patients unable to sufficiently lower their cholesterol levels by diet and exercise.
has role

http://purl.obolibrary.org/obo/CHEBI_35664

http://purl.obolibrary.org/obo/CHEBI_22586

http://purl.obolibrary.org/obo/CHEBI_35821
InChI

InChI=1S/2C25H24FNO4.Ca/c2*26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31;/h2*1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31);/q;;+2/p-2/b2*12-11+;/t2*18-,19-;/m11./s1
InChIKey

InChIKey=RHGYHLPFVJEAOC-FFNUKLMVSA-L
label

pitavastatin calcium
prefixIRI

obo2:CHEBI_71258
prefLabel

pitavastatin calcium
SMILES

[Ca++].O[C@H](C[C@H](O)\\C=C\\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O.O[C@H](C[C@H](O)\\C=C\\c1c(nc2ccccc2c1-c1ccc(F)cc1)C1CC1)CC([O-])=O
Synonym

C50H46CaF2N2O8

Pitavastatin hemicalcium

calcium bis{(3R,5S,6E)-7-[2-cyclopropyl-4-(4-fluorophenyl)quinolin-3-yl]-3,5-dihydroxyhept-6-enoate}

Bis((3R,5S,6E)-7-(2-cyclopropyl-4-(4-fluorophenyl)-3-quinolyl)-3,5-dihydroxy-6-heptenoate) monocalcium salt
xref

Patent:US2009182008

Patent:KR20110092804

Wikipedia:Pitavastatin

CiteXplore:21816477

Patent:WO2012025939

Patent:WO2007132482

CiteXplore:21381428

ChEMBL:799412

CiteXplore:20621877

CiteXplore:21225019

Patent:WO2011105649

CiteXplore:21069103

Patent:WO2007125547

CASRN:147526-32-7

Patent:WO2005063711

Patent:US2011319624

CiteXplore:20852754

Patent:KR20110097058

CiteXplore:21651447

CiteXplore:20664824

Patent:US2011082298

Patent:US2012016129

KEGG DRUG:D01862

Patent:EP2383260

Patent:WO2012002741

Reaxys:7965530

Patent:US2012101126
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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