loading...| Preferred Name |
desoximetasone |
|
| Synonyms |
desoximetasona desoximetasonum desoximetasone 9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione desoxymethasone C22H29FO4 (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_691037 |
|
| activates | ||
| AHFScode |
84:06.00 |
|
| ATCCode |
D07XC02 D07AC03 |
|
| binds | ||
| CASRN |
382-67-2 |
|
| DBBrand |
topicort topicort lp |
|
| DBname |
desoximetasone |
|
| Definition |
Dexamethasone in which the hydroxy group at the 17alpha position is substituted by hydrogen. A synthetic corticosteroid with glucocorticoid activity, it is used as an anti-inflammatory and anti-pruritic in the treatment of various skin disorders, including skin allergies and psoriasis. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000489 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000086 |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C22H29FO4/c1-12-8-16-15-5-4-13-9-14(25)6-7-21(13,3)22(15,23)18(27)10-20(16,2)19(12)17(26)11-24/h6-7,9,12,15-16,18-19,24,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,18+,19-,20+,21+,22+/m1/s1 |
|
| InChIKey |
InChIKey=VWVSBHGCDBMOOT-IIEHVVJPSA-N |
|
| label |
desoximetasone |
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_691037 |
|
| prefLabel |
desoximetasone |
|
| SMILES |
[H][C@@]12C[C@@H](C)[C@H](C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |
|
| Synonym |
desoximetasona desoximetasonum desoximetasone 9-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione desoxymethasone C22H29FO4 (1R,2S,10S,11S,13R,14S,15S,17S)-1-fluoro-17-hydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one 9alpha-fluoro-16alpha-methyl-Delta(1)-corticosterone (11beta,16alpha)-9-fluoro-11,21-dihydroxy-16-methylpregna-1,4-diene-3,20-dione |
|
| xref |
KEGG DRUG:D03697 ChEBI:691037 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/top1452.shtml Drugs Product Database (DPD):2241887 Patent:US3232839 CASRN:382-67-2 Drugs.com:http://www.drugs.com/cdi/desoximetasone-cream.html PharmGKB:PA164746011 DrugBank:DB00547 RxList:http://www.rxlist.com/cgi/generic3/desoximeta.htm National Drug Code Directory:51672-1271-1 Beilstein:2228097 Patent:FR1296544 ChemSpider:4470604 Wikipedia:Desoximetasone Patent:US3099654 Patent:BE314196 PubChem Substance:46506793 PubChem Compound:5311067 |
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| subClassOf |