| Synonyms |
7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide
Zaroxolyn
C16H16ClN3O3S
7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide
7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide
metolazona
metolazone
2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone
metolazonum
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| Definition |
A quinazoline that consists of 1,2,3,4-tetrahydroquinazolin-4-one bearing additional methyl, 2-tolyl, sulfamyl and chloro substituents at positions 2, 3, 6 and 7 respectively. A quinazoline diuretic, with properties similar to thiazide diuretics.
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| InChI |
InChI=1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)
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| Synonym |
7-Chloro-1,2,3,4-tetrahydro-2-methyl-4-oxo-3-o-tolyl-6-quinazolinesulfonamide Zaroxolyn C16H16ClN3O3S 7-Chloro-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-quinazolinesulfonamide 7-chloro-2-methyl-3-(2-methylphenyl)-4-oxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide metolazona metolazone 2-Methyl-3-o-tolyl-6-sulfamyl-7-chloro-1,2,3,4-tetrahydro-4-quinazolinone metolazonum
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| xref |
PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zar1495.shtml PubChem Compound:4170 CiteXplore:12671341 Drugs.com:http://www.drugs.com/cdi/metolazone.html NIST Chemistry WebBook:17560-51-9 CiteXplore:21886902 Patent:US2008139593 CiteXplore:1886511 DrugBank:DB00524 CASRN:17560-51-9 CiteXplore:15095363 National Drug Code Directory:0378-6172-01 CiteXplore:9089428 PubChem Substance:46509058 Drugs Product Database (DPD):888400 Reaxys:965506 CiteXplore:16717105 CiteXplore:1946137 CiteXplore:16908225 CiteXplore:16538931 CiteXplore:16189620 Wikipedia:Metolazone ChemSpider:4026 KEGG DRUG:D00431 CiteXplore:1593359 Wikipedia:http://en.wikipedia.org/wiki/Metolazone ChEMBL:173548 CiteXplore:8205244 BindingDB:25899 CiteXplore:2071258 Patent:US3360518 RxList:http://www.rxlist.com/cgi/generic2/metolazone.htm PharmGKB:PA164781022 CiteXplore:8870895 CiteXplore:21387350 CiteXplore:8199745 CiteXplore:1928234
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