B01AC11

78919-13-8

ventavis

iloprost

A carbobicyclic compound that is prostaglandin I2 in which the endocyclic oxygen is replaced by a methylene group and in which the (1E,3S)-3-hydroxyoct-1-en-1-yl side chain is replaced by a (3R)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl group. A synthetic analogue of prostacyclin, it is used as the trometamol salt (generally by intravenous infusion) for the treatment of peripheral vascular disease and pulmonary hypertension.

InChI=1S/C22H32O4/c1-3-4-7-15(2)20(23)11-10-18-19-13-16(8-5-6-9-22(25)26)12-17(19)14-21(18)24/h8,10-11,15,17-21,23-24H,5-7,9,12-14H2,1-2H3,(H,25,26)/b11-10+,16-8+/t15?,17-,18+,19-,20+,21+/m0/s1

InChI=1S/C30H38O5/c1-3-4-10-21(2)27(31)16-15-25-26-18-22(17-24(26)19-28(25)32)11-8-9-14-30(34)35-20-29(33)23-12-6-5-7-13-23/h5-7,11-13,15-16,21,24-28,31-32H,8-10,14,17-20H2,1-2H3/b16-15+,22-11-

InChIKey=HIFJCPQKFCZDDL-ACWOEMLNSA-N

InChIKey=CZUMMMDKQYRZDP-JCAXBLPDSA-N

iloprost

obo2:CHEBI_63916

iloprost

[H][C@]1(\\C=C\\[C@@H](O)C(C)CC#CC)[C@H](O)C[C@@H]2C\\C(C[C@H]12)=C/CCCC(O)=O

CC#CCC(C)C(O)\C=C\C1C(O)CC2C\C(CC12)=C\CCCC(=O)OCC(=O)C1=CC=CC=C1

iloprostum

iloprost

C22H32O4

(16R,S)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandin I2

(5E)-5-[(3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]hexahydropentalen-2(1H)-ylidene]pentanoic acid

2-oxo-2-phenylethyl 5-[(2Z)-5-hydroxy-4-[(1E)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoate

C30H38O5

Patent:US4692464

ChEMBL:107494

KEGG DRUG:D02721

PharmGKB:PA164746843

Wikipedia:http://en.wikipedia.org/wiki/Iloprost

National Drug Code Directory:66215-302-30

ChemSpider:4947911

Reaxys:4329060

PubChem Compound:6443959

DrugBank:DB01088

CiteXplore:14719835

RxList:http://www.rxlist.com/cgi/generic4/ventavis.htm

CASRN:78919-13-8

PubChem Substance:46507818

Drugs.com:http://www.drugs.com/cdi/iloprost.html

Patent:DE2845770

CiteXplore:15232651

CiteXplore:15241524

Wikipedia:Iloprost

CiteXplore:19436672