loading...| Preferred Name |
latanoprost |
|
| Synonyms |
C26H40O5 isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate latanoprostum latanoprost propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate PhXA 41 propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate Xalatan |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_6384 |
|
| activates | ||
| AHFScode |
52:92.00 |
|
| ATCCode |
S01EE01 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_1970 |
|
| CASRN |
130209-82-4 |
|
| DBBrand |
xalatan fixed flow device xalatan |
|
| DBname |
latanoprost |
|
| Definition |
A prostaglandin Falpha that is the isopropyl ester prodrug of latanoprost free acid. Used in the treatment of open-angle glaucoma and ocular hypertension. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000312 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0001382 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000329 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_39456 http://purl.obolibrary.org/obo/CHEBI_35674 |
|
| InChI |
InChI=1S/C26H40O5/c1-19(2)31-26(30)13-9-4-3-8-12-22-23(25(29)18-24(22)28)17-16-21(27)15-14-20-10-6-5-7-11-20/h3,5-8,10-11,19,21-25,27-29H,4,9,12-18H2,1-2H3/b8-3-/t21-,22+,23+,24-,25+/m0/s1 |
|
| InChIKey |
InChIKey=GGXICVAJURFBLW-CEYXHVGTSA-N |
|
| is substrate of | ||
| is transported by | ||
| label |
latanoprost |
|
| may interact with | ||
| modulates | ||
| prefixIRI |
obo2:CHEBI_6384 |
|
| prefLabel |
latanoprost |
|
| related with | ||
| SMILES |
CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCC1=CC=CC=C1 CC(C)OC(=O)CCC\\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1CC[C@@H](O)CCc1ccccc1 |
|
| Synonym |
C26H40O5 isopropyl (5Z,9alpha,11alpha,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-en-1-oate latanoprostum latanoprost propan-2-yl (5Z)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl}hept-5-enoate PhXA 41 propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate isopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate Xalatan |
|
| xref |
CiteXplore:22289196 CiteXplore:22320418 CiteXplore:21278589 KEGG DRUG:D00356 CiteXplore:22275828 Wikipedia:http://en.wikipedia.org/wiki/Latanoprost Wikipedia:Latanoprost CiteXplore:21858678 CiteXplore:22323882 National Drug Code Directory:0013-8303-01 HMDB:HMDB14792 RxList:http://www.rxlist.com/cgi/generic/latanoprost.htm CiteXplore:22275814 BindingDB:50150899 CiteXplore:22167539 Beilstein:5912370 CiteXplore:22040280 CiteXplore:22289195 Reaxys:5912370 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/xal1490.shtml PharmGKB:PA164774763 Drugs.com:http://www.drugs.com/cdi/latanoprost-drops.html Drugs Product Database (DPD):2231493 CiteXplore:22167538 CASRN:130209-82-4 CiteXplore:22283238 CiteXplore:22049909 ChEBI:6384 DrugBank:DB00654 |
|
| subClassOf |