The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Preferred Name	rasagiline
Synonyms	(1R)-N-(prop-2-yn-1-yl)indan-1-amine (R)-N-2-Propynyl-1-indanamine (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine (1R)-N-propargylindan-1-amine rasagiline RAS (R)-indan-1-yl-prop-2-ynyl-amine C12H13N
ID	http://purl.obolibrary.org/obo/CHEBI_63620
AHFScode	28:92.00
ATCCode	N04BD02
binds	http://purl.obolibrary.org/obo/dinto_3622 http://purl.obolibrary.org/obo/dinto_2099 http://purl.obolibrary.org/obo/dinto_2651
CASRN	136236-51-6
DBBrand	azilect
DBname	rasagiline
DBSynonym	ras
Definition	An indane that consists of 1-aminoindane bearing an N-propargyl substituent. A selective, irreversible monoamine oxidase-B inhibitor.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0001297 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0001259 http://purl.obolibrary.org/obo/OAE_0000318 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000198 http://purl.obolibrary.org/obo/OAE_0000596 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000801 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000967 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000935 http://purl.obolibrary.org/obo/OAE_0001165 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000527 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0001538 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0000386 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000283 http://purl.obolibrary.org/obo/OAE_0000691 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0000802 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0000526 http://purl.obolibrary.org/obo/OAE_0001308 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0001374 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0001341 http://purl.obolibrary.org/obo/OAE_0000510 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0000433 http://purl.obolibrary.org/obo/OAE_0000184 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0000440 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000038 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0000516 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000275 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000470 http://purl.obolibrary.org/obo/OAE_0000514 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000716 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001298 http://purl.obolibrary.org/obo/OAE_0000350
has pharmacological target	http://purl.obolibrary.org/obo/dinto_2099 http://purl.obolibrary.org/obo/dinto_3622
has role	http://purl.obolibrary.org/obo/CHEBI_38623 http://purl.obolibrary.org/obo/CHEBI_63726
InChI	InChI=1S/C12H13N/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12/h1,3-6,12-13H,7-9H2/t12-/m1/s1
InChIKey	InChIKey=RUOKEQAAGRXIBM-GFCCVEGCSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_3622
is metabolised by	http://purl.obolibrary.org/obo/dinto_2651
is substrate of	http://purl.obolibrary.org/obo/dinto_2651
label	rasagiline
prefixIRI	obo2:CHEBI_63620
prefLabel	rasagiline
related with	http://purl.obolibrary.org/obo/dinto_2099
SMILES	C#CCN[C@@H]1CCC2=CC=CC=C12 C#CCN[C@@H]1CCc2ccccc12
Synonym	(1R)-N-(prop-2-yn-1-yl)indan-1-amine (R)-N-2-Propynyl-1-indanamine (1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine (1R)-N-propargylindan-1-amine rasagiline RAS (R)-indan-1-yl-prop-2-ynyl-amine C12H13N
xref	KEGG DRUG:D08469 CiteXplore:21864207 DrugBank:DB01367 CiteXplore:22045282 Drugs.com:http://www.drugs.com/cdi/rasagiline.html PubChem Compound:3052776 Wikipedia:http://en.wikipedia.org/wiki/Rasagiline ChemSpider:2314553 Drugs Product Database (DPD):2284642 PubChem Substance:46506045 CiteXplore:21895884 CiteXplore:22065207 Reaxys:9194207 PDB:RAS CiteXplore:21953831 National Drug Code Directory:68546-142-56 CiteXplore:21500280 BindingDB:10989 CiteXplore:21482191 CiteXplore:21671840 RxList:http://www.rxlist.com/cgi/generic/azilect.htm PharmGKB:PA164764584 CiteXplore:21971007 Wikipedia:Rasagiline CiteXplore:21819487 CiteXplore:21946113 CiteXplore:21878836 CiteXplore:21971006 CASRN:136236-51-6 CiteXplore:20577110 CiteXplore:21628600
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_63620	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63620	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63620	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63620	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63620	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_63620	DRON	SAME_URI
https://go.drugbank.com/drugs/DB01367	MDM	LOOM
http://www.semanticweb.org/ontologies/2011/1/Ontology1296772722296.owl#EPO_00000085	PDON	LOOM
http://purl.bioontology.org/ontology/ATC/N04BD02	ATC	LOOM
http://stirdf.jst.go.jp/id/200907020073042152	IOBC	LOOM
http://purl.bioontology.org/ontology/MESH/C031967	MESH	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026546	PMAPP-PMO	LOOM
http://purl.bioontology.org/ontology/VANDF/4025261	VANDF	LOOM
http://purl.bioontology.org/ontology/RXNORM/134748	RXNORM	LOOM
http://www.drugbank.ca/drugs/DB01367	FTC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C031967	RH-MESH	LOOM
http://purl.bioontology.org/ontology/NDDF/010775	NDDF	LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000171790	ODAE	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/418734001	SNOMEDCT	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000171790	NDFRT	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C66510	NCIT	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0525678	OCHV	LOOM
http://purl.obolibrary.org/obo/CHEBI_63620	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63620	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63620	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_63620	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_63620	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_63620	DRON	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#38410	OCHV	LOOM
http://purl.jp/bio/4/id/200906050535030247	IOBC	LOOM
http://purl.obolibrary.org/obo/NCIT_C66510	BERO	LOOM
http://purl.obolibrary.org/obo/DRON_00016437	ODNAE	LOOM