The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

encainide hydrochloride

Synonyms

4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide hydrochloride

4-methoxy-2'-(2-(1-methyl-2-piperidyl)ethyl)benzanilide hydrochloride

2-(2-{2-[(4-methoxybenzoyl)amino]phenyl}ethyl)-1-methylpiperidinium chloride

(+-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide monohydrochloride

encainide HCl

C22H29ClN2O2

ID

http://purl.obolibrary.org/obo/CHEBI_59880

Definition

The hydrochloride salt of encainide. A class Ic antiarrhythmic, it was used for the treatment of severe or life-threatening ventricular arrhythmias, but it was associated with increased death rates in patients who had asymptomatic heart rhythm abnormalities after a recent heart attack and was withdrawn from the market.

has role

http://purl.obolibrary.org/obo/CHEBI_38070

InChI

InChI=1S/C22H28N2O2.ClH/c1-24-16-6-5-8-19(24)13-10-17-7-3-4-9-21(17)23-22(25)18-11-14-20(26-2)15-12-18;/h3-4,7,9,11-12,14-15,19H,5-6,8,10,13,16H2,1-2H3,(H,23,25);1H

InChIKey

InChIKey=OJIIZIWOLTYOBS-UHFFFAOYSA-N

label

encainide hydrochloride

prefixIRI

obo2:CHEBI_59880

prefLabel

encainide hydrochloride

SMILES

Cl.COc1ccc(cc1)C(=O)Nc1ccccc1CCC1CCCCN1C

Synonym

4-methoxy-N-{2-[2-(1-methylpiperidin-2-yl)ethyl]phenyl}benzamide hydrochloride

4-methoxy-2'-(2-(1-methyl-2-piperidyl)ethyl)benzanilide hydrochloride

2-(2-{2-[(4-methoxybenzoyl)amino]phenyl}ethyl)-1-methylpiperidinium chloride

(+-)-2'-(2-(1-methyl-2-piperidyl)ethyl)-p-anisanilide monohydrochloride

encainide HCl

C22H29ClN2O2

xref

ChEMBL:1478425

DrugBank:DB01228

Beilstein:6360008

KEGG DRUG:D03991

CASRN:66794-74-9

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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