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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | diflorasone | |
| Synonyms |
C22H28F2O5 diflorasona (1R,2S,8S,10S,11S,13S,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one 6alpha,9-difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione diflorasonum (6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione diflorasone |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_59750 |
|
| activates | ||
| ATCCode |
D07AC10
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|
| binds | ||
| CASRN |
2557-49-5
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|
| DBBrand |
florone florone e psorcon maxiflor
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|
| DBname |
diflorasone
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|
| DBSynonym |
diflorasone diacetate
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|
| Definition |
The 16beta-analogue of flumethasone. It is used as the 17,21-diacetate as a topical anti-inflammatory and antipruritic in the treatment of various skin disorders.
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|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C22H28F2O5/c1-11-6-13-14-8-16(23)15-7-12(26)4-5-19(15,2)21(14,24)17(27)9-20(13,3)22(11,29)18(28)10-25/h4-5,7,11,13-14,16-17,25,27,29H,6,8-10H2,1-3H3/t11-,13-,14-,16-,17-,19-,20-,21-,22-/m0/s1
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|
| InChIKey |
InChIKey=WXURHACBFYSXBI-XHIJKXOTSA-N
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|
| label |
diflorasone
|
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_59750
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|
| prefLabel |
diflorasone
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|
| SMILES |
[H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](F)C2=CC(=O)C=C[C@]12C
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|
| Synonym |
C22H28F2O5 diflorasona (1R,2S,8S,10S,11S,13S,14R,15S,17S)-1,8-difluoro-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,13,15-trimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-dien-5-one 6alpha,9-difluoro-11beta,17,21-trihydroxy-16beta-methylpregna-1,4-diene-3,20-dione diflorasonum (6alpha,11beta,16beta)-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione diflorasone
|
|
| xref |
National Drug Code Directory:51672-1296-1 Patent:US3557158 ChEMBL:775331 DrugBank:DB00223 Patent:GB912015 Drugs.com:http://www.drugs.com/cdi/diflorasone-diacetate-cream.html Drugs Product Database (DPD):481807 RxList:http://www.rxlist.com/cgi/generic/diflorasone.htm PharmGKB:PA164749408 Wikipedia:http://en.wikipedia.org/wiki/Diflorasone Patent:GB881334 ChEBI:59750 Patent:GB898293 CASRN:2557-49-5 Beilstein:5645455 KEGG DRUG:D07827 Wikipedia:Diflorasone
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| subClassOf |
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