The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

Details
Visualization
Notes ( 0 )
Class Mappings ( )

Preferred Name	hydromorphone
Synonyms	(1S,5R,13R,17R)-10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one Hydromorphone Hydromorfona 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one 3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one hydromorphonum (-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one Idromorfone Dimorphone Dihydromorfinon 4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone 7,8-Dihydromorphinone Dihydromorphinone 6-Deoxy-7,8-dihydro-6-oxomorphine hydromorphone C17H19NO3 hidromorfona
ID	http://purl.obolibrary.org/obo/CHEBI_5790
activates	http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960
AHFScode	28:08.08
ATCCode	N02AA03
binds	http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0265 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0938
CASRN	466-99-9
DBBrand	novolaudon paramorphan palladone dilaudid-hp laudacon dilaudid oros hymorphan dimo laudicon idromorfone dilaudid dimorphone
DBname	hydromorphone
DBSynonym	hydromorfona [spanish] dihydromorphinone hidromorfona [inn-spanish] dihydromorfinon [czech] hydromorphone hcl hydromorphon hydromorphonum [inn-latin]
Definition	A morphinane alkaloid that has formula C17H19NO3.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000496 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000395 http://purl.obolibrary.org/obo/OAE_0000901 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000597 http://purl.obolibrary.org/obo/OAE_0000604 http://purl.obolibrary.org/obo/OAE_0000888 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001437 http://purl.obolibrary.org/obo/OAE_0001045 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000839 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000479 http://purl.obolibrary.org/obo/OAE_0000659 http://purl.obolibrary.org/obo/OAE_0000492 http://purl.obolibrary.org/obo/OAE_0000617 http://purl.obolibrary.org/obo/OAE_0000267 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001167 http://purl.obolibrary.org/obo/OAE_0000807 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000443 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0000512 http://purl.obolibrary.org/obo/OAE_0000308 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0000611 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0001360 http://purl.obolibrary.org/obo/OAE_0001319 http://purl.obolibrary.org/obo/OAE_0000549 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000545 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001013 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000412 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0001370 http://purl.obolibrary.org/obo/OAE_0001069 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0001025 http://purl.obolibrary.org/obo/OAE_0000677 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000984 http://purl.obolibrary.org/obo/OAE_0000426 http://purl.obolibrary.org/obo/OAE_0000883 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000945 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0001053 http://purl.obolibrary.org/obo/OAE_0000612 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0000632 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0000300 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000517 http://purl.obolibrary.org/obo/OAE_0000455 http://purl.obolibrary.org/obo/OAE_0001234 http://purl.obolibrary.org/obo/OAE_0001101 http://purl.obolibrary.org/obo/OAE_0000084 http://purl.obolibrary.org/obo/OAE_0000671 http://purl.obolibrary.org/obo/OAE_0001050 http://purl.obolibrary.org/obo/OAE_0000911 http://purl.obolibrary.org/obo/OAE_0001295 http://purl.obolibrary.org/obo/OAE_0000526 http://purl.obolibrary.org/obo/OAE_0001190 http://purl.obolibrary.org/obo/OAE_0001070 http://purl.obolibrary.org/obo/OAE_0001068 http://purl.obolibrary.org/obo/OAE_0000309 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000587 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000586 http://purl.obolibrary.org/obo/OAE_0000772 http://purl.obolibrary.org/obo/OAE_0000494 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000842 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000184 http://purl.obolibrary.org/obo/OAE_0000533 http://purl.obolibrary.org/obo/OAE_0000542 http://purl.obolibrary.org/obo/OAE_0001363 http://purl.obolibrary.org/obo/OAE_0000674 http://purl.obolibrary.org/obo/OAE_0000243 http://purl.obolibrary.org/obo/OAE_0000864 http://purl.obolibrary.org/obo/OAE_0000473 http://purl.obolibrary.org/obo/OAE_0001004 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0001164 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0000606 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000917 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0001403 http://purl.obolibrary.org/obo/OAE_0000405 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0000898 http://purl.obolibrary.org/obo/OAE_0000647 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0001336 http://purl.obolibrary.org/obo/OAE_0000302 http://purl.obolibrary.org/obo/OAE_0000022 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000185 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000347 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001291 http://purl.obolibrary.org/obo/OAE_0000514 http://purl.obolibrary.org/obo/OAE_0001345 http://purl.obolibrary.org/obo/OAE_0000296 http://purl.obolibrary.org/obo/OAE_0000501 http://purl.obolibrary.org/obo/OAE_0001166 http://purl.obolibrary.org/obo/OAE_0000881 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0001309 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0000456 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0000885 http://purl.obolibrary.org/obo/OAE_0001044 http://purl.obolibrary.org/obo/OAE_0000277 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0001298 http://purl.obolibrary.org/obo/OAE_0000350 http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target	http://purl.obolibrary.org/obo/dinto_0760 http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960
has role	http://purl.obolibrary.org/obo/CHEBI_55322 http://purl.obolibrary.org/obo/CHEBI_35482
InChI	InChI=1S/C17H19NO3/c1-18-7-6-17-10-3-5-13(20)16(17)21-15-12(19)4-2-9(14(15)17)8-11(10)18/h2,4,10-11,16,19H,3,5-8H2,1H3/t10-,11+,16-,17-/m0/s1
InChIKey	InChIKey=WVLOADHCBXTIJK-YNHQPCIGSA-N
is metabolised by	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0265 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0938
is substrate of	http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0265 http://purl.obolibrary.org/obo/dinto_0901 http://purl.obolibrary.org/obo/dinto_0938
label	hydromorphone
may interact with	http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/dinto_DB06210 http://purl.obolibrary.org/obo/dinto_DB06274
modulates	http://purl.obolibrary.org/obo/dinto_2787 http://purl.obolibrary.org/obo/dinto_3960
prefixIRI	obo2:CHEBI_5790
prefLabel	hydromorphone
related with	http://purl.obolibrary.org/obo/dinto_0760
SMILES	[H][C@]12CCC(=O)[C@@H]3Oc4c(O)ccc5C[C@H]1N(C)CC[C@@]23c45 [H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(C)[C@]([H])(C4)[C@]1([H])CCC2=O
Synonym	(1S,5R,13R,17R)-10-hydroxy-4-methyl-12-oxa-4-azapentacyclo[9.6.1.0^{1,13}.0^{5,17}.0^{7,18}]octadeca-7(18),8,10-trien-14-one Hydromorphone Hydromorfona 4,5-Epoxy-3-hydroxy-17-methylmorphinan-6-one 3-hydroxy-17-methyl-4,5alpha-epoxymorphinan-6-one hydromorphonum (-)-(5R)-4,5-Epoxy-3-hydroxy-9alpha-methylmorphinan-6-one Idromorfone Dimorphone Dihydromorfinon 4,5alpha-Epoxy-3-hydroxy-17-methyl-6-morphinanone 7,8-Dihydromorphinone Dihydromorphinone 6-Deoxy-7,8-dihydro-6-oxomorphine hydromorphone C17H19NO3 hidromorfona
xref	Wikipedia:Dihydromorphinone National Drug Code Directory:0527-1353-01 RxList:http://www.rxlist.com/cgi/generic/hydromorphone.htm Patent:US2654756 ChEMBL:519580 Patent:US2628962 DrugBank:DB00327 PubChem Compound:5284570 Beilstein:42553 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/dil1137.shtml PharmGKB:PA449918 Drugs.com:http://www.drugs.com/cdi/hydromorphone.html CASRN:466-99-9 KEGG COMPOUND:C07042 Wikipedia:http://en.wikipedia.org/wiki/Hydromorphone PubChem Substance:46508700 ChEBI:5790 Drugs Product Database (DPD):2249936 Patent:US2649454 ChemSpider:4447624
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

Add comment

Add proposal

Subscribe to notes emails

Delete	Subject	Author	Type	Created
No notes to display

Create mapping

Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_5790	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	OBIB	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	SCDO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5790	NIFSTD	SAME_URI
https://go.drugbank.com/drugs/DB00327	MDM	LOOM
http://stirdf.jst.go.jp/id/200907088877760477	IOBC	LOOM
http://purl.bioontology.org/ontology/LNC/LP16162-7	LOINC	LOOM
http://purl.bioontology.org/ontology/SNMI/C-60670	SNMI	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU060485	LOINC	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00018037	PMAPP-PMO	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.577.249.562.450	RH-MESH	LOOM
http://purl.bioontology.org/ontology/MESH/D004091	MESH	LOOM
http://purl.obolibrary.org/obo/NCIT_C62034	BERO	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62034	NCIT	LOOM
http://purl.bioontology.org/ontology/VANDF/4019779	VANDF	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0012306	OCHV	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147870	NDFRT	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/44508008	SNOMEDCT	LOOM
http://www.co-ode.org/ontologies/galen#Hydromorphone	GALEN	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3951	OCHV	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.497.607.500	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LA28606-4	LOINC	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D004091	RH-MESH	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	OBIB	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	SCDO	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_5790	NIFSTD	LOOM
http://www.drugbank.ca/drugs/DB00327	FTC	LOOM
http://purl.jp/bio/4/id/200906018600758589	IOBC	LOOM
http://purl.bioontology.org/ontology/ATC/N02AA03	ATC	LOOM
http://purl.obolibrary.org/obo/MESH_D004091	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0005356	OMIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.723.795.576.450	RH-MESH	LOOM
http://purl.bioontology.org/ontology/RXNORM/3423	RXNORM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.686.607.500	RH-MESH	LOOM