The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

treprostinil
Synonyms

treprostinil

({(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl}oxy)acetic acid

treprostinilo

C23H34O5

2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen-5-yl]oxy}acetic acid

treprostinilum
ID

http://purl.obolibrary.org/obo/CHEBI_50861
activates

http://purl.obolibrary.org/obo/dinto_2806

http://purl.obolibrary.org/obo/dinto_1874

http://purl.obolibrary.org/obo/dinto_0168
AHFScode

24:12.92
ATCCode

B01AC21
binds

http://purl.obolibrary.org/obo/dinto_2806

http://purl.obolibrary.org/obo/dinto_1874

http://purl.obolibrary.org/obo/dinto_0168

http://purl.obolibrary.org/obo/dinto_2058
CASRN

81846-19-7
DBBrand

viveta

remodulin
DBname

treprostinil
Definition

A carboxylic acid that has formula C23H34O5.
has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000879

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0000617

http://purl.obolibrary.org/obo/OAE_0001744

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000650

http://purl.obolibrary.org/obo/OAE_0001334

http://purl.obolibrary.org/obo/OAE_0001449

http://purl.obolibrary.org/obo/OAE_0001360

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000545

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0001013

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000412

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0001268

http://purl.obolibrary.org/obo/OAE_0000382

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000300

http://purl.obolibrary.org/obo/OAE_0001340

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0000498

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000533

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0001343

http://purl.obolibrary.org/obo/OAE_0000344

http://purl.obolibrary.org/obo/OAE_0000606

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000343

http://purl.obolibrary.org/obo/OAE_0000647

http://purl.obolibrary.org/obo/OAE_0000022

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0001166

http://purl.obolibrary.org/obo/OAE_0000462

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0000618

http://purl.obolibrary.org/obo/OAE_0000402

http://purl.obolibrary.org/obo/OAE_0000350

http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target

http://purl.obolibrary.org/obo/dinto_2806

http://purl.obolibrary.org/obo/dinto_1874

http://purl.obolibrary.org/obo/dinto_0168
has role

http://purl.obolibrary.org/obo/CHEBI_55347

http://purl.obolibrary.org/obo/CHEBI_50427

http://purl.obolibrary.org/obo/CHEBI_35620

http://purl.obolibrary.org/obo/CHEBI_35674

http://purl.obolibrary.org/obo/CHEBI_35554
InChI

InChI=1S/C23H34O5/c1-2-3-4-7-17(24)9-10-18-19-11-15-6-5-8-22(28-14-23(26)27)20(15)12-16(19)13-21(18)25/h5-6,8,16-19,21,24-25H,2-4,7,9-14H2,1H3,(H,26,27)/t16-,17-,18+,19-,21+/m0/s1
InChIKey

InChIKey=PAJMKGZZBBTTOY-ZFORQUDYSA-N
is metabolised by

http://purl.obolibrary.org/obo/dinto_2058
is substrate of

http://purl.obolibrary.org/obo/dinto_2058
label

treprostinil
may interact with

http://purl.obolibrary.org/obo/CHEBI_8214

http://purl.obolibrary.org/obo/CHEBI_4466

http://purl.obolibrary.org/obo/CHEBI_64022

http://purl.obolibrary.org/obo/CHEBI_5004

http://purl.obolibrary.org/obo/dinto_DB00519

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/CHEBI_28487

http://purl.obolibrary.org/obo/CHEBI_3213

http://purl.obolibrary.org/obo/CHEBI_36791

http://purl.obolibrary.org/obo/CHEBI_9352

http://purl.obolibrary.org/obo/CHEBI_585948

http://purl.obolibrary.org/obo/dinto_DB01399

http://purl.obolibrary.org/obo/CHEBI_9434

http://purl.obolibrary.org/obo/CHEBI_3437

http://purl.obolibrary.org/obo/CHEBI_8024

http://purl.obolibrary.org/obo/dinto_DB00278

http://purl.obolibrary.org/obo/dinto_DB00384

http://purl.obolibrary.org/obo/CHEBI_32221

http://purl.obolibrary.org/obo/CHEBI_7936

http://purl.obolibrary.org/obo/CHEBI_3640

http://purl.obolibrary.org/obo/CHEBI_5959

http://purl.obolibrary.org/obo/CHEBI_16899

http://purl.obolibrary.org/obo/CHEBI_49662

http://purl.obolibrary.org/obo/CHEBI_101278

http://purl.obolibrary.org/obo/CHEBI_142290

http://purl.obolibrary.org/obo/dinto_DB01225

http://purl.obolibrary.org/obo/CHEBI_9927

http://purl.obolibrary.org/obo/CHEBI_64354

http://purl.obolibrary.org/obo/CHEBI_601027

http://purl.obolibrary.org/obo/CHEBI_6541

http://purl.obolibrary.org/obo/CHEBI_31401

http://purl.obolibrary.org/obo/CHEBI_8249

http://purl.obolibrary.org/obo/CHEBI_31547

http://purl.obolibrary.org/obo/CHEBI_3988

http://purl.obolibrary.org/obo/CHEBI_4856

http://purl.obolibrary.org/obo/dinto_DB00054

http://purl.obolibrary.org/obo/dinto_DB01021

http://purl.obolibrary.org/obo/CHEBI_8713

http://purl.obolibrary.org/obo/CHEBI_15365

http://purl.obolibrary.org/obo/CHEBI_50838

http://purl.obolibrary.org/obo/CHEBI_63622

http://purl.obolibrary.org/obo/dinto_DB04899

http://purl.obolibrary.org/obo/dinto_DB01018

http://purl.obolibrary.org/obo/dinto_DB01340

http://purl.obolibrary.org/obo/dinto_DB00214

http://purl.obolibrary.org/obo/CHEBI_6942

http://purl.obolibrary.org/obo/dinto_DB04920

http://purl.obolibrary.org/obo/CHEBI_53766

http://purl.obolibrary.org/obo/CHEBI_7582

http://purl.obolibrary.org/obo/CHEBI_3127

http://purl.obolibrary.org/obo/CHEBI_41423

http://purl.obolibrary.org/obo/CHEBI_8774

http://purl.obolibrary.org/obo/CHEBI_3175

http://purl.obolibrary.org/obo/dinto_DB00373

http://purl.obolibrary.org/obo/CHEBI_5893

http://purl.obolibrary.org/obo/dinto_DB00270

http://purl.obolibrary.org/obo/CHEBI_7476

http://purl.obolibrary.org/obo/CHEBI_4814

http://purl.obolibrary.org/obo/CHEBI_3441

http://purl.obolibrary.org/obo/CHEBI_7822

http://purl.obolibrary.org/obo/CHEBI_39669

http://purl.obolibrary.org/obo/CHEBI_5855

http://purl.obolibrary.org/obo/dinto_DB00461

http://purl.obolibrary.org/obo/CHEBI_72014

http://purl.obolibrary.org/obo/CHEBI_7565

http://purl.obolibrary.org/obo/CHEBI_9445

http://purl.obolibrary.org/obo/dinto_DB00691

http://purl.obolibrary.org/obo/CHEBI_28502

http://purl.obolibrary.org/obo/dinto_DB00001

http://purl.obolibrary.org/obo/CHEBI_8081

http://purl.obolibrary.org/obo/CHEBI_2904

http://purl.obolibrary.org/obo/CHEBI_27690

http://purl.obolibrary.org/obo/CHEBI_9241

http://purl.obolibrary.org/obo/CHEBI_68579

http://purl.obolibrary.org/obo/dinto_DB00774

http://purl.obolibrary.org/obo/CHEBI_3347

http://purl.obolibrary.org/obo/dinto_DB01359

http://purl.obolibrary.org/obo/CHEBI_5130

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/CHEBI_48416

http://purl.obolibrary.org/obo/CHEBI_3380

http://purl.obolibrary.org/obo/CHEBI_5775

http://purl.obolibrary.org/obo/dinto_DB00939

http://purl.obolibrary.org/obo/dinto_DB00055

http://purl.obolibrary.org/obo/CHEBI_6438

http://purl.obolibrary.org/obo/dinto_DB01324

http://purl.obolibrary.org/obo/dinto_DB00232

http://purl.obolibrary.org/obo/CHEBI_3723

http://purl.obolibrary.org/obo/CHEBI_28787

http://purl.obolibrary.org/obo/CHEBI_5163

http://purl.obolibrary.org/obo/dinto_DB00310

http://purl.obolibrary.org/obo/dinto_DB00325

http://purl.obolibrary.org/obo/CHEBI_9605

http://purl.obolibrary.org/obo/CHEBI_6904

http://purl.obolibrary.org/obo/CHEBI_3013

http://purl.obolibrary.org/obo/CHEBI_3011

http://purl.obolibrary.org/obo/dinto_DB00784

http://purl.obolibrary.org/obo/CHEBI_27565

http://purl.obolibrary.org/obo/CHEBI_43755

http://purl.obolibrary.org/obo/CHEBI_55344

http://purl.obolibrary.org/obo/dinto_DB00629

http://purl.obolibrary.org/obo/dinto_DB00925

http://purl.obolibrary.org/obo/CHEBI_291902

http://purl.obolibrary.org/obo/CHEBI_63629

http://purl.obolibrary.org/obo/CHEBI_10033

http://purl.obolibrary.org/obo/CHEBI_28304

http://purl.obolibrary.org/obo/CHEBI_2379

http://purl.obolibrary.org/obo/CHEBI_4909

http://purl.obolibrary.org/obo/CHEBI_34845

http://purl.obolibrary.org/obo/dinto_DB00814

http://purl.obolibrary.org/obo/CHEBI_3082

http://purl.obolibrary.org/obo/CHEBI_9588

http://purl.obolibrary.org/obo/dinto_DB00703

http://purl.obolibrary.org/obo/dinto_DB01580

http://purl.obolibrary.org/obo/dinto_DB01113

http://purl.obolibrary.org/obo/CHEBI_9123

http://purl.obolibrary.org/obo/CHEBI_4876

http://purl.obolibrary.org/obo/CHEBI_7444

http://purl.obolibrary.org/obo/dinto_DB00465

http://purl.obolibrary.org/obo/dinto_DB00999

http://purl.obolibrary.org/obo/CHEBI_37941

http://purl.obolibrary.org/obo/CHEBI_6062

http://purl.obolibrary.org/obo/CHEBI_6061

http://purl.obolibrary.org/obo/CHEBI_6128

http://purl.obolibrary.org/obo/CHEBI_47426

http://purl.obolibrary.org/obo/CHEBI_2639

http://purl.obolibrary.org/obo/CHEBI_7575

http://purl.obolibrary.org/obo/dinto_DB00401

http://purl.obolibrary.org/obo/CHEBI_73044

http://purl.obolibrary.org/obo/CHEBI_4653

http://purl.obolibrary.org/obo/CHEBI_59173

http://purl.obolibrary.org/obo/CHEBI_46631

http://purl.obolibrary.org/obo/CHEBI_6343

http://purl.obolibrary.org/obo/CHEBI_8364

http://purl.obolibrary.org/obo/CHEBI_4784

http://purl.obolibrary.org/obo/CHEBI_4708

http://purl.obolibrary.org/obo/CHEBI_101085

http://purl.obolibrary.org/obo/CHEBI_47381

http://purl.obolibrary.org/obo/CHEBI_2788

http://purl.obolibrary.org/obo/dinto_DB03904

http://purl.obolibrary.org/obo/dinto_DB00622

http://purl.obolibrary.org/obo/CHEBI_2668

http://purl.obolibrary.org/obo/CHEBI_5118
modulates

http://purl.obolibrary.org/obo/dinto_2806

http://purl.obolibrary.org/obo/dinto_1874

http://purl.obolibrary.org/obo/dinto_0168
prefixIRI

obo2:CHEBI_50861
prefLabel

treprostinil
SMILES

[H][C@]12C[C@@H](O)[C@H](CC[C@@H](O)CCCCC)[C@@]1([H])CC1=C(C2)C(OCC(O)=O)=CC=C1

[H][C@]12C[C@@H](O)[C@H](CC[C@@H](O)CCCCC)[C@@]1([H])Cc1cccc(OCC(O)=O)c1C2
Synonym

treprostinil

({(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta[b]naphthalen-5-yl}oxy)acetic acid

treprostinilo

C23H34O5

2-{[(1R,2R,3aS,9aS)-2-hydroxy-1-[(3S)-3-hydroxyoctyl]-1H,2H,3H,3aH,4H,9H,9aH-cyclopenta[b]naphthalen-5-yl]oxy}acetic acid

treprostinilum
xref

CASRN:81846-19-7

DrugBank:DB00374

ChEMBL:799470

Drugs.com:http://www.drugs.com/cdi/treprostinil-inhalation-solution.html

Wikipedia:http://en.wikipedia.org/wiki/Treprostinil

PharmGKB:PA164768801

RxList:http://www.rxlist.com/cgi/generic/remodulin.htm

Drugs Product Database (DPD):2246552

KEGG DRUG:D06213

ChEBI:50861

National Drug Code Directory:66302-206-01
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Delete Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_50861 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50861 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50861 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50861 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50861 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50861 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_50861 NIFSTD SAME_URI
http://purl.bioontology.org/ontology/NDFRT/N0000148769 NDFRT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61983 NCIT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00025414 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/MESH/C427248 MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C427248 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/443570007 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/RXNORM/343048 RXNORM LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_50861 NIFSTD LOOM
http://purl.bioontology.org/ontology/ATC/B01AC21 ATC LOOM
http://purl.bioontology.org/ontology/VANDF/4021349 VANDF LOOM
http://purl.obolibrary.org/obo/NCIT_C61983 BERO LOOM
https://go.drugbank.com/drugs/DB00374 MDM LOOM
http://www.drugbank.ca/drugs/DB00374 FTC LOOM