The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Preferred Name

fexofenadine
Synonyms

Terfenadine acid metabolite

Fexofenadine

Terfenadine-COOH

2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid

4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid

Carboxyterfenadine

Terfenadine carboxylate

C32H39NO4

ID

http://purl.obolibrary.org/obo/CHEBI_5050

AHFScode

04:08.00

ATCCode

R06AX26

binds

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1824

http://purl.obolibrary.org/obo/dinto_1071

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_1322

blocks

http://purl.obolibrary.org/obo/dinto_1071

CASRN

83799-24-0

DBBrand

allegra-d 24 hour

allegra

allegra-d 12 hour

DBname

fexofenadine

DBSynonym

terfenadine carboxylate

terfenadine-cooh

fexofenadine hydrochloride

carboxyterfenadine

fexofendine

terfenadine acid metabolite

Definition

A piperidine-based anti-histamine compound.

has effect

http://purl.obolibrary.org/obo/OAE_0000388

http://purl.obolibrary.org/obo/OAE_0000453

http://purl.obolibrary.org/obo/OAE_0001373

http://purl.obolibrary.org/obo/OAE_0000081

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000391

http://purl.obolibrary.org/obo/OAE_0000659

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0000567

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0000021

http://purl.obolibrary.org/obo/OAE_0000365

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000340

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000375

http://purl.obolibrary.org/obo/OAE_0000517

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0002206

http://purl.obolibrary.org/obo/OAE_0000473

http://purl.obolibrary.org/obo/OAE_0000414

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0001403

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0000505

http://purl.obolibrary.org/obo/OAE_0000022

http://purl.obolibrary.org/obo/OAE_0000336

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000466

http://purl.obolibrary.org/obo/OAE_0000358

http://purl.obolibrary.org/obo/OAE_0001309

http://purl.obolibrary.org/obo/OAE_0000402

has pharmacological target

http://purl.obolibrary.org/obo/dinto_1071

has role

http://purl.obolibrary.org/obo/CHEBI_37955

http://purl.obolibrary.org/obo/CHEBI_50857

InChI

InChI=1S/C32H39NO4/c1-31(2,30(35)36)25-17-15-24(16-18-25)29(34)14-9-21-33-22-19-28(20-23-33)32(37,26-10-5-3-6-11-26)27-12-7-4-8-13-27/h3-8,10-13,15-18,28-29,34,37H,9,14,19-23H2,1-2H3,(H,35,36)

InChIKey

InChIKey=RWTNPBWLLIMQHL-UHFFFAOYSA-N

inhibits

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_1440

is substrate of

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1322

is transported by

http://purl.obolibrary.org/obo/dinto_1987

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1322

label

fexofenadine

may interact with

http://purl.obolibrary.org/obo/dinto_DB00209

http://purl.obolibrary.org/obo/dinto_DB00427

http://purl.obolibrary.org/obo/CHEBI_3720

http://purl.obolibrary.org/obo/CHEBI_27796

http://purl.obolibrary.org/obo/dinto_DB00382

modulates

http://purl.obolibrary.org/obo/dinto_1071

prefixIRI

obo2:CHEBI_5050

prefLabel

fexofenadine

related with

http://purl.obolibrary.org/obo/dinto_2019

http://purl.obolibrary.org/obo/dinto_1824

SMILES

CC(C)(C(O)=O)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1

CC(C)(C(O)=O)c1ccc(cc1)C(O)CCCN1CCC(CC1)C(O)(c1ccccc1)c1ccccc1

Synonym

Terfenadine acid metabolite

Fexofenadine

Terfenadine-COOH

2-(4-{1-hydroxy-4-[4-(hydroxydiphenylmethyl)piperidin-1-yl]butyl}phenyl)-2-methylpropanoic acid

4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acid

Carboxyterfenadine

Terfenadine carboxylate

C32H39NO4

xref

CASRN:83799-24-0

PubChem Substance:46504676

PharmGKB:PA449621

Drugs.com:http://www.drugs.com/cdi/fexofenadine.html

Wikipedia:http://en.wikipedia.org/wiki/Fexofenadine

Wikipedia:Fexofenadine

Beilstein:6832242

Drugs Product Database (DPD):2242819

ChEBI:5050

PubChem Compound:3348

National Drug Code Directory:0339-6461-11

ChEMBL:181683

RxList:http://www.rxlist.com/cgi/generic/fexofen.htm

ChemSpider:3231

DrugBank:DB00950

BindingDB:22874

Patent:DE3007498

KEGG COMPOUND:C06999

Patent:US4254129

subClassOf

http://purl.obolibrary.org/obo/dinto_000055

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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_5050 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_5050 DRON LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C093230 RH-MESH LOOM
http://purl.bioontology.org/ontology/RCD/c8p.. RCD LOOM
http://doe-generated-ontology.com/OntoAD#C0296800 ONTOAD LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/372522002 SNOMEDCT LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61764 NCIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU036232 LOINC LOOM
http://stirdf.jst.go.jp/id/200907076547833810 IOBC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#27786 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4024052 VANDF LOOM
http://purl.bioontology.org/ontology/LNC/LP101033-1 LOINC LOOM
http://purl.bioontology.org/ontology/MESH/C093230 MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_5050 NIFSTD LOOM
http://www.phoc.org.cn/pmo/class/PMO_00026710 PMAPP-PMO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0296800 OCHV LOOM
http://purl.bioontology.org/ontology/NDDF/006063 NDDF LOOM
http://purl.obolibrary.org/obo/NCIT_C61764 BERO LOOM
https://github.com/sap218/coid/blob/master/coid.owl#COID_00848 COID LOOM
http://www.drugbank.ca/drugs/DB00950 FTC LOOM
http://purl.jp/bio/4/id/200906033703709674 IOBC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022057 NDFRT LOOM
http://purl.bioontology.org/ontology/ATC/R06AX26 ATC LOOM
https://go.drugbank.com/drugs/DB00950 MDM LOOM
http://purl.bioontology.org/ontology/RXNORM/87636 RXNORM LOOM