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The Drug-Drug Interactions Ontology
| Preferred Name | enalapril | |
| Synonyms |
Enalapril (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline ENALAPRIL enalaprila enalaprilum analapril C20H28N2O5 enalapril |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4784 |
|
| AHFScode |
24:32.04
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|
| altId |
CHEBI:116847
|
|
| ATCCode |
C09AA02
|
|
| binds |
http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_1440 http://purl.obolibrary.org/obo/dinto_0520 http://purl.obolibrary.org/obo/dinto_2130 |
|
| CASRN |
75847-73-3
|
|
| DBBrand |
vasotec kinfil gadopril vasotec iv bonuten
|
|
| DBname |
enalapril
|
|
| DBSynonym |
enalaprilat enalaprilum [inn-latin] enalapril maleate enalaprila [inn-spanish]
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|
| Definition |
A dicarboxylic acid monoester that is ethyl 4-phenylbutanoate in which a hydrogen alpha to the carboxy group is substituted by the amino group of L-alanyl-L-proline (S-configuration).
|
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35674 |
|
| InChI |
InChI=1S/C20H28N2O5/c1-3-27-20(26)16(12-11-15-8-5-4-6-9-15)21-14(2)18(23)22-13-7-10-17(22)19(24)25/h4-6,8-9,14,16-17,21H,3,7,10-13H2,1-2H3,(H,24,25)/t14-,16-,17-/m0/s1
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|
| InChIKey |
InChIKey=GBXSMTUPTTWBMN-XIRDDKMYSA-N
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|
| inhibits |
http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_1440 |
|
| is metabolised by | ||
| is substrate of |
http://purl.obolibrary.org/obo/dinto_0901 |
|
| is transported by | ||
| label |
enalapril
|
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00384 http://purl.obolibrary.org/obo/CHEBI_50838 http://purl.obolibrary.org/obo/CHEBI_9241 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/CHEBI_50861 http://purl.obolibrary.org/obo/dinto_DB00684 http://purl.obolibrary.org/obo/CHEBI_63629 http://purl.obolibrary.org/obo/dinto_DB00046 http://purl.obolibrary.org/obo/CHEBI_2639 http://purl.obolibrary.org/obo/CHEBI_68564 http://purl.obolibrary.org/obo/CHEBI_68845 |
|
| prefixIRI |
obo2:CHEBI_4784
|
|
| prefLabel |
enalapril
|
|
| SMILES |
CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@@H](C)C(=O)N1CCC[C@H]1C(O)=O
|
|
| Synonym |
Enalapril (2S)-1-[(2S)-2-{[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino}propanoyl]pyrrolidine-2-carboxylic acid (S)-1-(N-(1-(ethoxycarbonyl)-3-phenylpropyl)-L-alanyl)-L-proline 1-(N-((S)-1-carboxy-3-phenylpropyl)-L-alanyl)-L-proline 1'-ethyl ester (S)-1-{(S)-2-[1-((S)-Ethoxycarbonyl)-3-phenyl-propylamino]-propionyl}-pyrrolidine-2-carboxylic acid N-[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl-L-proline ENALAPRIL enalaprila enalaprilum analapril C20H28N2O5 enalapril
|
|
| xref |
National Drug Code Directory:0378-1051-01 ChEBI:4784 PDRhealth:http://www.pdrhealth.com/drugs/rx/rx-mono.aspx?contentFileNam Wikipedia:http://en.wikipedia.org/wiki/Enalapril KEGG DRUG:D07892 KEGG COMPOUND:C06977 HMDB:HMDB14722 PDB:EAL Wikipedia:Enalapril MetaCyc:CPD0-2065 CiteXplore:23413003 Beilstein:3657467 Drugs.com:http://www.drugs.com/enalapril.html CASRN:75847-73-3 Drugs Product Database (DPD):2019906 Patent:EP12401 Patent:US4374829 RxList:http://www.rxlist.com/cgi/generic/enalap.htm CiteXplore:23030053 DrugBank:DB00584 ChEMBL:10669559 PharmGKB:PA449456
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| subClassOf |
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