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The Drug-Drug Interactions Ontology
| Preferred Name | dyphylline | |
| Synonyms |
(1,2-dihydroxy-3-propyl)thiophyllin C10H14N4O4 7-(2,3-dihydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 7-(beta,gamma-dihydroxypropyl)theophylline 1,3-dimethyl-7-(2,3-dihydroxypropyl)xanthine diprophylline 7-(2,3-dihydroxypropyl)-1,3-dimethylxanthine Dyphylline (+-)-7-(2,3-dihydroxypropyl)theophylline diprophyllinum (+-)-dyphylline Dihydroxypropyl theopylin 7-(2,3-dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione diprofilina (+-)-diprophylline Diprophylline 7-(2,3-dihydroxypropyl)theophylline 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4728 |
|
| altId |
CHEBI:681819
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|
| ATCCode |
R03DA01
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|
| binds |
http://purl.obolibrary.org/obo/dinto_3498 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_3125 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_3980 http://purl.obolibrary.org/obo/dinto_2945 |
|
| blocks | ||
| CASRN |
479-18-5
|
|
| DBBrand |
asthmolysin glyphyllin neufil coronal neophylline astrophyllin silbephylline hidroxiteofillina neutraphylline afi-phyllin dyflex coronarin corphyllin synthophylline thefylan glyfyllin glyphylline neutroxantina neostenovasan purifilin circain propyphyllin neotilina neophyl droxine liactemin hiphyllin neutrafil silbephyllin iphyllin cor-theophylline hyphylline tefilan theal neo-vasophylline protheophylline solufyllin neophyllin teofen aristophyllin neutraphyllin solufilin soluphyllin neutrafillina
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|
| DBname |
dyphylline
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|
| DBSynonym |
dt diprophylline diprofilline dihydroxypropyl theophylline diprophyllin diprofillin dipropylline dihydroxypropyl theopylin
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|
| Definition |
An oxopurine that is theophylline bearing a 2,3-dihydroxypropyl group at the 7 position. It has broncho- and vasodilator properties, and is used in the treatment of asthma, cardiac dyspnea, and bronchitis. It is also an ingredient in preparations that have been promoted for coughs.
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|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0001003 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000306 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_3607 http://purl.obolibrary.org/obo/dinto_3498 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_3125 http://purl.obolibrary.org/obo/dinto_0074 http://purl.obolibrary.org/obo/dinto_3980 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_51371 http://purl.obolibrary.org/obo/CHEBI_35620 |
|
| InChI |
InChI=1S/C10H14N4O4/c1-12-8-7(9(17)13(2)10(12)18)14(5-11-8)3-6(16)4-15/h5-6,15-16H,3-4H2,1-2H3
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|
| InChIKey |
InChIKey=KSCFJBIXMNOVSH-UHFFFAOYSA-N
|
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_3498 http://purl.obolibrary.org/obo/dinto_4063 http://purl.obolibrary.org/obo/dinto_3125 http://purl.obolibrary.org/obo/dinto_0074 |
|
| label |
dyphylline
|
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_8214 http://purl.obolibrary.org/obo/CHEBI_8107 http://purl.obolibrary.org/obo/dinto_DB00822 http://purl.obolibrary.org/obo/dinto_DB00794 http://purl.obolibrary.org/obo/CHEBI_16335 http://purl.obolibrary.org/obo/CHEBI_8499 http://purl.obolibrary.org/obo/dinto_DB00806 http://purl.obolibrary.org/obo/dinto_DB00011 http://purl.obolibrary.org/obo/dinto_DB00857 http://purl.obolibrary.org/obo/dinto_DB00231 http://purl.obolibrary.org/obo/CHEBI_8069 http://purl.obolibrary.org/obo/CHEBI_2453 http://purl.obolibrary.org/obo/CHEBI_3699 http://purl.obolibrary.org/obo/dinto_DB00373 http://purl.obolibrary.org/obo/dinto_DB00034 http://purl.obolibrary.org/obo/dinto_DB00105 http://purl.obolibrary.org/obo/dinto_DB01558 http://purl.obolibrary.org/obo/dinto_DB00365 http://purl.obolibrary.org/obo/CHEBI_6916 http://purl.obolibrary.org/obo/dinto_DB01356 http://purl.obolibrary.org/obo/CHEBI_100241 http://purl.obolibrary.org/obo/CHEBI_100246 http://purl.obolibrary.org/obo/CHEBI_5138 http://purl.obolibrary.org/obo/CHEBI_3387 http://purl.obolibrary.org/obo/CHEBI_8466 http://purl.obolibrary.org/obo/CHEBI_3732 http://purl.obolibrary.org/obo/dinto_DB00022 http://purl.obolibrary.org/obo/CHEBI_9588 http://purl.obolibrary.org/obo/dinto_DB00199 http://purl.obolibrary.org/obo/CHEBI_7444 http://purl.obolibrary.org/obo/dinto_DB00977 http://purl.obolibrary.org/obo/dinto_DB00008 http://purl.obolibrary.org/obo/dinto_DB01320 |
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| modulates | ||
| prefixIRI |
obo2:CHEBI_4728
|
|
| prefLabel |
dyphylline
|
|
| SMILES |
Cn1c2ncn(CC(O)CO)c2c(=O)n(C)c1=O CN1C2=C(N(CC(O)CO)C=N2)C(=O)N(C)C1=O
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| Synonym |
(1,2-dihydroxy-3-propyl)thiophyllin C10H14N4O4 7-(2,3-dihydroxypropyl)-1,3-dimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-dione 7-(beta,gamma-dihydroxypropyl)theophylline 1,3-dimethyl-7-(2,3-dihydroxypropyl)xanthine diprophylline 7-(2,3-dihydroxypropyl)-1,3-dimethylxanthine Dyphylline (+-)-7-(2,3-dihydroxypropyl)theophylline diprophyllinum (+-)-dyphylline Dihydroxypropyl theopylin 7-(2,3-dihydroxypropyl)-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione diprofilina (+-)-diprophylline Diprophylline 7-(2,3-dihydroxypropyl)theophylline 7-(2,3-dihydroxypropyl)-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione
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|
| xref |
CASRN:479-18-5 Drugs.com:http://www.drugs.com/cdi/dyphylline.html NIST Chemistry WebBook:479-18-5 Wikipedia:Dyphylline ChEBI:4728 RxList:http://www.rxlist.com/cgi/generic2/dyphylline.htm National Drug Code Directory:0037-0521-92 PubChem Substance:46504443 Reaxys:284563 Drugs Product Database (DPD):26751 PubChem Compound:3182 KEGG COMPOUND:C07819 DrugBank:DB00651 ChemSpider:3070 Beilstein:284563 KEGG DRUG:D00691 PharmGKB:PA164748027 Patent:US2575344
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| subClassOf |
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