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The Drug-Drug Interactions Ontology
| Preferred Name | dobutamine | |
| Synonyms |
DOBUTAMINE 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol DL-dobutamine 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine dobutamine C18H23NO3 dobutaminum 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol racemic-dobutamine Dobutamine rac-dobutamine dobutamina |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4670 |
|
| activates | ||
| AHFScode |
12:12.08.08
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|
| altId |
CHEBI:554519 CHEBI:184505
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|
| ATCCode |
C01CA07
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|
| binds |
http://purl.obolibrary.org/obo/dinto_2907 |
|
| CASRN |
34368-04-2
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|
| DBBrand |
dobutamine [usan:ban:inn] dobutamine hcl dobutaminum [inn-latin] racemic-dobutamine dobutamina [inn-spanish] dobutamine hcl in dextrose 5% dobutamine hydrochloride inotrex dobutamine [usan] dobutrex
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|
| DBname |
dobutamine
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|
| Definition |
4-(3-Aminobutyl)phenol in which one of the hydrogens attached to the nitrogen is substituted by a 2-(3,4-dihydroxyphenyl)ethyl group. A beta1-adrenergic receptor agonist that has cardiac stimulant action without evoking vasoconstriction or tachycardia, it is used as the hydrochloride to increase the contractility of the heart in the management of acute heart failure.
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|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000406 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001740 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0002122 http://purl.obolibrary.org/obo/OAE_0001742 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35524 |
|
| InChI |
InChI=1S/C18H23NO3/c1-13(2-3-14-4-7-16(20)8-5-14)19-11-10-15-6-9-17(21)18(22)12-15/h4-9,12-13,19-22H,2-3,10-11H2,1H3
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|
| InChIKey |
InChIKey=JRWZLRBJNMZMFE-UHFFFAOYSA-N
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|
| is metabolised by | ||
| is substrate of | ||
| label |
dobutamine
|
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_28487 http://purl.obolibrary.org/obo/dinto_DB01142 http://purl.obolibrary.org/obo/dinto_DB00540 http://purl.obolibrary.org/obo/CHEBI_47499 http://purl.obolibrary.org/obo/CHEBI_47780 http://purl.obolibrary.org/obo/dinto_DB00780 http://purl.obolibrary.org/obo/CHEBI_4798 http://purl.obolibrary.org/obo/dinto_DB01247 http://purl.obolibrary.org/obo/CHEBI_63607 http://purl.obolibrary.org/obo/dinto_DB01171 http://purl.obolibrary.org/obo/CHEBI_5557 http://purl.obolibrary.org/obo/CHEBI_61058 http://purl.obolibrary.org/obo/CHEBI_63620 http://purl.obolibrary.org/obo/CHEBI_6933 http://purl.obolibrary.org/obo/CHEBI_47781 |
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_4670
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|
| prefLabel |
dobutamine
|
|
| SMILES |
CC(CCC1=CC=C(O)C=C1)NCCC1=CC(O)=C(O)C=C1 CC(CCc1ccc(O)cc1)NCCc1ccc(O)c(O)c1
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|
| Synonym |
DOBUTAMINE 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol DL-dobutamine 3,4-dihydroxy-N-[3-(4-hydroxyphenyl)-1-methylpropyl]-beta-phenylethylamine dobutamine C18H23NO3 dobutaminum 4-(2-{[4-(4-hydroxyphenyl)butan-2-yl]amino}ethyl)benzene-1,2-diol (+-)-4-(2-((3-(p-hydroxyphenyl)-1-methylpropyl)amino)ethyl)pyrocatechol racemic-dobutamine Dobutamine rac-dobutamine dobutamina
|
|
| xref |
ChemSpider:33786 RxList:http://www.rxlist.com/cgi/generic3/dobutamine.htm Patent:DE2317710 National Drug Code Directory:55390-560-90 Guide To Pharmacology:535 ChEBI:4670 CiteXplore:11950781 DrugBank:DB00841 CASRN:34368-04-2 Beilstein:2946389 Drugs Product Database (DPD):2242010 BindingDB:50028971 IUPHAR:535 Drugs.com:http://www.drugs.com/cdi/dobutamine.html PharmGKB:PA449381 Wikipedia:http://en.wikipedia.org/wiki/Dobutamine Wikipedia:Dobutamine CiteXplore:22537238 KEGG DRUG:D03879 PubChem Compound:36811 CiteXplore:11280019 CiteXplore:18323735 PubChem Substance:46505241 Patent:US3987200 Reaxys:2946389 KEGG COMPOUND:C06967
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| subClassOf |
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