loading...| Preferred Name |
dipivefrin |
|
| Synonyms |
Dipivefrine 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate (+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate Dipivefrin dipivefrina dipivefrine 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate) 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol dipivefrinum C19H29NO5 dipivalyl epinephrine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4646 |
|
| activates |
http://purl.obolibrary.org/obo/dinto_0234 |
|
| AHFScode |
52:24.00 |
|
| ATCCode |
S01EA02 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_3568 http://purl.obolibrary.org/obo/dinto_0234 |
|
| CASRN |
52365-63-6 |
|
| DBBrand |
akpro dipivefrin hcl ophtho-dipivefrin propine c cap b.i.d. propine dipivefrine dipivefrina [inn-spanish] dipivefrin [usan] dipivefrinum [inn-latin] |
|
| DBname |
dipivefrin |
|
| Definition |
The dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension. |
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000660 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0000837 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000470 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_3568 http://purl.obolibrary.org/obo/dinto_0234 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_39456 http://purl.obolibrary.org/obo/CHEBI_35524 http://purl.obolibrary.org/obo/CHEBI_37886 |
|
| InChI |
InChI=1S/C19H29NO5/c1-18(2,3)16(22)24-14-9-8-12(13(21)11-20-7)10-15(14)25-17(23)19(4,5)6/h8-10,13,20-21H,11H2,1-7H3 |
|
| InChIKey |
InChIKey=OCUJLLGVOUDECM-UHFFFAOYSA-N |
|
| label |
dipivefrin |
|
| may interact with | ||
| modulates |
http://purl.obolibrary.org/obo/dinto_0234 |
|
| prefixIRI |
obo2:CHEBI_4646 |
|
| prefLabel |
dipivefrin |
|
| related with | ||
| SMILES |
CNCC(O)C1=CC(OC(=O)C(C)(C)C)=C(OC(=O)C(C)(C)C)C=C1 CNCC(O)c1ccc(OC(=O)C(C)(C)C)c(OC(=O)C(C)(C)C)c1 |
|
| Synonym |
Dipivefrine 2-[(2,2-dimethylpropanoyl)oxy]-5-[1-hydroxy-2-(methylamino)ethyl]phenyl 2,2-dimethylpropanoate 4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate (+-)-4-[1-hydroxy-2-(methylamino)ethyl]-o-phenylene divavalate Dipivefrin dipivefrina dipivefrine 4-[1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diyl bis(2,2-dimethylpropanoate) 1-(3',4'-dipivaloyloxyphenyl)-2-methylamino-1-ethanol dipivefrinum C19H29NO5 dipivalyl epinephrine |
|
| xref |
Beilstein:2165183 Patent:DE2152058 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/pro1356.shtml KEGG DRUG:D02349 Drugs.com:http://www.drugs.com/cdi/dipivefrin.html Patent:DE2343657 DrugBank:DB00449 KEGG COMPOUND:C06963 PharmGKB:PA449364 RxList:http://www.rxlist.com/cgi/generic2/dipivefrin.htm National Drug Code Directory:0023-9208-10 PubChem Compound:3105 PubChem Substance:46504716 Drugs Product Database (DPD):2242232 ChemSpider:2994 Wikipedia:Dipivefrin ChEMBL:775213 Patent:US4085270 Patent:US3809714 ChEBI:4646 CASRN:52365-63-6 Wikipedia:http://en.wikipedia.org/wiki/Dipivefrin |
|
| subClassOf |