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The Drug-Drug Interactions Ontology
| Preferred Name | diphenhydramine | |
| Synonyms |
diphenhydraminum O-benzhydryldimethylaminoethanol difenhidramina C17H21NO 2-(benzhydryloxy)-N,N-dimethylethylamine beta-dimethylaminoethanol diphenylmethyl ether 2-(diphenylmethoxy)-N,N-dimethylethanamine diphenhydramine beta-dimethylaminoethyl benzhydryl ether 2-diphenylmethoxy-N,N-demthylethanamine [2-(diphenylmethoxy)ethyl]dimethylamine alpha-(2-dimethylaminoethoxy)diphenylmethane N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_4636 |
|
| AHFScode |
04:04.04
|
|
| ATCCode |
R06AA02 D04AA33 D04AA32
|
|
| binds |
http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1970 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_2789 http://purl.obolibrary.org/obo/dinto_1071 http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_1959 |
|
| blocks | ||
| CASRN |
58-73-1
|
|
| DBBrand |
vicks formula 44 nytol quickcaps benodin twilite caplets hyadrine benapon restamin diphen cough diphen diabylen nausen debendrin bena dibendrin nytol quickgels antomin desentol dibenil syntedril dryistan automin dylamon syntodril difedryl beldin benylin probedryl ambodryl sleep-eze d siladryl diphantine compoz benadryl dermistina allergina dermodrin allergical banophen allergan b dimedryl diphenhist hyrexin diabenyl histaxin silphen aleryl dimedrol mephadryl alledryl dibondrin allermax caplets novamina amidryl benylan ben-allergin benadrin rigidil unisom sleepgels maximum strength drylistan allergeval genahist allergival dihidral benachlor dormarex 2 betramin etanautine belix hydramine bagodryl nervine nighttime sleep-aid allerdryl vena ibiodral benodine baramine allergin dabylen medidryl
|
|
| DBname |
diphenhydramine
|
|
| DBSalt |
diphenhydramine hcl diphenhydramine salicylate
|
|
| DBSynonym |
2-diphenylmethoxy-n,n-demthylethanamine o-benzhydryldimethylaminoethanol ?-dimethylaminoethyl benzhydryl ether diphenylhydramine
|
|
| Definition |
The benzhydryl ether of 2-(dimethylamino)ethanol.
|
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0001509 http://purl.obolibrary.org/obo/OAE_0001489 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001105 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000034 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0000306 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000362 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_37955 http://purl.obolibrary.org/obo/CHEBI_66956 http://purl.obolibrary.org/obo/CHEBI_48876 http://purl.obolibrary.org/obo/CHEBI_36333 http://purl.obolibrary.org/obo/CHEBI_50919 http://purl.obolibrary.org/obo/CHEBI_35717 http://purl.obolibrary.org/obo/CHEBI_59683 http://purl.obolibrary.org/obo/CHEBI_51177 |
|
| InChI |
InChI=1S/C17H21NO/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16/h3-12,17H,13-14H2,1-2H3
|
|
| InChIKey |
InChIKey=ZZVUWRFHKOJYTH-UHFFFAOYSA-N
|
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_1979 http://purl.obolibrary.org/obo/dinto_1970 |
|
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_1959 |
|
| is substrate of |
http://purl.obolibrary.org/obo/dinto_2651 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 http://purl.obolibrary.org/obo/dinto_0291 http://purl.obolibrary.org/obo/dinto_1959 |
|
| label |
diphenhydramine
|
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_32250 http://purl.obolibrary.org/obo/CHEBI_127342 http://purl.obolibrary.org/obo/CHEBI_41774 http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00209 http://purl.obolibrary.org/obo/CHEBI_8874 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/CHEBI_6780 http://purl.obolibrary.org/obo/CHEBI_9566 http://purl.obolibrary.org/obo/dinto_DB00427 http://purl.obolibrary.org/obo/CHEBI_27796 |
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_4636
|
|
| prefLabel |
diphenhydramine
|
|
| SMILES |
CN(C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1 CN(C)CCOC(c1ccccc1)c1ccccc1
|
|
| Synonym |
diphenhydraminum O-benzhydryldimethylaminoethanol difenhidramina C17H21NO 2-(benzhydryloxy)-N,N-dimethylethylamine beta-dimethylaminoethanol diphenylmethyl ether 2-(diphenylmethoxy)-N,N-dimethylethanamine diphenhydramine beta-dimethylaminoethyl benzhydryl ether 2-diphenylmethoxy-N,N-demthylethanamine [2-(diphenylmethoxy)ethyl]dimethylamine alpha-(2-dimethylaminoethoxy)diphenylmethane N-(2-(diphenylmethoxy)ethyl)-N,N-dimethylamine
|
|
| xref |
KEGG DRUG:D00300 DrugBank:DB01075 IUPHAR:1224 Patent:US2421714 CASRN:58-73-1 Drugs Product Database (DPD):2244203 National Drug Code Directory:0121-0489-05 Guide To Pharmacology:1224 ChemSpider:2989 Patent:US2427878 PDB:2PM NIST Chemistry WebBook:58-73-1 PharmGKB:PA449349 ChEMBL:127629 Drugs.com:http://www.drugs.com/cdi/diphenhydramine.html ChEBI:4636 RxList:http://www.rxlist.com/cgi/generic/dihydram.htm PubChem Compound:3100 Beilstein:1914136 Wikipedia:http://en.wikipedia.org/wiki/Diphenhydramine PubChem Substance:46505484
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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