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The Drug-Drug Interactions Ontology
| Preferred Name | dimenhydrinate | |
| Synonyms |
C24H28ClN5O3 Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline dimenhydrinate O-benzhydryldimethylaminoethanol 8-chlorotheophyllinate dimenhydrinatum 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) beta-dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine 8-chloro-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide; [2-(diphenylmethoxy)ethyl]dimethylazanium N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate diphenhydramine theoclate (O-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate dimenhidrinato 2-(diphenylmethoxy)-N,N-dimethylethanaminium 8-chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide diphenhydramine 8-chlorotheophyllinate diphenhydramine 8-chlorotheophylline |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_4604 |
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| AHFScode |
56:22.08
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| ATCCode |
R06AA02
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| binds | ||
| blocks | ||
| CASRN |
523-87-5
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| DBBrand |
anautine eldodram dromyl aviomarin dimenest diamarin andramine novamine dramarin dramalen dimentabs dramamin dimate xamamina vomex a reise-engletten neo-navigan chloranautine gravol teodramin travelmin dramilin dramyl antemin gravinol permital troversin supremal travelin amosyt menhydrinate hydrinate
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| DBname |
dimenhydrinate
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| DBSynonym |
diphenhydrinate
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| Definition |
The diphenhydramine salt of 8-chlorotheophylline. Its effects are similar to those of diphenhydramine, but it is less potent. It was thought that by combining the antiemetic effects of diphenhydramine with the mild stimulant effects of 8-chlorotheophyline, the extreme drowsiness induced by the former would be mitigated. However, the sedation caused by diphenhydramine is considerably stronger than the stimulation caused by 8-chlorotheophylline. Dimenhydrinate is used mainly as an antiemetic in the prevention and treatment of motion sickness.
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C17H21NO.C7H7ClN4O2/c1-18(2)13-14-19-17(15-9-5-3-6-10-15)16-11-7-4-8-12-16;1-11-4-3(9-6(8)10-4)5(13)12(2)7(11)14/h3-12,17H,13-14H2,1-2H3;1-2H3,(H,9,10,13)
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| InChIKey |
InChIKey=DKHVTDUUNTVKOW-UHFFFAOYSA-N
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| label |
dimenhydrinate
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| may interact with |
http://purl.obolibrary.org/obo/CHEBI_42944 http://purl.obolibrary.org/obo/dinto_DB00209 http://purl.obolibrary.org/obo/CHEBI_8874 http://purl.obolibrary.org/obo/CHEBI_53289 http://purl.obolibrary.org/obo/dinto_DB00427 |
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| modulates | ||
| prefixIRI |
obo2:CHEBI_4604
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| prefLabel |
dimenhydrinate
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| SMILES |
Cn1c2nc(Cl)[n-]c2c(=O)n(C)c1=O.C[NH+](C)CCOC(c1ccccc1)c1ccccc1 CN1C2=C([N-]C(Cl)=N2)C(=O)N(C)C1=O.C[NH+](C)CCOC(C1=CC=CC=C1)C1=CC=CC=C1
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| Synonym |
C24H28ClN5O3 Benzhydryl-beta-dimethylaminoethylether 8-chlorotheophylline dimenhydrinate O-benzhydryldimethylaminoethanol 8-chlorotheophyllinate dimenhydrinatum 8-chloro-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) beta-dimethylaminoethyl benzhydryl ether 1,3-dimethyl-8-chloroxanthine 8-chloro-1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-7-ide; [2-(diphenylmethoxy)ethyl]dimethylazanium N,N-dimethyl-2-diphenylmethoxyethylamine 8-chlorotheophyllinate diphenhydramine theoclate (O-benzhydryl(dimethylamino)ethanol) 8-chlorotheophyllinate dimenhidrinato 2-(diphenylmethoxy)-N,N-dimethylethanaminium 8-chloro-1,3-dimethyl-2,6-dioxo-1,2,3,6-tetrahydropurin-7-ide diphenhydramine 8-chlorotheophyllinate diphenhydramine 8-chlorotheophylline
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| xref |
Wikipedia:http://en.wikipedia.org/wiki/Dimenhydrinate ChEBI:4604 PubChem Compound:441281 CASRN:523-87-5 Drugs Product Database (DPD):2241532 PharmGKB:PA449338 National Drug Code Directory:0409-0468-05 Patent:US2534813 ChemSpider:390044 PubChem Substance:46504881 Patent:US2499058 KEGG DRUG:D00520 DrugBank:DB00985 Drugs.com:http://www.drugs.com/cdi/dimenhydrinate.html
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