| Synonyms |
diazoxidum
7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine-1,1-dione
Diazossido
Diazoxide
diazoxide
7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide
diazoxido
C8H7ClN2O2S
Eudemine
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| Definition |
A benzothiadiazine that is the S,S-dioxide of 2H-1,2,4-benzothiadiazine which is substituted at position 3 by a methyl group and at position 7 by chlorine. A peripheral vasodilator, it increases the concentration of glucose in the plasma and inhibits the secretion of insulin by the beta- cells of the pancreas. It is used orally in the management of intractable hypoglycaemia and intravenously in the management of hypertensive emergencies.
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| InChI |
InChI=1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
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| Synonym |
diazoxidum 7-chloro-3-methyl-4H-1$l^{6},2,4-benzothiadiazine-1,1-dione Diazossido Diazoxide diazoxide 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide diazoxido C8H7ClN2O2S Eudemine
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| xref |
Wikipedia:http://en.wikipedia.org/wiki/Diazoxide CiteXplore:15319354 PubChem Compound:3019 CiteXplore:20828743 CiteXplore:20950601 ChEBI:4495 PubChem Substance:46508027 Beilstein:523907 CiteXplore:16777075 CiteXplore:16740260 ChemSpider:2911 CiteXplore:18191077 CiteXplore:21693179 National Drug Code Directory:0575-6000-01 Drugs Product Database (DPD):503347 Guide To Pharmacology:2409 Patent:DE723278 CASRN:364-98-7 ChEMBL:464859 DrugBank:DB01119 CiteXplore:22047130 CiteXplore:21538163 Reaxys:523907 KEGG COMPOUND:C06949 KEGG DRUG:D00294 Patent:US2986573 CiteXplore:12039709 Drugs.com:http://www.drugs.com/cdi/diazoxide-suspension.html Patent:US3345365 IUPHAR:2409 PharmGKB:PA449285 Wikipedia:Diazoxide CiteXplore:11014217
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