The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
Jump to:
loading...
Preferred Name

(S)-fenfluramine
Synonyms

dexfenfluramine

ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine

(S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

(S)-fenfluramine

dextrofenfluramine

(+)-fenfluramine

(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

dexfenfluramina

C12H16F3N

d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine

dexfenfluraminum
ID

http://purl.obolibrary.org/obo/CHEBI_439329
activates

http://purl.obolibrary.org/obo/dinto_0510
ATCCode

A08AA04
CASRN

3239-44-9
DBBrand

adifax

redux
DBname

dexfenfluramine
DBSynonym

dextrofenfluramine

(+)-fenfluramine

(s)-fenfluramine
Definition

The S-enantiomer of fenfluramine. It stimulates the release of serotonin and selectively inhibits its reuptake, but unlike fenfluramine it does not possess catecholamine agonist activity. It was formerly given by mouth as the hydrochloride in the treatment of obesity, but, like fenfluramine, was withdrawn wolrdwide following reports of valvular heart defects.
has pharmacological target

http://purl.obolibrary.org/obo/dinto_2714
has role

http://purl.obolibrary.org/obo/CHEBI_50949

http://purl.obolibrary.org/obo/CHEBI_35941

http://purl.obolibrary.org/obo/CHEBI_50507
InChI

InChI=1S/C12H16F3N/c1-3-16-9(2)7-10-5-4-6-11(8-10)12(13,14)15/h4-6,8-9,16H,3,7H2,1-2H3/t9-/m0/s1
InChIKey

InChIKey=DBGIVFWFUFKIQN-VIFPVBQESA-N
inhibits

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2714

http://purl.obolibrary.org/obo/dinto_2058

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0293

http://purl.obolibrary.org/obo/dinto_0291

http://purl.obolibrary.org/obo/dinto_2496
is metabolised by

http://purl.obolibrary.org/obo/dinto_2651

http://purl.obolibrary.org/obo/dinto_2993
label

(S)-fenfluramine
may interact with

http://purl.obolibrary.org/obo/dinto_DB01307

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_31981

http://purl.obolibrary.org/obo/dinto_DB00902

http://purl.obolibrary.org/obo/CHEBI_6838

http://purl.obolibrary.org/obo/CHEBI_8028

http://purl.obolibrary.org/obo/CHEBI_7936

http://purl.obolibrary.org/obo/dinto_DB01306

http://purl.obolibrary.org/obo/CHEBI_3647

http://purl.obolibrary.org/obo/CHEBI_8491

http://purl.obolibrary.org/obo/CHEBI_9711

http://purl.obolibrary.org/obo/dinto_DB01246

http://purl.obolibrary.org/obo/CHEBI_45951

http://purl.obolibrary.org/obo/CHEBI_6780

http://purl.obolibrary.org/obo/CHEBI_9566

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/CHEBI_8459

http://purl.obolibrary.org/obo/CHEBI_5123

http://purl.obolibrary.org/obo/CHEBI_2401

http://purl.obolibrary.org/obo/CHEBI_5138

http://purl.obolibrary.org/obo/CHEBI_8461

http://purl.obolibrary.org/obo/CHEBI_8435

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/CHEBI_5557

http://purl.obolibrary.org/obo/CHEBI_63620

http://purl.obolibrary.org/obo/CHEBI_313639

http://purl.obolibrary.org/obo/CHEBI_9544

http://purl.obolibrary.org/obo/CHEBI_5118

http://purl.obolibrary.org/obo/dinto_DB01309
prefixIRI

obo2:CHEBI_439329
prefLabel

(S)-fenfluramine
SMILES

CCN[C@@H](C)Cc1cccc(c1)C(F)(F)F

CCN[C@@H](C)CC1=CC=CC(=C1)C(F)(F)F
Synonym

dexfenfluramine

ethyl[(2S)-1-[3-(trifluoromethyl)phenyl]propan-2-yl]amine

(S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

(S)-fenfluramine

dextrofenfluramine

(+)-fenfluramine

(2S)-N-ethyl-1-[3-(trifluoromethyl)phenyl]propan-2-amine

dexfenfluramina

C12H16F3N

d-N-ethyl-alpha-methyl-m-trifluoromethylphenethylamine

dexfenfluraminum
xref

PharmGKB:PA164747936

ChEBI:439329

DrugBank:DB01191

RxList:http://www.rxlist.com/cgi/generic/dexfen.htm

KEGG DRUG:D07805

Wikipedia:http://en.wikipedia.org/wiki/Dexfenfluramine

CASRN:3239-44-9

Patent:US3198834

Beilstein:4783710

ChEMBL:16257207
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
Add comment
Add proposal
Delete Subject Author Type Created
No notes to display