08:18.08.20

CHEBI:520984

CHEBI:441792

CHEBI:525912

CHEBI:2360

CHEBI:193608

J05AF06

136470-78-5

ziagen

abacavir

(1S)-Cyclopent-2-en-1-ylmethanol in which the pro-R hydrogen at the 4-position is substituted by a 2-amino-6-(cyclopropylamino)-9H-purin-9-yl group. A nucleoside analogue reverse transcriptase inhibitor (NRTI) with antiretroviral activity against HIV, it is used (particularly as the sulfate) with other antiretrovirals in combination therapy of HIV infection.

InChI=1S/C14H18N6O/c15-14-18-12(17-9-2-3-9)11-13(19-14)20(7-16-11)10-4-1-8(5-10)6-21/h1,4,7-10,21H,2-3,5-6H2,(H3,15,17,18,19)/t8-,10+/m1/s1

InChIKey=MCGSCOLBFJQGHM-SCZZXKLOSA-N

abacavir

obo2:CHEBI_421707

abacavir

Nc1nc(NC2CC2)c2ncn([C@@H]3C[C@H](CO)C=C3)c2n1

NC1=NC2=C(N=CN2[C@@H]2C[C@H](CO)C=C2)C(NC2CC2)=N1

[(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl]methanol

{(1S,4R)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol

Abacavir

{(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol

abacavir

C14H18N6O

RxList:http://www.rxlist.com/cgi/generic/abavir.htm

ChEMBL:18029175

CiteXplore:18549801

Drugs Product Database (DPD):2240358

ChEMBL:16759112

Drugs.com:http://www.drugs.com/cdi/abacavir.html

KEGG DRUG:D07057

National Drug Code Directory:0173-0661-01

ChemSpider:58649

CASRN:136470-78-5

KEGG COMPOUND:C07624

PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/cx1527.shtml

ChEMBL:12781181

ChEMBL:17870541

PharmGKB:PA448004

PubChem Compound:441300

ChEMBL:15887959

ChEMBL:16458506

ChEBI:2360

Beilstein:7493116

ChEMBL:16539393

ChEMBL:17172311

Wikipedia:Abacavir

CiteXplore:11678376

DrugBank:DB01048

PubChem Substance:46505718

Wikipedia:http://en.wikipedia.org/wiki/Abacavir