The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016

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Preferred Name	allopurinol
Synonyms	4-HPP 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine C5H4N4O Allopurinol 1H-pyrazolo[3,4-d]pyrimidin-4-ol 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one 4'-Hydroxypyrazolol(3,4-d)pyrimidine 1H,2H,4H-pyrazolo[3,4-d]pyrimidin-4-one 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one Zyloprim (TN) Allopurinolum 4-Hydroxy-3,4-pyrazolopyrimidine 4-Hydroxypyrazolo(3,4-d)pyrimidine 4H-Pyrazolo(3,4-d)pyrimidin-4-one 1H-Pyrazolo(3,4-d)pyrimidin-4-ol Alopurinol 4-Hydroxypyrazolyl(3,4-d)pyrimidine AL-100 4-Hydroxypyrazolopyrimidine
ID	http://purl.obolibrary.org/obo/CHEBI_40279
AHFScode	92:00.00
altId	CHEBI:40276 CHEBI:2601
ATCCode	M04AA01
binds	http://purl.obolibrary.org/obo/dinto_3611 http://purl.obolibrary.org/obo/dinto_0273 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975
CASRN	315-30-0
DBBrand	allohexal anzief gotax allozym apurol anoprolin cosuric hexanuret hamarin nektrohan 7hp epidropal riball lopurin bloxanth epuric takanarumin dabrosin zyloprim urbol miniplanor monarch sigapurol apulonga lysuron adenock ketanrift aluline aloprim allo-puren apo-allopurinol urtias zyloric urosin remid atisuril embarin uritas caplenal urobenyl ketobun-a allopur bleminol dura al purinol urtias 100 foligan aloral suspendol uripurinol xanturat progout gichtex milurit hpp allural apurin urolit cellidrin dabroson uricemil ledopur ailural uriprim alositol geapur
DBname	allopurinol
DBSynonym	allopurinol sodium allopurinolum [inn-latin] alopurinol [inn-spanish]
Definition	A bicyclic structure comprising a pyrazole ring fused to a hydroxy-substituted pyrimidine ring.
has effect	http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000447 http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000497 http://purl.obolibrary.org/obo/OAE_0000453 http://purl.obolibrary.org/obo/OAE_0000905 http://purl.obolibrary.org/obo/OAE_0001098 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000902 http://purl.obolibrary.org/obo/OAE_0000882 http://purl.obolibrary.org/obo/OAE_0000391 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0001387 http://purl.obolibrary.org/obo/OAE_0000561 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0000493 http://purl.obolibrary.org/obo/OAE_0000411 http://purl.obolibrary.org/obo/OAE_0000921 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0000415 http://purl.obolibrary.org/obo/OAE_0000195 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000418 http://purl.obolibrary.org/obo/OAE_0000210 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000482 http://purl.obolibrary.org/obo/OAE_0001370 http://purl.obolibrary.org/obo/OAE_0000197 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000365 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000310 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0001538 http://purl.obolibrary.org/obo/OAE_0000608 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000612 http://purl.obolibrary.org/obo/OAE_0001055 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0001026 http://purl.obolibrary.org/obo/OAE_0001238 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000375 http://purl.obolibrary.org/obo/OAE_0001340 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0000498 http://purl.obolibrary.org/obo/OAE_0001515 http://purl.obolibrary.org/obo/OAE_0001425 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000286 http://purl.obolibrary.org/obo/OAE_0000086 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0002206 http://purl.obolibrary.org/obo/OAE_0001106 http://purl.obolibrary.org/obo/OAE_0000341 http://purl.obolibrary.org/obo/OAE_0000752 http://purl.obolibrary.org/obo/OAE_0000607 http://purl.obolibrary.org/obo/OAE_0000525 http://purl.obolibrary.org/obo/OAE_0000789 http://purl.obolibrary.org/obo/OAE_0000968 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000460 http://purl.obolibrary.org/obo/OAE_0000866 http://purl.obolibrary.org/obo/OAE_0000508 http://purl.obolibrary.org/obo/OAE_0000401 http://purl.obolibrary.org/obo/OAE_0000343 http://purl.obolibrary.org/obo/OAE_0000536 http://purl.obolibrary.org/obo/OAE_0001152 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0000602 http://purl.obolibrary.org/obo/OAE_0000487 http://purl.obolibrary.org/obo/OAE_0001147 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000396 http://purl.obolibrary.org/obo/OAE_0000390 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0001030 http://purl.obolibrary.org/obo/OAE_0000565 http://purl.obolibrary.org/obo/OAE_0001001 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000394 http://purl.obolibrary.org/obo/OAE_0000211 http://purl.obolibrary.org/obo/OAE_0000260 http://purl.obolibrary.org/obo/OAE_0001035 http://purl.obolibrary.org/obo/OAE_0000618 http://purl.obolibrary.org/obo/OAE_0001418 http://purl.obolibrary.org/obo/OAE_0000534 http://purl.obolibrary.org/obo/OAE_0001044 http://purl.obolibrary.org/obo/OAE_0001364 http://purl.obolibrary.org/obo/OAE_0000402 http://purl.obolibrary.org/obo/OAE_0000049 http://purl.obolibrary.org/obo/OAE_0000506 http://purl.obolibrary.org/obo/OAE_0000350 http://purl.obolibrary.org/obo/OAE_0000304
has pharmacological target	http://purl.obolibrary.org/obo/dinto_3611
has role	http://purl.obolibrary.org/obo/CHEBI_35634 http://purl.obolibrary.org/obo/CHEBI_35845 http://purl.obolibrary.org/obo/CHEBI_35221 http://purl.obolibrary.org/obo/CHEBI_48578
InChI	InChI=1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChIKey	InChIKey=OFCNXPDARWKPPY-UHFFFAOYSA-N
inhibits	http://purl.obolibrary.org/obo/dinto_3611
is metabolised by	http://purl.obolibrary.org/obo/dinto_3611 http://purl.obolibrary.org/obo/dinto_0273
is substrate of	http://purl.obolibrary.org/obo/dinto_3611 http://purl.obolibrary.org/obo/dinto_0273 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975
is transported by	http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975
label	allopurinol
may interact with	http://purl.obolibrary.org/obo/dinto_DB00519 http://purl.obolibrary.org/obo/CHEBI_2948 http://purl.obolibrary.org/obo/CHEBI_4031 http://purl.obolibrary.org/obo/CHEBI_53766 http://purl.obolibrary.org/obo/CHEBI_133809 http://purl.obolibrary.org/obo/CHEBI_10033 http://purl.obolibrary.org/obo/CHEBI_50667 http://purl.obolibrary.org/obo/CHEBI_4513
prefixIRI	obo2:CHEBI_40279
prefLabel	allopurinol
SMILES	Oc1ncnc2[nH]ncc12 O=C1N=CN=C2NNC=C12
Synonym	4-HPP 4-Hydroxy-1H-pyrazolo(3,4-d)pyrimidine C5H4N4O Allopurinol 1H-pyrazolo[3,4-d]pyrimidin-4-ol 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidin-4-one 4'-Hydroxypyrazolol(3,4-d)pyrimidine 1H,2H,4H-pyrazolo[3,4-d]pyrimidin-4-one 1,5-Dihydro-4H-pyrazolo(3,4-d)pyrimidine-4-one Zyloprim (TN) Allopurinolum 4-Hydroxy-3,4-pyrazolopyrimidine 4-Hydroxypyrazolo(3,4-d)pyrimidine 4H-Pyrazolo(3,4-d)pyrimidin-4-one 1H-Pyrazolo(3,4-d)pyrimidin-4-ol Alopurinol 4-Hydroxypyrazolyl(3,4-d)pyrimidine AL-100 4-Hydroxypyrazolopyrimidine
xref	PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/zyl1508.shtml CiteXplore:7602118 PDB:7HP Wikipedia:Allopurinol Drugs Product Database (DPD):555681 Beilstein:608611 Wikipedia:http://en.wikipedia.org/wiki/Allopurinol PubChem Compound:2094 DrugBank:DB00437 ChemSpider:2010 PubChem Substance:46508516 KEGG DRUG:D00224 RxList:http://www.rxlist.com/cgi/generic/allopur.htm National Drug Code Directory:55111-729-01 CASRN:315-30-0 BindingDB:50241255 PharmGKB:PA448320 ChEBI:40279 NIST Chemistry WebBook:315-30-0 ChEMBL:495607 Drugs.com:http://www.drugs.com/allopurinol.html
subClassOf	http://purl.obolibrary.org/obo/dinto_000055

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Mapping To	Ontology	Source
http://purl.obolibrary.org/obo/CHEBI_40279	OBA	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	DRON	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	PDRO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	FIDEO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	CCONT	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	HOIP	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	EFO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	BERO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	DDSS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	TXPO	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	BIOMODELS	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	CHEBI	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	NIFSTD	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	ODNAE	SAME_URI
http://purl.obolibrary.org/obo/CHEBI_40279	OBA	LOOM
http://purl.bioontology.org/ontology/ATC/M04AA01	ATC	LOOM
http://purl.bioontology.org/ontology/RXNORM/519	RXNORM	LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01931	MIO	LOOM
http://purl.bioontology.org/ontology/MESH/D000493	MESH	LOOM
http://www.co-ode.org/ontologies/galen#Allopurinol	GALEN	LOOM
http://purl.bioontology.org/ontology/RCD/j61..	RCD	LOOM
http://www.phoc.org.cn/pmo/class/PMO_00017791	PMAPP-PMO	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0002144	OCHV	LOOM
http://purl.bioontology.org/ontology/NDDF/001084	NDDF	LOOM
http://purl.obolibrary.org/obo/NCIT_C224	BERO	LOOM
http://purl.jp/bio/4/id/200906029513002976	IOBC	LOOM
http://stirdf.jst.go.jp/id/200907024219097332	IOBC	LOOM
http://purl.obolibrary.org/obo/MESH_D000493	BERO	LOOM
http://purl.obolibrary.org/obo/OMIT_0001912	OMIT	LOOM
http://purl.bioontology.org/ontology/SNMI/C-B7020	SNMI	LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387135004	SNOMEDCT	LOOM
http://www.drugbank.ca/drugs/DB00437	FTC	LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#917	OCHV	LOOM
http://purl.bioontology.org/ontology/LNC/MTHU024809	LOINC	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	DRON	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	PDRO	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	FIDEO	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	CCONT	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	HOIP	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	EFO	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	BERO	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	DDSS	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	TXPO	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	BIOMODELS	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	CHEBI	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	NIFSTD	LOOM
http://purl.obolibrary.org/obo/CHEBI_40279	ODNAE	LOOM
https://go.drugbank.com/drugs/DB00437	MDM	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.759.160	RH-MESH	LOOM
http://purl.bioontology.org/ontology/CSP/0875-2372	CRISP	LOOM
http://doe-generated-ontology.com/OntoAD#C0002144	ONTOAD	LOOM
http://purl.bioontology.org/ontology/VANDF/4017895	VANDF	LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C224	NCIT	LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D000493	RH-MESH	LOOM
http://purl.bioontology.org/ontology/LNC/LP17988-4	LOINC	LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146247	NDFRT	LOOM