loading...| Preferred Name |
colestipol |
|
| Synonyms |
C11H28ClN5O colestipolum Colestipol (2-aminoethyl)[2-({2-[(2-aminoethyl)amino]ethyl}amino)ethyl]amine; 2-(chloromethyl)oxirane |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_3814 |
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| AHFScode |
24:06.04 |
|
| ATCCode |
C10AC02 |
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| binds | ||
| CASRN |
50925-79-6 |
|
| DBBrand |
colestid cholestabyl |
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| DBname |
colestipol |
|
| DBSynonym |
colestipolum [inn-latin] |
|
| Definition |
A high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. Due to the highly cross-linked and insoluble nature of the material, no structural formula has been assigned and no specific molecular weight information is available. A basic anion exchange resin, it is used as its hydrochloride for binding bile acids in the intestine, inhibiting their reabsorption. |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C8H23N5.C3H5ClO/c9-1-3-11-5-7-13-8-6-12-4-2-10;4-1-3-2-5-3/h11-13H,1-10H2;3H,1-2H2 InChI=1S/C4H13N3.C3H5ClO/c5-1-3-7-4-2-6;4-1-3-2-5-3/h7H,1-6H2;3H,1-2H2 |
|
| InChIKey |
InChIKey=GMRWGQCZJGVHKL-UHFFFAOYSA-N InChIKey=WKSIFTCLOJYEOB-UHFFFAOYSA-N |
|
| label |
colestipol |
|
| prefixIRI |
obo2:CHEBI_3814 |
|
| prefLabel |
colestipol |
|
| SMILES |
ClCC1CO1.NCCNCCNCCNCCN |
|
| Synonym |
C11H28ClN5O colestipolum Colestipol (2-aminoethyl)[2-({2-[(2-aminoethyl)amino]ethyl}amino)ethyl]amine; 2-(chloromethyl)oxirane |
|
| xref |
CASRN:50925-79-6 Patent:US3692895 PharmGKB:PA449096 KEGG COMPOUND:C06925 PubChem Substance:46505777 National Drug Code Directory:59762-0260-1 PubChem Compound:62816 Drugs Product Database (DPD):642975 DrugBank:DB00375 ChemSpider:56550 Wikipedia:http://en.wikipedia.org/wiki/Colestipol Beilstein:9896237 Drugs.com:http://www.drugs.com/cdi/colestipol.html RxList:http://www.rxlist.com/cgi/generic/colestipol.htm PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/col1094.shtml Patent:US3803237 CASRN:26658-42-4 |
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| subClassOf |