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The Drug-Drug Interactions Ontology
| Preferred Name | vindesine | |
| Synonyms |
C43H55N5O7 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine methyl (5S,7S,9S)-9-[(2beta,3beta,4beta,5alpha,12beta,19alpha)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate methyl (13S,15S,17S)-13-[(1R,9R,10S,11R,12R,19R)-10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraene-13-carboxylate 3-(aminocarbonyl)-O(4)-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine 3-carbamoyl-O(4)-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine desacetylvinblastine amide |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_36373 |
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| ATCCode |
L01CA03
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|
| binds | ||
| CASRN |
59917-39-4
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|
| DBBrand |
dava eldesine eldisine
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| DBname |
vindesine
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|
| DBSynonym |
vindesine sulfate desacetylvinblastine amide sulfate
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| Definition |
A vinca alkaloid that has formula C43H55N5O7.
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C43H55N5O7/c1-6-39(52)21-25-22-42(38(51)55-5,33-27(13-17-47(23-25)24-39)26-11-8-9-12-30(26)45-33)29-19-28-31(20-32(29)54-4)46(3)35-41(28)15-18-48-16-10-14-40(7-2,34(41)48)36(49)43(35,53)37(44)50/h8-12,14,19-20,25,34-36,45,49,52-53H,6-7,13,15-18,21-24H2,1-5H3,(H2,44,50)/t25-,34+,35-,36-,39+,40-,41-,42+,43+/m1/s1
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| InChIKey |
InChIKey=HHJUWIANJFBDHT-KOTLKJBCSA-N
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|
| inhibits | ||
| is metabolised by | ||
| is substrate of | ||
| label |
vindesine
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|
| may interact with | ||
| prefixIRI |
obo2:CHEBI_36373
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| prefLabel |
vindesine
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| SMILES |
[H][C@@]12N3CC[C@@]11C4=CC(=C(OC)C=C4N(C)[C@@]1([H])[C@](O)([C@H](O)[C@]2(CC)C=CC3)C(N)=O)[C@]1(C[C@]2([H])CN(C[C@](O)(CC)C2)CCC2=C1NC1=CC=CC=C21)C(=O)OC [H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](O)[C@]2(CC)C=CC3)C(N)=O)[C@]1(C[C@@H]2C[N@](CCc3c1[nH]c1ccccc31)C[C@](O)(CC)C2)C(=O)OC
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| Synonym |
C43H55N5O7 3-carbamoyl-4-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine methyl (5S,7S,9S)-9-[(2beta,3beta,4beta,5alpha,12beta,19alpha)-3-carbamoyl-3,4-dihydroxy-16-methoxy-1-methyl-6,7-didehydroaspidospermidin-15-yl]-5-ethyl-5-hydroxy-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoazacycloundecino[5,4-b]indole-9-carboxylate methyl (13S,15S,17S)-13-[(1R,9R,10S,11R,12R,19R)-10-carbamoyl-12-ethyl-10,11-dihydroxy-5-methoxy-8-methyl-8,16-diazapentacyclo[10.6.1.0^{1,9}.0^{2,7}.0^{16,19}]nonadeca-2(7),3,5,13-tetraen-4-yl]-17-ethyl-17-hydroxy-1,11-diazatetracyclo[13.3.1.0^{4,12}.0^{5,10}]nonadeca-4(12),5,7,9-tetraene-13-carboxylate 3-(aminocarbonyl)-O(4)-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine 3-carbamoyl-O(4)-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine desacetylvinblastine amide
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| xref |
PharmGKB:PA10232 Wikipedia:http://en.wikipedia.org/wiki/Vindesine PubChem Substance:46504548 ChEMBL:465111 Beilstein:7162300 ChEBI:36373 DrugBank:DB00309 CASRN:53643-48-4 RxList:http://www.rxlist.com/cgi/generic2/vinor_cp.htm ChemSpider:37302 PubChem Compound:40839 Drugs Product Database (DPD):555665
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| subClassOf |
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