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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | cerivastatin sodium | |
| Synonyms |
C26H33FNNaO5 sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate (+)-sodium (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3559 |
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| Definition |
The sodium salt of cerivastatin. Formerly used to lower cholesterol and prevent cardiovascular disease, it was withdrawn from the market worldwide in 2001 following reports of a severe form of muscle toxicity.
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| has role | ||
| InChI |
InChI=1S/C26H34FNO5.Na/c1-15(2)25-21(11-10-19(29)12-20(30)13-23(31)32)24(17-6-8-18(27)9-7-17)22(14-33-5)26(28-25)16(3)4;/h6-11,15-16,19-20,29-30H,12-14H2,1-5H3,(H,31,32);/q;+1/p-1/b11-10+;/t19-,20-;/m1./s1
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| InChIKey |
InChIKey=GPUADMRJQVPIAS-QCVDVZFFSA-M
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| label |
cerivastatin sodium
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| prefixIRI |
obo2:CHEBI_3559
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| prefLabel |
cerivastatin sodium
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| SMILES |
[Na+].COCc1c(nc(C(C)C)c(\\C=C\\[C@@H](O)C[C@@H](O)CC([O-])=O)c1-c1ccc(F)cc1)C(C)C
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| Synonym |
C26H33FNNaO5 sodium (3R,5S,6E)-7-[4-(4-fluorophenyl)-5-(methoxymethyl)-2,6-di(propan-2-yl)pyridin-3-yl]-3,5-dihydroxyhept-6-enoate (+)-sodium (3R,5S,6E)-7-(4-(p-fluorophenyl)-2,6-diisopropyl-5-(methoxymethyl)-3-pyridyl)-3,5-dihydroxy-6-heptenoate
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| xref |
CASRN:143201-11-0 Patent:US5177080 DrugBank:DB00439 ChEMBL:774514 KEGG DRUG:D00889 Beilstein:8466341
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