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The Drug-Drug Interactions Ontology
| Preferred Name | ceftazidime | |
| Synonyms |
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate ceftazidimum ceftazidime 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium C22H22N6O7S2 CAZ Ceftazidime anhydrous (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ceftazidima |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_3508 |
|
| AHFScode |
08:12.06.12
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|
| ATCCode |
J01DD02
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|
| binds |
http://purl.obolibrary.org/obo/dinto_2967 http://purl.obolibrary.org/obo/dinto_2964 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_0758 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_1854 http://purl.obolibrary.org/obo/dinto_3095 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_0081 http://purl.obolibrary.org/obo/dinto_3995 http://purl.obolibrary.org/obo/dinto_0360 |
|
| CASRN |
78439-06-2
|
|
| DBBrand |
ceftazidime sodium in plastic container ceftazidime pentahydrate ceftazidima [inn-spanish] tazicef tazidime pentacef ceptaz tazidime in plastic container fortaz fortaz in plastic container ceftazidimum [inn-latin]
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|
| DBname |
ceftazidime
|
|
| Definition |
A cephalosporin bearing pyridinium-1-ylmethyl and {[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetamido groups at positions 3 and 7, respectively, of the cephem skeleton.
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|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000449 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000376 http://purl.obolibrary.org/obo/OAE_0000825 http://purl.obolibrary.org/obo/OAE_0001449 http://purl.obolibrary.org/obo/OAE_0001333 http://purl.obolibrary.org/obo/OAE_0001707 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000770 http://purl.obolibrary.org/obo/OAE_0000454 http://purl.obolibrary.org/obo/OAE_0000287 http://purl.obolibrary.org/obo/OAE_0000690 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0001463 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0001275 http://purl.obolibrary.org/obo/OAE_0001243 http://purl.obolibrary.org/obo/OAE_0000268 http://purl.obolibrary.org/obo/OAE_0000494 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000584 http://purl.obolibrary.org/obo/OAE_0001129 http://purl.obolibrary.org/obo/OAE_0000194 http://purl.obolibrary.org/obo/OAE_0001152 http://purl.obolibrary.org/obo/OAE_0000491 http://purl.obolibrary.org/obo/OAE_0000468 http://purl.obolibrary.org/obo/OAE_0001217 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0001366 http://purl.obolibrary.org/obo/OAE_0001364 |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_2967 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_0758 http://purl.obolibrary.org/obo/dinto_1854 http://purl.obolibrary.org/obo/dinto_3095 http://purl.obolibrary.org/obo/dinto_0081 |
|
| has role | ||
| InChI |
InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/b26-13-/t14-,18-/m1/s1
|
|
| InChIKey |
InChIKey=ORFOPKXBNMVMKC-DWVKKRMSSA-N
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|
| inhibits |
http://purl.obolibrary.org/obo/dinto_2967 http://purl.obolibrary.org/obo/dinto_2964 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_0758 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_1854 http://purl.obolibrary.org/obo/dinto_3095 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_0081 http://purl.obolibrary.org/obo/dinto_3995 http://purl.obolibrary.org/obo/dinto_0360 |
|
| label |
ceftazidime
|
|
| may interact with |
http://purl.obolibrary.org/obo/dinto_DB00994 http://purl.obolibrary.org/obo/dinto_DB01172 http://purl.obolibrary.org/obo/dinto_DB00798 http://purl.obolibrary.org/obo/CHEBI_17076 http://purl.obolibrary.org/obo/dinto_DB00955 |
|
| prefixIRI |
obo2:CHEBI_3508
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|
| prefLabel |
ceftazidime
|
|
| SMILES |
[H][C@]12SCC(C[n+]3ccccc3)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC(C)(C)C(O)=O)\\c1csc(N)n1)C([O-])=O [O-]C(=O)C1=C(CS[C@]2([H])[C@H](NC(=O)C(=N/OC(C)(C)C(O)=O)\C3=CSC(N)=N3)C(=O)N12)C[N+]1=CC=CC=C1
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| Synonym |
7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-3-(pyridinium-1-ylmethyl)-3,4-didehydrocepham-4-carboxylate ceftazidimum ceftazidime 1-{[(6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetamido]-2-carboxylato-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl}pyridin-1-ium C22H22N6O7S2 CAZ Ceftazidime anhydrous (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino}-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate ceftazidima
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| xref |
ChemSpider:4587145 CiteXplore:12120880 CiteXplore:12048030 KEGG DRUG:D07654 PubChem Compound:5481173 Wikipedia:http://en.wikipedia.org/wiki/Ceftazidime CiteXplore:12833570 ChEMBL:161682 CiteXplore:11605815 Wikipedia:Ceftazidime Patent:DE2921316 CiteXplore:15913752 CiteXplore:16092041 Reaxys:5475149 KEGG COMPOUND:C06889 CiteXplore:18926104 CiteXplore:15618675 Beilstein:5475149 CiteXplore:1991925 Patent:US4258041 Drugs Product Database (DPD):886963 National Drug Code Directory:25021-127-20 ChEBI:3508 CiteXplore:15687217 PDB:CAZ CiteXplore:16956383 RxList:http://www.rxlist.com/cgi/generic2/ceftaz.htm CiteXplore:14961139 CASRN:72558-82-8 CiteXplore:19810175 CiteXplore:1384868 CiteXplore:11284241 CiteXplore:12523657 DrugBank:DB00438 CiteXplore:2068466 CiteXplore:11815759 PubChem Substance:46506143 CiteXplore:18611568 CiteXplore:11591698 CiteXplore:16501927 CiteXplore:11252323 PharmGKB:PA448861 CiteXplore:15528892 Drugs.com:http://www.drugs.com/cdi/ceftazidime.html
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| subClassOf |
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