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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | cefpodoxime | |
| Synonyms |
cefpodoxime cefpodoximum 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid C15H17N5O6S2 (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefpodoxima (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_3504 |
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| altId |
CHEBI:606443
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| ATCCode |
J01DD13
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| binds | ||
| CASRN |
82619-04-3
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| DBBrand |
vantin banan doxef
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| DBname |
cefpodoxime
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| DBSynonym |
ru 51807 cpdx-pr cefpodoxime proxetil
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| Definition |
A third-generation cephalosporin antibiotic with methoxymethyl and (2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamino substituents at positions 3 and 7, respectively, of the cephem skeleton. Given by mouth as its proxetil ester prodrug, it is used to treat acute otitis media, pharyngitis, and sinusitis.
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| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C15H17N5O6S2/c1-25-3-6-4-27-13-9(12(22)20(13)10(6)14(23)24)18-11(21)8(19-26-2)7-5-28-15(16)17-7/h5,9,13H,3-4H2,1-2H3,(H2,16,17)(H,18,21)(H,23,24)/b19-8-/t9-,13-/m1/s1
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| InChIKey |
InChIKey=WYUSVOMTXWRGEK-HBWVYFAYSA-N
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| inhibits | ||
| label |
cefpodoxime
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|
| prefixIRI |
obo2:CHEBI_3504
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| prefLabel |
cefpodoxime
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| SMILES |
[H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\C1=CSC(N)=N1)C(O)=O [H][C@]12SCC(COC)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\\c1csc(N)n1)C(O)=O
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| Synonym |
cefpodoxime cefpodoximum 7beta-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-3,4-didehydrocepham-4-carboxylic acid C15H17N5O6S2 (6R,7R)-7-[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefpodoxima (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-(methoxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
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| xref |
CiteXplore:20606336 PubChem Compound:6335986 National Drug Code Directory:0009-3617-01 CiteXplore:21395603 PharmGKB:PA164746385 CiteXplore:21569093 Wikipedia:http://en.wikipedia.org/wiki/Cefpodoxime CASRN:80210-62-4 PubChem Substance:46504897 DrugBank:DB01416 Beilstein:6021381 CiteXplore:21420838 Drugs.com:http://www.drugs.com/cdi/cefpodoxime.html CiteXplore:21509928 Reaxys:6021381 Wikipedia:Cefpodoxime RxList:http://www.rxlist.com/cgi/generic/vantin.htm CiteXplore:21667000 ChemSpider:4891496 CiteXplore:21455420 CiteXplore:20821175 KEGG COMPOUND:C08114 KEGG DRUG:D07650
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| subClassOf |
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