| Synonyms |
BUTORPHANOL
Butorphanol
butorfanol
butorphanol
(-)-17-(cyclobutylmethyl)morphinan-3,14-diol
17-(cyclobutylmethyl)morphinan-3,14-diol
C21H29NO2
(-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan
butorphanolum
(1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4,10-diol
(-)-butorphanol
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| Definition |
Levorphanol in which a hydrogen at position 14 of the morphinan skeleton is substituted by hydroxy and one of the hydrogens of the N-methyl group is substituted by cyclopropyl. A semi-synthetic opioid agonist-antagonist analgesic, it is used as its (S,S)-tartaric acid salt for relief or moderate to severe pain.
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| InChI |
InChI=1S/C21H29NO2/c23-17-7-6-16-12-19-21(24)9-2-1-8-20(21,18(16)13-17)10-11-22(19)14-15-4-3-5-15/h6-7,13,15,19,23-24H,1-5,8-12,14H2/t19-,20+,21-/m1/s1
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| Synonym |
BUTORPHANOL Butorphanol butorfanol butorphanol (-)-17-(cyclobutylmethyl)morphinan-3,14-diol 17-(cyclobutylmethyl)morphinan-3,14-diol C21H29NO2 (-)-N-cyclobutylmethyl-3,14-dihydroxymorphinan butorphanolum (1S,9R,10S)-17-(cyclobutylmethyl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-triene-4,10-diol (-)-butorphanol
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| xref |
DrugBank:DB00611 ChEMBL:6166748 ChEBI:3242 Patent:US3775414 Beilstein:8134188 CASRN:42408-82-2 ChEMBL:6114178 Patent:US3819635 ChemSpider:4514667 Patent:DE2243961 Wikipedia:Butorphanol Drugs.com:http://www.drugs.com/cdi/butorphanol-solution.html National Drug Code Directory:0378-9639-43 RxList:http://www.rxlist.com/cgi/generic2/butor.htm PubChem Substance:46507553 KEGG DRUG:D03197 ChEMBL:6796691 BindingDB:50240437 PubChem Compound:6916249 ChEMBL:6767032 ChEMBL:7192744 Wikipedia:http://en.wikipedia.org/wiki/Butorphanol Drugs Product Database (DPD):844977 KEGG COMPOUND:C06863 PharmGKB:PA164745398
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