The Drug-Drug Interactions Ontology

Last uploaded: February 11, 2016
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Preferred Name

buspirone
Synonyms

8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione

buspirone

Buspirone

buspironum

8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione

8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione

buspirona

C21H31N5O2
ID

http://purl.obolibrary.org/obo/CHEBI_3223
AHFScode

28:24.92
ATCCode

N05BE01
binds

http://purl.obolibrary.org/obo/dinto_1440

http://purl.obolibrary.org/obo/dinto_1166

http://purl.obolibrary.org/obo/dinto_2804

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1956
blocks

http://purl.obolibrary.org/obo/dinto_2804
CASRN

36505-84-7
DBBrand

ansiced

censpar

buspinol

lucelan

buspar

narol

ansial

anxiron

bespar

travin

buspimen

buspisal

axoren
DBname

buspirone
DBSynonym

buspironum [inn-latin]

buspirone hcl

buspirona [inn-spanish]
Definition

An azaspiro compound that has formula C21H31N5O2.
has effect

http://purl.obolibrary.org/obo/OAE_0000785

http://purl.obolibrary.org/obo/OAE_0000395

http://purl.obolibrary.org/obo/OAE_0000303

http://purl.obolibrary.org/obo/OAE_0000377

http://purl.obolibrary.org/obo/OAE_0000902

http://purl.obolibrary.org/obo/OAE_0000630

http://purl.obolibrary.org/obo/OAE_0000218

http://purl.obolibrary.org/obo/OAE_0000376

http://purl.obolibrary.org/obo/OAE_0000335

http://purl.obolibrary.org/obo/OAE_0000406

http://purl.obolibrary.org/obo/OAE_0000561

http://purl.obolibrary.org/obo/OAE_0001509

http://purl.obolibrary.org/obo/OAE_0001186

http://purl.obolibrary.org/obo/OAE_0000921

http://purl.obolibrary.org/obo/OAE_0000512

http://purl.obolibrary.org/obo/OAE_0001489

http://purl.obolibrary.org/obo/OAE_0001360

http://purl.obolibrary.org/obo/OAE_0000415

http://purl.obolibrary.org/obo/OAE_0000373

http://purl.obolibrary.org/obo/OAE_0000319

http://purl.obolibrary.org/obo/OAE_0001448

http://purl.obolibrary.org/obo/OAE_0000333

http://purl.obolibrary.org/obo/OAE_0000250

http://purl.obolibrary.org/obo/OAE_0001339

http://purl.obolibrary.org/obo/OAE_0000600

http://purl.obolibrary.org/obo/OAE_0000310

http://purl.obolibrary.org/obo/OAE_0000920

http://purl.obolibrary.org/obo/OAE_0000403

http://purl.obolibrary.org/obo/OAE_0000601

http://purl.obolibrary.org/obo/OAE_0000551

http://purl.obolibrary.org/obo/OAE_0001515

http://purl.obolibrary.org/obo/OAE_0000309

http://purl.obolibrary.org/obo/OAE_0000400

http://purl.obolibrary.org/obo/OAE_0000586

http://purl.obolibrary.org/obo/OAE_0000510

http://purl.obolibrary.org/obo/OAE_0000645

http://purl.obolibrary.org/obo/OAE_0000584

http://purl.obolibrary.org/obo/OAE_0001129

http://purl.obolibrary.org/obo/OAE_0000842

http://purl.obolibrary.org/obo/OAE_0000643

http://purl.obolibrary.org/obo/OAE_0000542

http://purl.obolibrary.org/obo/OAE_0000894

http://purl.obolibrary.org/obo/OAE_0000607

http://purl.obolibrary.org/obo/OAE_0000355

http://purl.obolibrary.org/obo/OAE_0000038

http://purl.obolibrary.org/obo/OAE_0000034

http://purl.obolibrary.org/obo/OAE_0000166

http://purl.obolibrary.org/obo/OAE_0000460

http://purl.obolibrary.org/obo/OAE_0000508

http://purl.obolibrary.org/obo/OAE_0000780

http://purl.obolibrary.org/obo/OAE_0000536

http://purl.obolibrary.org/obo/OAE_0001336

http://purl.obolibrary.org/obo/OAE_0000385

http://purl.obolibrary.org/obo/OAE_0000602

http://purl.obolibrary.org/obo/OAE_0000779

http://purl.obolibrary.org/obo/OAE_0000396

http://purl.obolibrary.org/obo/OAE_0000275

http://purl.obolibrary.org/obo/OAE_0000390

http://purl.obolibrary.org/obo/OAE_0000362

http://purl.obolibrary.org/obo/OAE_0000470

http://purl.obolibrary.org/obo/OAE_0000374

http://purl.obolibrary.org/obo/OAE_0000394

http://purl.obolibrary.org/obo/OAE_0000313

http://purl.obolibrary.org/obo/OAE_0000534
has pharmacological target

http://purl.obolibrary.org/obo/dinto_2804

http://purl.obolibrary.org/obo/dinto_1166
has role

http://purl.obolibrary.org/obo/CHEBI_35474

http://purl.obolibrary.org/obo/CHEBI_35941

http://purl.obolibrary.org/obo/CHEBI_35717
InChI

InChI=1S/C21H31N5O2/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20/h5,8-9H,1-4,6-7,10-17H2
InChIKey

InChIKey=QWCRAEMEVRGPNT-UHFFFAOYSA-N
inhibits

http://purl.obolibrary.org/obo/dinto_1440
is metabolised by

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1956
is substrate of

http://purl.obolibrary.org/obo/dinto_2990

http://purl.obolibrary.org/obo/dinto_2993

http://purl.obolibrary.org/obo/dinto_0901

http://purl.obolibrary.org/obo/dinto_1956
label

buspirone
may interact with

http://purl.obolibrary.org/obo/CHEBI_9948

http://purl.obolibrary.org/obo/CHEBI_9943

http://purl.obolibrary.org/obo/CHEBI_101278

http://purl.obolibrary.org/obo/dinto_DB00726

http://purl.obolibrary.org/obo/CHEBI_7494

http://purl.obolibrary.org/obo/dinto_DB00780

http://purl.obolibrary.org/obo/CHEBI_9654

http://purl.obolibrary.org/obo/dinto_DB00582

http://purl.obolibrary.org/obo/CHEBI_3732

http://purl.obolibrary.org/obo/CHEBI_45367

http://purl.obolibrary.org/obo/dinto_DB01247

http://purl.obolibrary.org/obo/dinto_DB00752

http://purl.obolibrary.org/obo/CHEBI_63620

http://purl.obolibrary.org/obo/dinto_DB00199

http://purl.obolibrary.org/obo/dinto_DB00503

http://purl.obolibrary.org/obo/CHEBI_31739

http://purl.obolibrary.org/obo/CHEBI_10124

http://purl.obolibrary.org/obo/CHEBI_28077

http://purl.obolibrary.org/obo/dinto_DB00976

http://purl.obolibrary.org/obo/dinto_DB06700
modulates

http://purl.obolibrary.org/obo/dinto_2804
prefixIRI

obo2:CHEBI_3223
prefLabel

buspirone
related with

http://purl.obolibrary.org/obo/dinto_1166
SMILES

O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)C1=NC=CC=N1

O=C1CC2(CCCC2)CC(=O)N1CCCCN1CCN(CC1)c1ncccn1
Synonym

8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione

buspirone

Buspirone

buspironum

8-(4-(4-(2-Pyrimidinyl)-1-piperizinyl)butyl)-8-azaspiro(4,5)decane-7,9-dione

8-{4-[4-(pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione

buspirona

C21H31N5O2
xref

CASRN:36505-84-7

KEGG DRUG:D07593

Patent:DE2057845

Wikipedia:Buspirone

ChemSpider:2383

PharmGKB:PA448689

Patent:US3717634

Drugs.com:http://www.drugs.com/buspirone.html

RxList:http://www.rxlist.com/cgi/generic/buspir.htm

Guide To Pharmacology:36

PubChem Substance:46508113

KEGG COMPOUND:C06861

Drugs Product Database (DPD):2242149

ChEMBL:103599

Beilstein:964904

ChEBI:3223

Wikipedia:http://en.wikipedia.org/wiki/Buspirone

DrugBank:DB00490

PubChem Compound:2477

National Drug Code Directory:0378-1140-01

IUPHAR:36
subClassOf

http://purl.obolibrary.org/obo/dinto_000055
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Mapping To Ontology Source
http://purl.obolibrary.org/obo/CHEBI_3223 DRON SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 PDRO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 FIDEO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 CCONT SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 CHEBI SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 BERO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 DDSS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 BIOMODELS SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 NIFSTD SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 EFO SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 ODNAE SAME_URI
http://purl.obolibrary.org/obo/CHEBI_3223 OBA SAME_URI
http://purl.obolibrary.org/obo/NCIT_C62013 BERO LOOM
http://ontology.apa.org/apaonto/termsonlyOUT%20(5).owl#Buspirone APAONTO LOOM
http://purl.obolibrary.org/obo/MESH_D002065 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 FIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 CCONT LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 DDSS LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 EFO LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 ODNAE LOOM
http://purl.obolibrary.org/obo/CHEBI_3223 OBA LOOM
http://purl.bioontology.org/ontology/CSP/4000-0133 CRISP LOOM
http://purl.bioontology.org/ontology/VANDF/4019646 VANDF LOOM
http://purl.jp/bio/4/id/200906092539845452 IOBC LOOM
http://www.semanticweb.org/administrator/ontologies/2022/0/untitled-ontology-34#OWLClass4f27d3a3_7013_4343_bce6_115918d87f26 WWECA LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#2244 OCHV LOOM
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62013 NCIT LOOM
http://www.drugbank.ca/drugs/DB00490 FTC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387523009 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Buspirone GALEN LOOM
http://www.phoc.org.cn/pmo/class/PMO_00016975 PMAPP-PMO LOOM
http://evs.nci.nih.gov/ftp1/NDF-RT/NDF-RT.owl#N0000147739 ODAE LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.455.426.559.847.885.120 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907031039222429 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0003414 OMIT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.383.742.120 RH-MESH LOOM
https://go.drugbank.com/drugs/DB00490 MDM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.885.120 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU063033 LOINC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0006462 OCHV LOOM
http://purl.bioontology.org/ontology/ATC/N05BE01 ATC LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000147739 NDFRT LOOM
http://purl.bioontology.org/ontology/SNMI/C-64210 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D002065 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/LP17859-7 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/1827 RXNORM LOOM
http://purl.bioontology.org/ontology/MESH/D002065 MESH LOOM
http://purl.bioontology.org/ontology/NDDF/004586 NDDF LOOM
http://purl.bioontology.org/ontology/RCD/x01BH RCD LOOM