loading...| Preferred Name |
midodrine hydrochloride |
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| Synonyms |
C12H19ClN2O4 rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide hydrochloride (+-)-Midodrine hydrochloride C12H18N2O4.HCl Midodrine HCl (+-)-1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide monohydrochloride Pro-Amatine ProAmatine |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_31847 |
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| Definition |
A hydrochloride resulting from the combination of equimolar amounts of midodrine and hydrogen chloride. Midodrine is a direct-acting sympathomimetic with selective alpha-adrenergic agonist activity. The hydrochloride salt is used as a peripheral vasoconstrictor in the treatment of certain hypotensive states. The main active moiety is its major metabolite, deglymidodrine. |
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| has role |
http://purl.obolibrary.org/obo/CHEBI_35524 |
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| InChI |
InChI=1S/C12H18N2O4.ClH/c1-17-8-3-4-11(18-2)9(5-8)10(15)7-14-12(16)6-13;/h3-5,10,15H,6-7,13H2,1-2H3,(H,14,16);1H |
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| InChIKey |
InChIKey=MGCQZNBCJBRZDT-UHFFFAOYSA-N |
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| label |
midodrine hydrochloride |
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| prefixIRI |
obo2:CHEBI_31847 |
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| prefLabel |
midodrine hydrochloride |
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| SMILES |
Cl.COc1ccc(OC)c(c1)C(O)CNC(=O)CN |
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| Synonym |
C12H19ClN2O4 rac-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]glycinamide hydrochloride (+-)-Midodrine hydrochloride C12H18N2O4.HCl Midodrine HCl (+-)-1-(2',5'-Dimethoxyphenyl)-2-glycinamidoethanol hydrochloride (+-)-2-Amino-N-(beta-hydroxy-2,5-dimethoxyphenethyl)acetamide monohydrochloride Pro-Amatine ProAmatine |
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| xref |
CiteXplore:21301135 DrugBank:DB00211 ChEMBL:774412 Patent:WO2004018409 HMDB:HMDB14356 KEGG DRUG:D01307 Reaxys:6579688 CiteXplore:20801263 CASRN:3092-17-9 |
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| subClassOf |