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The Drug-Drug Interactions Ontology
Last uploaded:
February 11, 2016
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| Preferred Name | formoterol fumarate | |
| Synonyms |
C19H24N2O4 rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide formoterol hemifumarate rac-bis[(2R)-N-{(2R)-2-[3-(formylamino)-4-hydroxyphenyl]-2-hydroxyethyl}-1-(4-methoxyphenyl)propan-2-aminium] (2E)-but-2-enedioate |
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| ID |
http://purl.obolibrary.org/obo/CHEBI_31633 |
|
| activates | ||
| AHFScode |
12:12.08.12
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|
| ATCCode |
R03AC13
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|
| binds |
http://purl.obolibrary.org/obo/dinto_3504 http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 |
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| CASRN |
73573-87-2
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|
| DBBrand |
foradile oxis oxeze turbuhaler foradil foradil oxeze turbuhaler
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|
| DBname |
formoterol
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|
| DBSynonym |
formoterolum [inn-latin] formoterol fumarate
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|
| Definition |
A racemate consisting of equal amounts of arformoterol fumarate (the active enantiomer) and (S,S)-formoterol fumarate (the inactive enantiomer). It is used (particularly in its dihydrate form) as a direct-acting sympathomimetic and bronchodilator for the treatment of chronic obstructive pulmonary disease (any progressive respiratory disease that makes it harder to breathe over time, such as chronic bronchitis and emphysema).
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|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_35522 |
|
| InChI |
InChI=1S/C19H24N2O4/c1-13(9-14-3-6-16(25-2)7-4-14)20-11-19(24)15-5-8-18(23)17(10-15)21-12-22/h3-8,10,12-13,19-20,23-24H,9,11H2,1-2H3,(H,21,22)
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|
| InChIKey |
InChIKey=BPZSYCZIITTYBL-UHFFFAOYSA-N
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|
| is metabolised by |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 |
|
| is substrate of |
http://purl.obolibrary.org/obo/dinto_2058 http://purl.obolibrary.org/obo/dinto_2993 |
|
| label |
formoterol fumarate
|
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_31633
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|
| prefLabel |
formoterol fumarate
|
|
| SMILES |
COC1=CC=C(CC(C)NCC(O)C2=CC(NC=O)=C(O)C=C2)C=C1
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|
| Synonym |
C19H24N2O4 rac-N-{2-hydroxy-5-[(1R)-1-hydroxy-2-{[(2R)-1-(4-methoxyphenyl)propan-2-yl]amino}ethyl]phenyl}formamide (2E)-but-2-enedioate N-[2-hydroxy-5-(1-hydroxy-2-{[1-(4-methoxyphenyl)propan-2-yl]amino}ethyl)phenyl]formamide formoterol hemifumarate rac-bis[(2R)-N-{(2R)-2-[3-(formylamino)-4-hydroxyphenyl]-2-hydroxyethyl}-1-(4-methoxyphenyl)propan-2-aminium] (2E)-but-2-enedioate
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|
| xref |
CiteXplore:18655841 PubChem Compound:3410 Drugs Product Database (DPD):2237225 RxList:http://www.rxlist.com/cgi/generic/foradil.htm CiteXplore:20477569 KEGG DRUG:D01373 IUPHAR:3465 DrugBank:DB00983 PubChem Substance:46507099 CASRN:43229-80-7 ChemSpider:3292 Wikipedia:http://en.wikipedia.org/wiki/Formoterol Guide To Pharmacology:3465 National Drug Code Directory:0085-1402-01 Drugs.com:http://www.drugs.com/cdi/formoterol.html PharmGKB:PA134687907 Reaxys:8463050
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| subClassOf |
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