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The Drug-Drug Interactions Ontology
| Preferred Name | amikacin | |
| Synonyms |
(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide C22H43N5O13 Amikacin amikacina O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine amikacin amikacine amikacinum 1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_2637 |
|
| AHFScode |
08:12.02
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|
| ATCCode |
J01GB06 S01AA21 D06AX12
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|
| binds | ||
| CASRN |
37517-28-5
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|
| DBBrand |
amikavet amiglyde-v briclin amikin amicacin
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|
| DBname |
amikacin
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|
| DBSynonym |
amikacin dihydrate bb-k8 amikacin base amikacine [inn-french] amikacinum [inn-latin] amikacin sulfate antibiotic bb-k8 amikacina [inn-spanish]
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|
| Definition |
An alpha-D-glucoside that has formula C22H43N5O13.
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|
| has effect |
http://purl.obolibrary.org/obo/OAE_0001059 http://purl.obolibrary.org/obo/OAE_0000573 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0000577 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001365 http://purl.obolibrary.org/obo/OAE_0000920 http://purl.obolibrary.org/obo/OAE_0000539 http://purl.obolibrary.org/obo/OAE_0000601 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000166 http://purl.obolibrary.org/obo/OAE_0000385 http://purl.obolibrary.org/obo/OAE_0000362 |
|
| has pharmacological target | ||
| has role | ||
| InChI |
InChI=1S/C22H43N5O13/c23-2-1-8(29)20(36)27-7-3-6(25)18(39-22-16(34)15(33)13(31)9(4-24)37-22)17(35)19(7)40-21-14(32)11(26)12(30)10(5-28)38-21/h6-19,21-22,28-35H,1-5,23-26H2,(H,27,36)/t6-,7+,8-,9+,10+,11-,12+,13+,14+,15-,16+,17-,18+,19-,21+,22+/m0/s1
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|
| InChIKey |
InChIKey=LKCWBDHBTVXHDL-RMDFUYIESA-N
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|
| inhibits | ||
| label |
amikacin
|
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_553473 http://purl.obolibrary.org/obo/CHEBI_3213 http://purl.obolibrary.org/obo/CHEBI_9939 http://purl.obolibrary.org/obo/CHEBI_3499 http://purl.obolibrary.org/obo/CHEBI_3491 http://purl.obolibrary.org/obo/CHEBI_3493 http://purl.obolibrary.org/obo/CHEBI_3495 http://purl.obolibrary.org/obo/dinto_DB01338 http://purl.obolibrary.org/obo/CHEBI_3480 http://purl.obolibrary.org/obo/CHEBI_474053 http://purl.obolibrary.org/obo/CHEBI_61049 http://purl.obolibrary.org/obo/CHEBI_9513 http://purl.obolibrary.org/obo/dinto_DB01336 http://purl.obolibrary.org/obo/dinto_DB01226 http://purl.obolibrary.org/obo/dinto_DB00214 http://purl.obolibrary.org/obo/CHEBI_45652 http://purl.obolibrary.org/obo/CHEBI_204928 http://purl.obolibrary.org/obo/CHEBI_3508 http://purl.obolibrary.org/obo/CHEBI_124991 http://purl.obolibrary.org/obo/CHEBI_29007 http://purl.obolibrary.org/obo/dinto_DB01112 http://purl.obolibrary.org/obo/CHEBI_554446 http://purl.obolibrary.org/obo/CHEBI_8884 http://purl.obolibrary.org/obo/CHEBI_7907 http://purl.obolibrary.org/obo/CHEBI_9774 http://purl.obolibrary.org/obo/CHEBI_209807 http://purl.obolibrary.org/obo/CHEBI_2914 http://purl.obolibrary.org/obo/CHEBI_9587 http://purl.obolibrary.org/obo/CHEBI_4876 http://purl.obolibrary.org/obo/CHEBI_59662 http://purl.obolibrary.org/obo/CHEBI_47426 http://purl.obolibrary.org/obo/CHEBI_27899 |
|
| prefixIRI |
obo2:CHEBI_2637
|
|
| prefLabel |
amikacin
|
|
| SMILES |
NCC[C@H](O)C(=O)N[C@@H]1C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)[C@@H](O)[C@H](O)[C@H]2O)[C@H](O)[C@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](N)[C@H]1O
|
|
| Synonym |
(2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-{[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-4-{[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxyoxan-2-yl]oxy}-3-hydroxycyclohexyl]-2-hydroxybutanamide (2S)-4-amino-N-[(1R,2S,3S,4R,5S)-5-amino-2-(3-amino-3-deoxy-alpha-D-glucopyranosyloxy)-4-(6-amino-6-deoxy-alpha-D-glucopyranosyloxy)-3-hydroxycyclohexyl]-2-hydroxybutanamide C22H43N5O13 Amikacin amikacina O-3-amino-3-deoxy-alpha-D-glucopyranosyl-(1->4)-O-(6-amino-6-deoxy-alpha-D-glucopyranosyl-(1->6))-N(3)-(4-amino-L-2-hydroxybutyryl)-2-deoxy-L-streptamine amikacin amikacine amikacinum 1-N-(L(-)-gamma-amino-alpha-hydroxybutyryl)kanamycin A
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|
| xref |
ChEBI:2637 Drugs.com:http://www.drugs.com/cdi/amikacin.html Wikipedia:http://en.wikipedia.org/wiki/Amikacin KEGG DRUG:D02543 PharmGKB:PA164744372 ChemSpider:34635 ChEMBL:433157 National Drug Code Directory:0703-9032-03 PubChem Compound:37768 Wikipedia:Amikacin PubChem Substance:46506386 Patent:US3781268 DrugBank:DB00479 RxList:http://www.rxlist.com/cgi/generic3/amikacin.htm KEGG COMPOUND:C06820 Beilstein:5915117 CASRN:37517-28-5 Drugs Product Database (DPD):2242971 Patent:DE2234315
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| subClassOf |
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