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The Drug-Drug Interactions Ontology
| Preferred Name | prostaglandin E1 | |
| Synonyms |
C20H34O5 (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate Caverject Prostin VR (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid PGE-1 Edex Muse Befar alprostadil 11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid (13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid PGE1 Alprostadil alprostadilum Prostaglandin E1 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_15544 |
|
| activates | ||
| AHFScode |
24:12.92
|
|
| altId |
CHEBI:142 CHEBI:10820 CHEBI:26322
|
|
| ATCCode |
G04BE01 C01EA01
|
|
| binds |
http://purl.obolibrary.org/obo/dinto_1992 http://purl.obolibrary.org/obo/dinto_1322 http://purl.obolibrary.org/obo/dinto_1763 http://purl.obolibrary.org/obo/dinto_0554 http://purl.obolibrary.org/obo/dinto_0970 |
|
| CASRN |
745-65-3
|
|
| DBBrand |
caverject prink alprox-td befar alista pge1 l-prostaglandin e1 femprox alprostadil prostoglandin e1 topiglan muse edex prostaglandin e1 prostin vr pediatric prostin vr
|
|
| DBname |
alprostadil
|
|
| Definition |
A prostaglandins E that has formula C20H34O5.
|
|
| has effect |
http://purl.obolibrary.org/obo/OAE_0000388 http://purl.obolibrary.org/obo/OAE_0000497 http://purl.obolibrary.org/obo/OAE_0001373 http://purl.obolibrary.org/obo/OAE_0000081 http://purl.obolibrary.org/obo/OAE_0000589 http://purl.obolibrary.org/obo/OAE_0000557 http://purl.obolibrary.org/obo/OAE_0000377 http://purl.obolibrary.org/obo/OAE_0001437 http://purl.obolibrary.org/obo/OAE_0000882 http://purl.obolibrary.org/obo/OAE_0000630 http://purl.obolibrary.org/obo/OAE_0000218 http://purl.obolibrary.org/obo/OAE_0000335 http://purl.obolibrary.org/obo/OAE_0000650 http://purl.obolibrary.org/obo/OAE_0001046 http://purl.obolibrary.org/obo/OAE_0001186 http://purl.obolibrary.org/obo/OAE_0000801 http://purl.obolibrary.org/obo/OAE_0000567 http://purl.obolibrary.org/obo/OAE_0000373 http://purl.obolibrary.org/obo/OAE_0000319 http://purl.obolibrary.org/obo/OAE_0000021 http://purl.obolibrary.org/obo/OAE_0001448 http://purl.obolibrary.org/obo/OAE_0000317 http://purl.obolibrary.org/obo/OAE_0001436 http://purl.obolibrary.org/obo/OAE_0000382 http://purl.obolibrary.org/obo/OAE_0000600 http://purl.obolibrary.org/obo/OAE_0001538 http://purl.obolibrary.org/obo/OAE_0000403 http://purl.obolibrary.org/obo/OAE_0000551 http://purl.obolibrary.org/obo/OAE_0000283 http://purl.obolibrary.org/obo/OAE_0001057 http://purl.obolibrary.org/obo/OAE_0000400 http://purl.obolibrary.org/obo/OAE_0000645 http://purl.obolibrary.org/obo/OAE_0000414 http://purl.obolibrary.org/obo/OAE_0000355 http://purl.obolibrary.org/obo/OAE_0000780 http://purl.obolibrary.org/obo/OAE_0000505 http://purl.obolibrary.org/obo/OAE_0001443 http://purl.obolibrary.org/obo/OAE_0000779 http://purl.obolibrary.org/obo/OAE_0000347 http://purl.obolibrary.org/obo/OAE_0000362 http://purl.obolibrary.org/obo/OAE_0000374 http://purl.obolibrary.org/obo/OAE_0000358 http://purl.obolibrary.org/obo/OAE_0001309 |
|
| has pharmacological target | ||
| has role |
http://purl.obolibrary.org/obo/CHEBI_50249 |
|
| InChI |
InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h12-13,15-17,19,21,23H,2-11,14H2,1H3,(H,24,25)/b13-12+/t15-,16+,17+,19+/m0/s1
|
|
| InChIKey |
InChIKey=GMVPRGQOIOIIMI-DWKJAMRDSA-N
|
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_1992 |
|
| is substrate of | ||
| is transported by | ||
| label |
prostaglandin E1
|
|
| modulates | ||
| prefixIRI |
obo2:CHEBI_15544
|
|
| prefLabel |
prostaglandin E1
|
|
| SMILES |
CCCCC[C@H](O)\\C=C\\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O CCCCC[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(O)=O
|
|
| Synonym |
C20H34O5 (13E)-(15S)-11alpha,15-Dihydroxy-9-oxoprost-13-enoate Caverject Prostin VR (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid PGE-1 Edex Muse Befar alprostadil 11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid (13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid PGE1 Alprostadil alprostadilum Prostaglandin E1 7-[(1R,2R,3R)-3-hydroxy-2-[(3S)-3-hydroxyoct-1-en-1-yl]-5-oxocyclopentyl]heptanoic acid
|
|
| xref |
Wikipedia:http://en.wikipedia.org/wiki/Alprostadil National Drug Code Directory:0703-1501-02 ChEMBL:108130 CASRN:745-65-3 Guide To Pharmacology:1882 KEGG DRUG:D00180 LIPID MAPS:LMFA03010134 Beilstein:2061617 PubChem Substance:46508029 DrugBank:DB00770 ChEBI:15544 PubChem Compound:5280723 IUPHAR:1882 PharmGKB:PA448334 Drugs.com:http://www.drugs.com/cdi/alprostadil.html RxList:http://www.rxlist.com/cgi/generic/alprostadil.htm ChemSpider:131636 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/cav1073.shtml Drugs Product Database (DPD):2241680 KEGG COMPOUND:C04741
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| subClassOf |
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