loading...| Preferred Name | cefalotin | |
| Synonyms |
CET CEPHALOTHIN 7-(2-Thienylacetamido)cephalosporanic acid 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid (6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefalotine 7-(2'-thienylacetamido)cephalosporanic acid Cefalothin Cephalotin cefalotinum cefalotina C16H16N2O6S2 cefalotin 7-(Thiophene-2-acetamido)cephalosporin Cephalothin 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_124991 |
|
| AHFScode |
08:12.06.04 |
|
| altId |
CHEBI:50895 CHEBI:41547 |
|
| ATCCode |
J01DB03 |
|
| binds |
http://purl.obolibrary.org/obo/dinto_0217 http://purl.obolibrary.org/obo/dinto_0413 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2437 http://purl.obolibrary.org/obo/dinto_3285 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_1920 http://purl.obolibrary.org/obo/dinto_0758 http://purl.obolibrary.org/obo/dinto_4015 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_4301 http://purl.obolibrary.org/obo/dinto_2789 |
|
| CASRN |
153-61-7 |
|
| DBBrand |
coaxin averon-1 cemastin keflin seffin |
|
| DBname |
cefalotin |
|
| DBSynonym |
cephalothin sodium cephalotin cls cefalotinum [inn-latin] cefalotine [inn-french] cefalotina [inn-spanish] cephalothin cefalothin cephalothinum |
|
| Definition |
A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections. |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0413 http://purl.obolibrary.org/obo/dinto_2437 http://purl.obolibrary.org/obo/dinto_3285 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_1920 http://purl.obolibrary.org/obo/dinto_0758 |
|
| has role | ||
| InChI |
InChI=1S/C16H16N2O6S2/c1-8(19)24-6-9-7-26-15-12(14(21)18(15)13(9)16(22)23)17-11(20)5-10-3-2-4-25-10/h2-4,12,15H,5-7H2,1H3,(H,17,20)(H,22,23)/t12-,15-/m1/s1 |
|
| InChIKey |
InChIKey=XIURVHNZVLADCM-IUODEOHRSA-N |
|
| inhibits |
http://purl.obolibrary.org/obo/dinto_0413 http://purl.obolibrary.org/obo/dinto_1977 http://purl.obolibrary.org/obo/dinto_1975 http://purl.obolibrary.org/obo/dinto_2437 http://purl.obolibrary.org/obo/dinto_3285 http://purl.obolibrary.org/obo/dinto_3289 http://purl.obolibrary.org/obo/dinto_1920 http://purl.obolibrary.org/obo/dinto_0758 http://purl.obolibrary.org/obo/dinto_4015 http://purl.obolibrary.org/obo/dinto_4065 http://purl.obolibrary.org/obo/dinto_2004 http://purl.obolibrary.org/obo/dinto_4301 |
|
| label |
cefalotin |
|
| may interact with | ||
| prefixIRI |
obo2:CHEBI_124991 |
|
| prefLabel |
cefalotin |
|
| related with | ||
| SMILES |
[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)CC1=CC=CS1)C(O)=O [H][C@@]1(NC(=O)Cc2cccs2)C(=O)N2C(C(O)=O)=C(COC(C)=O)CS[C@]12[H] |
|
| Synonym |
CET CEPHALOTHIN 7-(2-Thienylacetamido)cephalosporanic acid 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid (6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-[2-(thiophen-2-yl)acetamido]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid cefalotine 7-(2'-thienylacetamido)cephalosporanic acid Cefalothin Cephalotin cefalotinum cefalotina C16H16N2O6S2 cefalotin 7-(Thiophene-2-acetamido)cephalosporin Cephalothin 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid |
|
| xref |
KEGG COMPOUND:C07761 CiteXplore:23680238 DrugBank:DB00456 CiteXplore:23472927 ChEBI:124991 CiteXplore:12833570 PDBeChem:CLS PubChem Compound:6024 PharmGKB:PA448886 CiteXplore:13963283 KEGG DRUG:D07635 CASRN:153-61-7 ChemSpider:5802 Wikipedia:Cephalothin Wikipedia:http://en.wikipedia.org/wiki/Cefalotin Drugs Product Database (DPD):2060051 CiteXplore:1701026 CiteXplore:6176550 CiteXplore:10930630 CiteXplore:1384868 CiteXplore:12569987 Patent:FR1384197 PubChem Substance:46509079 CiteXplore:2083978 PDB:CEO Beilstein:945586 Patent:US3218318 |
|
| subClassOf |