loading...| Preferred Name |
diclofenamide |
|
| Synonyms |
diclofenamidum dichlorophenamide Dichlorophenamide DICHLORPHENAMIDE 1,3-disulfamoyl-4,5-dichlorobenzene dichlorphenamide 4,5-dichloro-m-benzenedisulfonamide 1,3-disulfamyl-4,5-dichlorobenzene 4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE Diclofenamide diclofenamida Dichlorphenamide dichlofenamide C6H6Cl2N2O4S2 4,5-dichloro-1,3-benzenedisulfonamide DICLOFENAMIDE 3,4-dichloro-5-sulfamylbenzenesulfonamide 4,5-dichloro-benzene-1,3-disulfonic acid diamide 4,5-dichloro-1,3-disulfamoylbenzene 4,5-dichlorobenzene-1,3-disulfonamide |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_101085 |
|
| altId |
CHEBI:4505 CHEBI:47477 |
|
| ATCCode |
S01EC02 |
|
| CASRN |
120-97-8 |
|
| DBBrand |
dasanide glaucol daranide oratrol antidrasi |
|
| DBname |
dichlorphenamide |
|
| DBSynonym |
dichlorophenamide diclofenamide dichlorphenamid dichlofenamide 4,5-dicholorobenzene-1,3-disulfonamide diclofenamida [inn-spanish] diclofenamidum [inn-latin] |
|
| Definition |
Benzene-1,3-disulfonamide in which the hydrogens at positions 4 and 5 are substituted by chlorine. An oral carbonic anhydrase inhibitor, it partially suppresses the secretion (inflow) of aqueous humor in the eye and so reduces intraocular pressure. It is used for the treatment of glaucoma. |
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| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_0512 http://purl.obolibrary.org/obo/dinto_1927 |
|
| has role |
http://purl.obolibrary.org/obo/CHEBI_39456 |
|
| InChI |
InChI=1S/C6H6Cl2N2O4S2/c7-4-1-3(15(9,11)12)2-5(6(4)8)16(10,13)14/h1-2H,(H2,9,11,12)(H2,10,13,14) |
|
| InChIKey |
InChIKey=GJQPMPFPNINLKP-UHFFFAOYSA-N |
|
| induces | ||
| inhibits |
http://purl.obolibrary.org/obo/dinto_0512 http://purl.obolibrary.org/obo/dinto_1927 |
|
| label |
diclofenamide |
|
| may interact with |
http://purl.obolibrary.org/obo/CHEBI_15365 http://purl.obolibrary.org/obo/CHEBI_3176 |
|
| prefixIRI |
obo2:CHEBI_101085 |
|
| prefLabel |
diclofenamide |
|
| SMILES |
NS(=O)(=O)C1=CC(=C(Cl)C(Cl)=C1)S(N)(=O)=O NS(=O)(=O)c1cc(Cl)c(Cl)c(c1)S(N)(=O)=O |
|
| Synonym |
diclofenamidum dichlorophenamide Dichlorophenamide DICHLORPHENAMIDE 1,3-disulfamoyl-4,5-dichlorobenzene dichlorphenamide 4,5-dichloro-m-benzenedisulfonamide 1,3-disulfamyl-4,5-dichlorobenzene 4,5-DICHLOROBENZENE-1,3-DISULFONAMIDE Diclofenamide diclofenamida Dichlorphenamide dichlofenamide C6H6Cl2N2O4S2 4,5-dichloro-1,3-benzenedisulfonamide DICLOFENAMIDE 3,4-dichloro-5-sulfamylbenzenesulfonamide 4,5-dichloro-benzene-1,3-disulfonic acid diamide 4,5-dichloro-1,3-disulfamoylbenzene 4,5-dichlorobenzene-1,3-disulfonamide |
|
| xref |
ChEBI:101085 CASRN:120-97-8 RxList:http://www.rxlist.com/cgi/generic/dichlorphen.htm KEGG DRUG:D00518 DrugBank:DB01144 NIST Chemistry WebBook:120-97-8 Patent:US2835702 PDBeChem:I7A PubChem Substance:46505039 BindingDB:10883 Beilstein:2703329 Drugs.com:http://www.drugs.com/mtm/dichlorphenamide.html ChemSpider:2930 PubChem Compound:3038 PDB:I7A KEGG COMPOUND:C07459 Wikipedia:Dichlorphenamide PharmGKB:PA164745512 |
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| subClassOf |