loading...| Preferred Name |
yohimbine |
|
| Synonyms |
methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate Johimbin (+)-yohimbine quebrachine 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester aphrodine Yohimbine methyl 17alpha-hydroxyyohimban-16alpha-carboxylate yohimbic acid methyl ester Yohimbin (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester Quebrachin corynine C21H26N2O3 |
|
| ID |
http://purl.obolibrary.org/obo/CHEBI_10093 |
|
| AHFScode |
92:00.00 |
|
| ATCCode |
G04BE04 |
|
| blocks |
http://purl.obolibrary.org/obo/dinto_2804 http://purl.obolibrary.org/obo/dinto_0510 http://purl.obolibrary.org/obo/dinto_4010 http://purl.obolibrary.org/obo/dinto_3877 http://purl.obolibrary.org/obo/dinto_2858 http://purl.obolibrary.org/obo/dinto_1581 http://purl.obolibrary.org/obo/dinto_0392 |
|
| CASRN |
146-48-5 |
|
| DBBrand |
yocon baron-x dayto himbin yovital actibine yoman thybine aphrodyne yohimex yohimar |
|
| DBname |
yohimbine |
|
| DBSynonym |
yohimbin |
|
| Definition |
An indole alkaloid with alpha2-adrenoceptor antagonist activity. It is produced by Corynanthe johimbe and Rauwolfia serpentina. |
|
| has pharmacological target |
http://purl.obolibrary.org/obo/dinto_3877 |
|
| has role | ||
| InChI |
InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19+/m0/s1 |
|
| InChIKey |
InChIKey=BLGXFZZNTVWLAY-SCYLSFHTSA-N |
|
| inhibits | ||
| is metabolised by | ||
| label |
yohimbine |
|
| may interact with | ||
| prefixIRI |
obo2:CHEBI_10093 |
|
| prefLabel |
yohimbine |
|
| related with | ||
| SMILES |
[H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCC3=C1NC1=CC=CC=C31)C2 [H][C@@]12CC[C@H](O)[C@H](C(=O)OC)[C@@]1([H])C[C@]1([H])N(CCc3c1[nH]c1ccccc31)C2 |
|
| Synonym |
methyl (1S,15R,18S,19R,20S)-18-hydroxy-3,13-diazapentacyclo[11.8.0.0^{2,10}.0^{4,9}.0^{15,20}]henicosa-2(10),4,6,8-tetraene-19-carboxylate Johimbin (+)-yohimbine quebrachine 17alpha-hydroxyyohimban-16alpha-carboxylic acid methyl ester aphrodine Yohimbine methyl 17alpha-hydroxyyohimban-16alpha-carboxylate yohimbic acid methyl ester Yohimbin (16alpha,17alpha)-17-hydroxyyohimban-16-carboxylic acid methyl ester Quebrachin corynine C21H26N2O3 |
|
| xref |
Beilstein:4720812 PubChem Compound:8969 ChEMBL:115191 Drugs.com:http://www.drugs.com/cdi/yohimbine.html Drugs Product Database (DPD):795283 CASRN:146-48-5 ChemSpider:8622 Wikipedia:http://en.wikipedia.org/wiki/Yohimbine PharmGKB:PA451946 PubChem Substance:46504602 Beilstein:97276 KEGG DRUG:D08685 KEGG COMPOUND:C09256 PDRhealth:http://www.pdrhealth.com/drug_info/rxdrugprofiles/drugs/yoc1492.shtml NIST Chemistry WebBook:146-48-5 ChEBI:10093 RxList:http://www.rxlist.com/cgi/generic/yohimbine.htm DrugBank:DB01392 |
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| subClassOf |