Drug Interaction and Evidence Ontology

Last uploaded: November 17, 2017
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Preferred Name

Hep G2 cell
Synonyms
Definitions

an immortal human liver-derived cell line cell that is part of the Hep G2 cell line HepG2 was derived from a liver hepatocellular carcinoma of a 15 year-old Caucasian male. HepG2 cells secrete a variety of major plasma proteins. They are a suitable in vitro model system for the study of polarized human hepatocytes, with high degree of morphological and functional differentiation in vitro. It can be used for hepatic metabolism, transport, and toxicity evaluations in vitro. It was tested negative for HBV.
ID

http://purl.obolibrary.org/obo/DIDEO_00000185
comment

HepG2 was derived from a liver hepatocellular carcinoma of a 15 year-old Caucasian male. HepG2 cells secrete a variety of major plasma proteins. They are a suitable in vitro model system for the study of polarized human hepatocytes, with high degree of morphological and functional differentiation in vitro. It can be used for hepatic metabolism, transport, and toxicity evaluations in vitro. It was tested negative for HBV.
creator

John Judkins
label

Hep G2 cell
prefixIRI

DIDEO:00000185
prefLabel

Hep G2 cell
term editor

John Judkins
textual definition

an immortal human liver-derived cell line cell that is part of the Hep G2 cell line
subClassOf

http://purl.obolibrary.org/obo/CLO_0000001
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